全文获取类型
收费全文 | 23763篇 |
免费 | 1110篇 |
国内免费 | 117篇 |
专业分类
耳鼻咽喉 | 606篇 |
儿科学 | 1469篇 |
妇产科学 | 820篇 |
基础医学 | 1887篇 |
口腔科学 | 1098篇 |
临床医学 | 1951篇 |
内科学 | 4519篇 |
皮肤病学 | 740篇 |
神经病学 | 1570篇 |
特种医学 | 957篇 |
外科学 | 5194篇 |
综合类 | 340篇 |
一般理论 | 10篇 |
预防医学 | 902篇 |
眼科学 | 670篇 |
药学 | 1309篇 |
中国医学 | 127篇 |
肿瘤学 | 821篇 |
出版年
2024年 | 17篇 |
2023年 | 242篇 |
2022年 | 165篇 |
2021年 | 574篇 |
2020年 | 365篇 |
2019年 | 477篇 |
2018年 | 692篇 |
2017年 | 543篇 |
2016年 | 708篇 |
2015年 | 721篇 |
2014年 | 927篇 |
2013年 | 1217篇 |
2012年 | 1544篇 |
2011年 | 1784篇 |
2010年 | 945篇 |
2009年 | 681篇 |
2008年 | 1461篇 |
2007年 | 1700篇 |
2006年 | 1664篇 |
2005年 | 1703篇 |
2004年 | 1502篇 |
2003年 | 1303篇 |
2002年 | 1231篇 |
2001年 | 499篇 |
2000年 | 571篇 |
1999年 | 358篇 |
1998年 | 163篇 |
1997年 | 108篇 |
1996年 | 109篇 |
1995年 | 71篇 |
1994年 | 48篇 |
1993年 | 41篇 |
1992年 | 67篇 |
1991年 | 88篇 |
1990年 | 76篇 |
1989年 | 68篇 |
1988年 | 57篇 |
1987年 | 57篇 |
1986年 | 49篇 |
1985年 | 46篇 |
1984年 | 23篇 |
1983年 | 27篇 |
1979年 | 26篇 |
1978年 | 25篇 |
1976年 | 17篇 |
1974年 | 22篇 |
1973年 | 29篇 |
1972年 | 23篇 |
1971年 | 18篇 |
1966年 | 16篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Candayan Ayşe Yunisova Gulshan Çakar Arman Durmuş Hacer Başak A. Nazlı Parman Yeşim Battaloğlu Esra 《Neurogenetics》2020,21(1):73-78
neurogenetics - Charcot-Marie-Tooth (CMT) disease is the most common inherited neuropathy with a prevalence of 1 in 2500 individuals worldwide. Here, we report three Turkish siblings from... 相似文献
2.
Karaosmanoglu Ali Devrim Onur Mehmet Ruhi Salman Mehmet Coskun Usubutun Alp Karcaaltincaba Musturay Ozmen Mustafa Nasuh Akata Deniz 《Abdominal imaging》2019,44(4):1493-1505
Abdominal Radiology - Metastatic involvement of the ovaries is not rare. The most common tumor types metastasizing to the ovaries, from non-gynecological organs, are breast, colorectal, gastric,... 相似文献
3.
4.
5.
6.
7.
8.
Quang Ngoc Nguyen Linh Dieu Vuong Van-Long Truong To Van Ta Nam Trung Nguyen Hung Phi Nguyen Ha Hoang Chu 《Pathology, research and practice》2019,215(5):885-892
Genetic and epigenetic alterations importantly contribute to the pathogenesis of lung cancer. In the study, we measured the frequency and distribution of molecular abnormalities of EGFR as well as the aberrant promoter methylations of BRCA1, MGMT, MLH1, and RASSF1A in Vietnamese lung adenocarcinomas. We investigated the association between genetic and epigenetic alteration, and between each abnormality with clinicopathologic parameters. Somatic EGFR mutation that was found in 49/139 (35.3%) lung adenocarcinomas showed a significant association with young age, female gender, and non-smokers. EGFR overexpression was identified in 82 tumors (59.0%) and statistical relationships with EGFR or BRCA1 methylation but not EGFR mutation. In addition, EGFR, BRCA1, MGMT, MLH1, and RASSF1A methylations were found in 33 (23.7%), 41 (29.5%), 46 (33.1%), 28 (20.1%), and 41 (29.5%) cases of a total of 139 lung adenocarcinomas, respectively. The RASSF1A methylation was found to be linked to the smoking habit. Methylations in MGMT and RASSF1A were also found to correlate with metastasis status. Furthermore, the distribution of EGFR mutation and that of BRCA1, MGMT or RASSF1A methylation were significantly exclusive in lung adenocarcinomas. The main finding of our study demonstrate that epigenetic abnormalities might play a critical role for the lung tumorigenesis in patients with smoking history and metastasis, and partly affect the predictive value of EGFR mutations through blocking expression due to promoter EGFR hypermethylation. Mutually exclusive distribution of genetic and epigenetic alterations reflects differently biological characteristics in the etiology of lung adenocarcinomas. 相似文献
9.
Increased arterial stiffness in young normotensive patients with Turner syndrome: associations with vascular biomarkers 下载免费PDF全文
10.
Rebecca Wright Caleb Ferguson Mustafa Bodrick Hanan Balkhy Debra Jackson Patricia M. Davidson 《Journal of clinical nursing》2020,29(13-14):2723-2729