新加坡亚洲人的基底细胞癌特征及完全与不完全切除肿瘤的比较

背景：大多数已报道的基底细胞癌（BCCs）的特征主要是依据高加索患者。而关于亚洲人中不完全切除BCCs的特征少见报道。目的：本研究调查了新加坡亚洲居民的BCCs特征，并对常规外科切除术后完全切除与不完全切除肿瘤进行了比较。患者和方法：收集1991--1995年间在国家皮肤病中心行肿瘤切除术的原发性BCC患者的病历进行回顾性研究。结果：166例BCC患者（男女比0．95；平均年龄70．9岁）的185个组织病检确诊的BCCs记录在案。发病最高比例（27．1％）在8l～90岁年龄组。与普查资料相比，华人BCCs患者的比例明显增高（P〈0．001）。肿瘤平均直径为12．0mm，且大多数（84．3％）位于头颈部。28处（15．1％）皮损被不完全切除，多位于鼻部及鼻唇沟。不完全切除的基底细胞癌较完全切除的基底细胞癌更多发生于面中部及躯干部（P=0．003），但与肿瘤大小、肿瘤持续时间、患者年龄、种族及性别无显著相关。平均随访74个月，     

科学模型与中医各家养生学说

从西方科学哲学模型论的角度来说,各养生学派是在一定的生活情况、环境和时间上运用来指导养生,因而各家养生学说就是的一个科学模型.模型不是真理,而是适应经验上遇到的某些生活情况而创造的.运用科学模型的角度看中医理论四位养生大家的养生思想.     

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目的 通过对术后复发的直肠癌手术切除与保守治疗的疗效比较，探讨合理的治疗方法。方法 对1997年1月1日至2001年12月31日新加坡中央医院结肠直肠外科学部643例行直肠癌根治术病人的相关资料进行统计分析。结果 643例行直肠癌根治术后有81例复发，其中31例(4．8％)为局部复发，50例(7．8％)为远处转移。42例再度接受手术治疗，其中25例(59．5％)行局部复发切除术。然而，与39例转移癌辅助治疗相比，再次手术的病例并没有显著地提高生存率。结论 与非手术治疗相比，根治术后直肠癌局部复发再次手术切除，未必能显著地提高病人的生存率。     

增生性糖尿病性视网膜病变的手术治疗--玻璃体切除联合晶状体超声乳化吸出术

目的　评价玻璃体手术联合晶状体乳化吸出术治疗增生性糖尿病性视网膜病变的临床效果。方法　回顾性分析3 8例 (4 1眼 )行玻璃体切除联合晶状体乳化吸出术的伴有白内障的增生性糖尿病性视网膜病变的临床资料 ,其中 3 7眼同期植入后房型人工晶状体。结果　术后随访 3～ 5 5月 ,平均 (12± 10 6)月。 2 7眼 (65 9% )术后视力改善。术中无并发症发生。术后并发症有 :前房炎性反应 3眼 (7 3 % ) ,玻璃体积血 5眼 (12 2 % ) ,复发性视网膜脱离 3眼 (7 3 % ) ,新生血管性青光眼 4眼(9 8% )。 14眼术后需要进一步治疗 ,包括眼内光凝、玻璃体手术和青光眼滤过手术。结论　玻璃体切除联合晶状体乳化吸出术治疗增生性糖尿病性视网膜病变 ,可使大多数患者的视力改善 ,手术是安全的     

Seroepidemiologic Effects of Influenza A(H1N1)pdm09 in Australia,New Zealand,and Singapore

To estimate population attack rates of influenza A(H1N1)pdm2009 in the Southern Hemisphere during June–August 2009, we conducted several serologic studies. We pooled individual-level data from studies using hemagglutination inhibition assays performed in Australia, New Zealand, and Singapore. We determined seropositive proportions (titer >40) for each study region by age-group and sex in pre- and postpandemic phases, as defined by jurisdictional notification data. After exclusions, the pooled database consisted of, 4,414 prepandemic assays and 7,715 postpandemic assays. In the prepandemic phase, older age groups showed greater seropositive proportions, with age-standardized, community-based proportions ranging from 3.5% in Singapore to 11.9% in New Zealand. In the postpandemic phase, seropositive proportions ranged from 17.5% in Singapore to 30.8% in New Zealand, with highest proportions seen in school-aged children. Pregnancy and residential care were associated with lower postpandemic seropositivity, whereas Aboriginal and Torres Strait Islander Australians and Pacific Peoples of New Zealand had greater postpandemic seropositivity.     

Newborn and paediatric resuscitation 2011 guidelines

We present the revised guidelines for newborn and paediatric resuscitation for Singapore. The 2010 International Liaison Committee on Resuscitation consensus on science as well as the main recommendations from the European Resuscitation Council and American Heart Association were debated and discussed. The final recommendations for the Singapore National Resuscitation Council were derived after carefully reviewing the current available evidence in the literature and balancing the local clinical climate of practice. In addition, much effort was spent on aligning the paediatric and neonatal recommendations with the adult (especially Basic Cardiac Life Support) recommendations.