全文获取类型
收费全文 | 7937篇 |
免费 | 388篇 |
国内免费 | 71篇 |
专业分类
耳鼻咽喉 | 39篇 |
儿科学 | 296篇 |
妇产科学 | 46篇 |
基础医学 | 1037篇 |
口腔科学 | 121篇 |
临床医学 | 454篇 |
内科学 | 2338篇 |
皮肤病学 | 329篇 |
神经病学 | 507篇 |
特种医学 | 331篇 |
外科学 | 1374篇 |
综合类 | 28篇 |
一般理论 | 1篇 |
预防医学 | 215篇 |
眼科学 | 155篇 |
药学 | 438篇 |
中国医学 | 14篇 |
肿瘤学 | 673篇 |
出版年
2023年 | 43篇 |
2022年 | 39篇 |
2021年 | 152篇 |
2020年 | 93篇 |
2019年 | 118篇 |
2018年 | 150篇 |
2017年 | 117篇 |
2016年 | 132篇 |
2015年 | 159篇 |
2014年 | 216篇 |
2013年 | 267篇 |
2012年 | 435篇 |
2011年 | 465篇 |
2010年 | 287篇 |
2009年 | 236篇 |
2008年 | 451篇 |
2007年 | 476篇 |
2006年 | 395篇 |
2005年 | 496篇 |
2004年 | 520篇 |
2003年 | 524篇 |
2002年 | 539篇 |
2001年 | 97篇 |
2000年 | 99篇 |
1999年 | 122篇 |
1998年 | 132篇 |
1997年 | 100篇 |
1996年 | 113篇 |
1995年 | 88篇 |
1994年 | 87篇 |
1993年 | 71篇 |
1992年 | 117篇 |
1991年 | 78篇 |
1990年 | 99篇 |
1989年 | 79篇 |
1988年 | 87篇 |
1987年 | 68篇 |
1986年 | 63篇 |
1985年 | 72篇 |
1984年 | 59篇 |
1983年 | 53篇 |
1982年 | 36篇 |
1981年 | 45篇 |
1980年 | 44篇 |
1979年 | 34篇 |
1978年 | 39篇 |
1977年 | 24篇 |
1974年 | 18篇 |
1973年 | 17篇 |
1969年 | 20篇 |
排序方式: 共有8396条查询结果,搜索用时 31 毫秒
1.
2.
3.
Akihiko Bo Shinichi Imura Hironori Omori Yasuhiro Okumura Masao Ando Hisatoshi Baba Patrick White Al Zarnowski 《Journal of orthopaedic science》1997,2(5):301-312
The fit and fill of the femoral canal are critical to the success of cementless femoral stems in total hip arthroplasty. It
is difficult for conventional stems to provide a good fit and fill for the femora of patients with secondary osteoarthritis.
Based on measurements of 100 femora of these patients, we designed two types of Fukui Medical School (FMS) stems with a proximal
lateral flare that differed in the medial radius. We compared the fit and fill of the FMS stems with those of four conventional
stems, using computer simulation. The mean proximal fit and total fit of the FMS stems were 46% and 53% respectively, a significant
improvement compared with the other stems examined. The mean fill of FMS stems was 82% at the lower end of the lesser trochanter
and 84% at the upper end of the isthmus, values that were significantly higher than those of the other stems. Since September
1995, we have implanted FMS stems in 15 hips with secondary osteoarthritis. Radiographic evaluations showed that the canal
fill of the FMS stems was significantly greater in the proximal femur compared with other stems previously inserted at our
department.
A summary of this paper was presented at the 9th Symposium on Computer-Assisted Radiology; June 1995, Berlin, and at the 8th
International Symposium on Technology in Arthroplasty; September 1995, Puerto Rico. 相似文献
4.
A Kubota A Okada K Imura H Kawahara R Nezu S Kamata Y Takagi 《Journal of pediatric surgery》1990,25(6):618-621
The effect of metronidazole (MNZ) on hepatic dysfunction associated with total parenteral nutrition (TPN) in neonates was investigated. Neonates receiving TPN for more than 2 weeks were divided into three groups. In group 1, TPN was given alone, in group 2, 25 mg/kg/d of MNZ was administered intravenously for the first 2 weeks of TPN, and in group 3, 50 mg/kg/d of MNZ was given for the first 3 weeks of TPN. Several parameters of liver function tests (LFTs) during the first 4 weeks of TPN were compared among these three groups. There was no significant difference of these parameters between group 1 and group 2. Although there was no significant difference of alkaline phosphatase, gamma-glutamyl transpeptidase, direct bilirubin, and total bile acid between groups 1 and 3, transaminase (glutamic oxaloacetic, glutamic pyruvic) of group 3 remained significantly lower than those of group 1. In conclusion, the administration of MNZ 50 mg/kg/d for 3 weeks, at least, prevented the elevation of transaminase during TPN in neonates, suggesting the possible involvement of intestinal anaerobic flora in the pathogenesis of TPN-associated liver dysfunction. 相似文献
5.
Haruhiko Nakamura Norihito Kawasaki Masahiko Taguchi Hajime Kitamura 《Annals of thoracic and cardiovascular surgery》2007,13(4):254-257
A minute small-cell lung cancer measuring 8 x 5 mm was detected and serially imaged by computed tomography for about a year preceding resection. Although this solid nodule showed a short overall doubling time (76 days), the growth curve included an early phase without apparent growth prior to the phase of rapid growth. Accordingly, lung cancer cannot be ruled out when a small nodule (<10 mm) does not enlarge in the first several months of computed tomographic follow-up. 相似文献
6.
7.
Yuji Maruyama Shigeo Yamauchi Hidetsugu Ogasawara Hajime Imura Masami Ochi Kazuo Shimizu 《Annals of thoracic and cardiovascular surgery》2006,12(1):60-62
Surgical treatment for subacute pulmonary arterial thromboembolism has previously been considered to be inappropriate. We undertook a pulmonary arterial thrombectomy and removal of a floating right heart thrombus in a patient who had been symptomatic for over a month. The pulmonary arterial pressure, which had been equal to the systemic pressure preoperatively, decreased gradually and almost normalized one month postoperatively. Pulmonary perfusion scintigraphy revealed a dramatic improvement and the patient returned to normal life activities. 相似文献
8.
Kuri Suzuki Daisuke Nishimi Hajime Morioka Masaharu Takanami 《International journal of urology》2007,14(4):370-372
The presence of blood in the ejaculate is called hematospermia or hemospermia. While often perceived as a symptom of little significance, hematospermia can cause great concern to men who experience it. We report an unusual case of hematospermia associated with pelvic arteriovenous malformation (AVM). A 60-year-old man who visited our hospital complaining of hematospermia and pollakisuria was found to have AVM and aneurysmal changes in the left side of the pelvis using computed tomography (CT). The patient was treated with steel coil embolization of the left inferior gluteal artery, and after the procedure the hematospermia and pollakisuria remained absent without flare-ups. 相似文献
9.
Aoyama Takao Yamamoto Koujirou Kotaki Hajime Sawada Yasufumi Iga Tatsuji 《Pharmaceutical research》1997,14(11):1601-1606
Purpose. The locomotive activity changes after intravenous (i.v.) administration of methylphenidate (MPD) in rats were pharmacodynamically analyzed.
Methods. MPD concentration in plasma, MPD concentration and dopamine (DA) level in striatal dialysate collected by microdialysis method, and the locomotor activity after i.v. administration of MPD (2, 5 and 10 mg/kg doses) were used for the analysis.
Results. The transport of MPD from plasma to the interstitial fluid in the brain could be expressed by the linear two-compartment model. The clockwise hysteresis between the MPD concentration and the DA level in the dialysate could be explained by the pharmacodynamic model considering Michaelis-Menten type reuptake process of the extracellular DA into the terminal of the dopaminergic nerve and its competitive inhibition by the extracellular MPD. The inhibition constant (Ki) of MPD for DA reuptake was estimated to be 41.3 ± 73.8 nM (mean ± SE), which was closely consistent with the in vitro value after correction with dialysis recovery. The relationship between DA level in dialysate and locomotor activity was expressed by the Emax model considering two contrary effects, hyperkinesia and stereotypy. The bi-phasic locomotor activity-time profiles after high dose of MPD could be represented by this model.
Conclusions. The developed model made it possible to explain the tolerance in DA increase and the complicated locomotive change induced by MPD, and may be useful for other DA reuptake inhibitors, such as amphetamine and methamphetamine. 相似文献
10.
Chronological changes in the complement system in sepsis 总被引:6,自引:0,他引:6
The time courses of serum complement levels and the severity of sepsis were compared in two groups of septic patients, one in which the patients survived (surviving group) and one in which they did not (nonsurviving group). The components of the complement system, namely, C3a, C4a, C5a, CH50, C3, C4, and C5, were measured at several points in time after the diagnosis of sepsis had been established. A 2-antibody radioimmunoassay was used to measure C3a, C4a, and C5a; the latex agglutination test was used to measure C3 and C4; nephelometry was used to measure C5; and Meyer's 50% hemolysis method was used to measure CH50. Following the diagnosis of sepsis, the levels of CH50, C3, and C4 were significantly lower in the nonsurviving than the surviving group, while the levels of C3a and C4a were significantly higher in the nonsurviving than the surviving group. The C5a levels were significantly higher in the nonsurviving than the surviving group, although no significant intergroup differences were subsequently noted. These results suggest that the serum levels of C3a, C4a, C5a, CH50, C3, and C4 could serve as indices of the severity of sepsis. Thus, monitoring the complement system may be useful for predicting the outcome of patients with sepsis. 相似文献