全文获取类型
收费全文 | 2784篇 |
免费 | 235篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 179篇 |
妇产科学 | 61篇 |
基础医学 | 403篇 |
口腔科学 | 15篇 |
临床医学 | 208篇 |
内科学 | 536篇 |
皮肤病学 | 48篇 |
神经病学 | 217篇 |
特种医学 | 57篇 |
外国民族医学 | 1篇 |
外科学 | 437篇 |
综合类 | 155篇 |
预防医学 | 191篇 |
眼科学 | 34篇 |
药学 | 217篇 |
中国医学 | 14篇 |
肿瘤学 | 246篇 |
出版年
2023年 | 16篇 |
2021年 | 53篇 |
2020年 | 34篇 |
2019年 | 58篇 |
2018年 | 67篇 |
2017年 | 47篇 |
2016年 | 73篇 |
2015年 | 71篇 |
2014年 | 84篇 |
2013年 | 116篇 |
2012年 | 155篇 |
2011年 | 171篇 |
2010年 | 86篇 |
2009年 | 104篇 |
2008年 | 136篇 |
2007年 | 149篇 |
2006年 | 152篇 |
2005年 | 124篇 |
2004年 | 127篇 |
2003年 | 106篇 |
2002年 | 93篇 |
2001年 | 69篇 |
2000年 | 80篇 |
1999年 | 74篇 |
1998年 | 29篇 |
1997年 | 19篇 |
1996年 | 15篇 |
1992年 | 35篇 |
1991年 | 49篇 |
1990年 | 49篇 |
1989年 | 29篇 |
1988年 | 32篇 |
1987年 | 30篇 |
1986年 | 33篇 |
1985年 | 31篇 |
1984年 | 19篇 |
1981年 | 20篇 |
1980年 | 16篇 |
1979年 | 31篇 |
1978年 | 24篇 |
1977年 | 23篇 |
1976年 | 20篇 |
1975年 | 23篇 |
1974年 | 22篇 |
1973年 | 28篇 |
1972年 | 23篇 |
1971年 | 26篇 |
1970年 | 17篇 |
1969年 | 19篇 |
1968年 | 13篇 |
排序方式: 共有3044条查询结果,搜索用时 500 毫秒
1.
Metabolic abnormalities of gastrointestinal mucosa in celiac disease: An in vitro proton nuclear magnetic resonance spectroscopy study 下载免费PDF全文
2.
3.
I. Fishtik C.A. Callaghan J.D. Fehribach R. Datta 《Journal of electroanalytical chemistry (Lausanne, Switzerland)》2005,576(1):57-63
The reaction route (RR) graph approach recently developed by us for complex, non-linear kinetic mechanisms is applied to the hydrogen oxidation and evolution reactions. A corresponding RR graph is constructed and translated into an equivalent electrical circuit network by associating each elementary step with a characteristic resistance for the steady-state case and considering the overall reaction as a power source. It is further shown that the steady-state kinetics of the reaction can be investigated employing the conventional methods of the electrical network theory. Using a set of rate constants for the hydrogen evolution reaction (her) in alkaline solutions from the literature, the dominant RRs are identified and simplified mechanisms and kinetics derived. 相似文献
4.
ImmunoCyt/uCyt is a fluorescent test combining three monoclonal antibodies. In this study, it has been tested as a complement to cytology in the detection of urothelial carcinoma in urine. It has been performed simultaneously with standard cytology and cystoscopy on 870 urine analyses from one hospital. In 136 cases, one or more bladder tumors were found. Overall sensitivity of cytology, ImmunoCyt/uCyt and combined analyses reached 29, 74 and 84%, respectively, and overall specificity was 98, 62 and 61%. The negative predictive value of cytology, ImmunoCyt/uCyt and both analyses was 88, 93 and 95%, respectively, and the positive predictive value was 70, 26 and 29%. The sensitivity of cytology for low malignant potential neoplasms, low- and high-grade papillary carcinomas was 6, 18 and 53%, while it reached 71, 79 and 93% when combined with ImmunoCyt/uCyt. The sensitivity of cytology for stages Ta, T1, T2 and over and Tis tumors was 12, 67, 47 and 50%, while it reached 78, 83, 79 and 100% when combined with ImmunoCyt/uCyt. In the absence of tumor on cystoscopy but with positive ImmunoCyt/uCyt, 18% of patients developed a tumor, 2-6 months later. Of the 109 cases diagnosed as suspicious for malignancy by cytology, a tumor was present in 30 cases and ImmunoCyt/uCyt was positive in 22 (73%) of them. In conclusion, ImmunoCyt/uCyt may be used to postpone cystoscopies in patients followed for bladder cancer and may help to save cytologist and pathologist screening time. 相似文献
5.
6.
A Terenzi I Lubin T Lapidot O Salomon Y Faktorowich I Rabi M F Martelli Y Reisner 《Transplantation》1990,50(4):717-720
7.
8.
9.
A. Datta R. David S. Glennie D. Scott E. Cernuda-Morollon R. I. Lechler A. J. Ridley F. M. Marelli-Berg 《American journal of transplantation》2006,6(12):2871-2883
The best-characterized mechanism of the action of immunosuppressive drugs is to prevent T-cell clonal expansion, thus containing the magnitude of the ensuing immune response. As T-cell recruitment to the inflammatory site is another key step in the development of T-cell-mediated inflammation, we analyzed and compared the effects of two commonly used immunosuppressants, cyclosporin A (CsA) and the rapamycin-related compound SDZ-RAD, on the motility of human CD4+ T cells. We show that CsA, but not SDZ-RAD, inhibits T-cell transendothelial migration in vitro. CsA selectively impaired chemokine-induced T-cell chemotaxis while integrin-mediated migration was unaffected. The inhibition of T-cell chemotaxis correlated with reduced AKT/PKB but not ERK activation following exposure to the chemokine CXCL-12/SDF-1. In addition, CsA, but not SDZ-RAD, prevents some T-cell receptor-mediated effects on T-cell motility. Finally, we show that CsA, but not SDZ-RAD inhibits tissue infiltration by T cells in vivo. Our data suggest a prominent antiinflammatory role for CsA in T-cell-mediated tissue damage, by inhibiting T-cell trafficking into tissues in addition to containing clonal expansion. 相似文献
10.