Infragenicular polytetrafluoroethylene bypass with distal vein cuffs for limb salvage: a contemporary series

HYPOTHESIS: Infragenicular polytetrafluoroethylene (PTFE)-venous cuff bypass grafting provides acceptable graft patency and limb salvage rates for limb salvage. DESIGN: Retrospective clinical review of a consecutive series. SETTING: Vascular surgical practice during the interval October 1, 2000, to September 1, 2004. PATIENTS: Fifty-one male and 49 female patients whose mean age was 76.9 years were operated on for tissue loss (67%), chronic rest pain (28%), and severe claudication (6%). Fifty-two percent of patients were diabetic and 49% had undergone previous leg bypass surgery. All patients had absent or inadequate greater saphenous vein, and 84 patients had absent or inadequate arm vein. INTERVENTIONS: One hundred five infragenicular PTFE bypasses were performed in these 100 patients. Distal targets were the infragenicular popliteal (40), posterior tibial (35), anterior tibial (16), and peroneal arteries (14). Sixty-eight venous cuffs were constructed from lesser saphenous vein. MAIN OUTCOME MEASURES: Graft patency, limb salvage, and patient survival were analyzed. RESULTS: Twelve early graft failures resulted in 7 leg amputations. The mean +/- SE 3-year primary patency and limb salvage rates were 64.4% +/- 12.8% and 74.4% +/- 11.9%, respectively. Perioperative mortality was 2.9% and 3-year survival was 38%. Graft follow-up ranged from 1 to 47 months with a mean of 13 months using life-table methods. CONCLUSIONS: For patients requiring arterial revascularization for limb salvage, in which autologous venous conduit is unavailable, distal venous cuff-PTFE bypass provides acceptable patency and limb salvage rates when viewed in the context of short life expectancy for these elderly patients.     

Arm veins for arterial revascularization of the leg: arteriographic and clinical observations

The results of 160 infrainguinal bypasses with arm vein grafts were analyzed. Seventy-three arteriograms were reviewed to identify early and late graft defects; arteriographic findings paralleled those described for saphenous vein grafts. Intimal fibrosis during the first postoperative year, observed in 16 grafts, was the most common defect. Aneurysmosis and elongation were rare, resulting in two graft replacements. Patency and limb salvage rates were calculated for 88 single-length femorodistal bypass grafts; the other 72 were inflow (eight) or outflow (22) jump grafts, sequential (eight) and composite autogenous vein grafts (34). The primary and secondary patency rates for single-length grafts were 74% and 80% at 1 year and 51% and 57% at 5 years, respectively. The limb salvage rate at 5 years was 82%. The survival rate for all patients was 44% at 5 years. These findings reconfirm our use of arm veins as bypass grafts when the saphenous vein is unavailable.     

Percutaneous transluminal angioplasty of the lower extremities by the vascular surgeon

As vascular surgeons, we performed 376 percutaneous transluminal angioplasties as follows: aorta and iliac arteries (148), infrainguinal arteries (191), and bypass grafts (21). Sixteen procedures were attempted but not completed. Neodymiumyttrium-aluminum-garnet laser thermoprobe was successfully used prior to balloon dilatations in 49 procedures. In contrast to our experience with operative intervention, percutaneous transluminal angioplasty was performed more frequently for claudication (75%), nondiabetics (72%), and women (45%). Median age was 71 years. Percutaneous transluminal angioplasty either preceded or followed proximal or distal open reconstruction in 58 extremities. Primary patency rates for iliac percutaneous transluminal angioplasties were: 94% at one month, 93% at six months, and 88% at one year. For infrainguinal percutaneous transluminal angioplasties they were 95%, 82%, and 70% at 1, 6, and 12 months, respectively. Repeat percutaneous transluminal angioplasty increased the one-year patency rates to 92% and 86% for iliac and infrainguinal percutaneous transluminal angioplasties, respectively. Preliminary data indicate that the six-month secondary patency rates were 82% for laser-assisted percutaneous transluminal angioplasty and 65% for percutaneous transluminal angioplasty of distal bypass grafts. The implementation of balloon angioplasty was facilitated by our 21 years of experience with arteriography. Percutaneous transluminal angioplasty has become a valuable adjunct to the practice of vascular surgery by expanding the therapeutic options for managing peripheral vascular occlusive disease.     

Large-vessel arterial occlusive disease in symptomatic upper extremity

Subclavian and axillary artery occlusive disease resulted in sufficient upper extremity symptoms to necessitate 30 vascular reconstructions in 28 patients over the past ten years. Female patients predominated, with a ratio of 2.5:1. The average age of the patients was 61 years. The incidence of diabetes mellitus was low (7%). Sixteen of 18 proximal subclavian lesions were on the left side, while more distal lesions were equally distributed on the left and right. Extrathoracic bypasses were used in all cases. Dacron grafts were used in 16 of 17 carotid-subclavian bypasses. Autogenous vein grafts were used in 11 of 13 bypasses to the axillary or brachial artery. Concomitant cervicodorsal sympathectomy was done in only four patients. The in-hospital graft patency rate was 93% and the long-term graft patency rate at one year and beyond was 88%.     

Versicherungsrechtliche Medizin

International Journal of Legal Medicine -     

Totally autogenous venovenous composite bypass grafts. Salvage of the almost irretrievable extremity

When a suitable single length of saphenous or arm vein is unavailable, the elderly patient with a profoundly ischemic extremity, poor runoff, and a distal outflow vessel frequently undergoes amputation. Rather than performing primary amputation or resorting to nonautogenous conduites, we used 21 different combinations of available vein segments of ipsilateral or contralateral greater saphenous, lesser saphenous, cephalic, and basilic veins as composite autogenous bypass grafts. Fifty-four extremities, of which 21 (39%) had one or more failed previous bypasses, were revascularized. Tissue necrosis necessitated operation in 74% (40 instances) and rest pain in 19% (ten instances). All grafts extended below the knee, 22% (12 grafts) to the infrageniculate popliteal artery, 78% (42 grafts) to an infrapopliteal runoff vessel, and 28% (15 grafts) to the ankle or foot. The patency rate at one month was 81%. Thrombectomy alone or with local graft repair increased the one-month patency rate to 96%. At one year, the patency and limb salvage rates were 74% and 82%, respectively.     

Verletzungen. Gewaltsamer Tod aus physikalischer Ursache

Ohne Zusammenfassung     

The transition to "in situ" vein bypass grafts

In situ saphenous vein bypass grafts were used to revascularize 109 lower extremities in 99 patients during 1984. Of those, 102 were single length grafts carried out in 53 males and 39 females with an average age of 69 and 75 years old, respectively. The expected associated risk factors were observed: smoking in 69 per cent, hypertension in 57 per cent, heart disease in 52 per cent and diabetes in 31 per cent of the patients. Grafts were performed for limb salvage in 71 patients, claudication in 30 and aneurysm in one. Single length grafts originated from the common (47), superficial (27), deep femoral (18) or popliteal (four) arteries or proximal Dacron (polyester) grafts (six); 93 per cent of the grafts were to an infrageniculate target site, while 44 per cent extended to an infrapopliteal artery and 7 per cent to the ankle. Operating time including completion angiography, which was done in every instance, was comparable to that with reversed vein grafts. The patency rate at one year was 96 per cent or 87 per cent when claudication or limb salvage was the indication for operation, and 92 per cent or 86 per cent when the distal anastomosis was to a popliteal or infrapopliteal artery. Limb salvage rates were 97 per cent at one month and 91 per cent at one year. All five amputations occurred in patients receiving infrapopliteal grafts for gangrene. The survival rate was 97 per cent at one month and 85 per cent at one year.