全文获取类型
收费全文 | 22828篇 |
免费 | 1793篇 |
国内免费 | 512篇 |
专业分类
耳鼻咽喉 | 319篇 |
儿科学 | 354篇 |
妇产科学 | 408篇 |
基础医学 | 3431篇 |
口腔科学 | 385篇 |
临床医学 | 2324篇 |
内科学 | 3747篇 |
皮肤病学 | 967篇 |
神经病学 | 1330篇 |
特种医学 | 1438篇 |
外国民族医学 | 7篇 |
外科学 | 2900篇 |
综合类 | 883篇 |
现状与发展 | 1篇 |
一般理论 | 5篇 |
预防医学 | 1309篇 |
眼科学 | 589篇 |
药学 | 2424篇 |
5篇 | |
中国医学 | 681篇 |
肿瘤学 | 1626篇 |
出版年
2023年 | 165篇 |
2022年 | 218篇 |
2021年 | 859篇 |
2020年 | 539篇 |
2019年 | 707篇 |
2018年 | 766篇 |
2017年 | 624篇 |
2016年 | 869篇 |
2015年 | 1210篇 |
2014年 | 1445篇 |
2013年 | 1473篇 |
2012年 | 2225篇 |
2011年 | 2096篇 |
2010年 | 1265篇 |
2009年 | 1032篇 |
2008年 | 1373篇 |
2007年 | 1239篇 |
2006年 | 1058篇 |
2005年 | 1062篇 |
2004年 | 804篇 |
2003年 | 717篇 |
2002年 | 637篇 |
2001年 | 350篇 |
2000年 | 364篇 |
1999年 | 329篇 |
1998年 | 157篇 |
1997年 | 143篇 |
1996年 | 104篇 |
1995年 | 98篇 |
1994年 | 71篇 |
1993年 | 61篇 |
1992年 | 111篇 |
1991年 | 89篇 |
1990年 | 84篇 |
1989年 | 65篇 |
1988年 | 67篇 |
1987年 | 62篇 |
1986年 | 54篇 |
1985年 | 61篇 |
1984年 | 45篇 |
1983年 | 59篇 |
1982年 | 20篇 |
1981年 | 20篇 |
1979年 | 37篇 |
1978年 | 30篇 |
1977年 | 23篇 |
1976年 | 21篇 |
1975年 | 18篇 |
1974年 | 20篇 |
1973年 | 27篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Xiao-Long Tang Yan-Dong Miao Deng-Hai Mi 《World journal of gastrointestinal oncology》2022,14(1):366-368
The present letter to the editor is in response to the research “Outcomes of curative liver resection for hepatocellular carcinoma in patients with cirrhosis” by Elshaarawy et al in World J Gastroenterol 2021; 13(5): 424–439. The preoperative assessment of the liver reserve function in hepatocellular carcinoma (HCC) patients with cirrhosis is crucial, and there is no universal consensus on how to assess it. Based on a retrospective study, Elshaarawy et al investigated the impact of various classical clinical indicators on liver failure and the prognosis after hepatectomy in HCC patients with cirrhosis. We recommend that we should strive to explore new appraisal indicators, such as the indocyanine green retention rate at 15 min. 相似文献
2.
Hyun Jong Choi Jong Ho Moon Yun Nah Lee Hyun Su Kim Ji Su Ha Tae Hoon Lee Sang‐Woo Cha Young Deok Cho Sang‐Heum Park 《Digestive endoscopy》2015,27(7):772-775
Direct peroral cholangioscopy (POC) using an ultra‐slim upper endoscope is one modality of POC for intraductal endoscopic evaluation and treatment of the bile duct. Choledochoduodenostomy (CDS) is one modality of biliary bypass surgery that provides a new route to the bile duct. We carried out direct POC using an ultra‐slim upper endoscope without the use of accessories in 10 patients (four sump syndromes, three bile duct strictures and three intrahepatic duct stones) previously undergoing surgical CDS. Direct POC was successful in all patients. The use of an intraductal balloon catheter was required in one patient for advancement of the endoscope into the bile duct. Distal bile ducts with sump syndromes were cleared using baskets and water irrigation under direct POC. Cholangiocarcinoma was diagnosed in one patient with hilar bile duct stricture after cholangioscopic evaluation and a targeting forceps biopsy under direct POC. Intrahepatic duct stones were successfully extracted after intraductal fragmentation under direct POC. Oozing bleeding occurred during intraductal lithotripsy but stopped spontaneously. Direct POC using an ultra‐slim upper endoscope without the assistance of accessories can easily be carried out in patients undergoing CDS. 相似文献
3.
4.
Jae Yun Ahn Jung Bae Park Sungbae Moon Jae Wan Cho Dong Ho Park 《Ophthalmic epidemiology》2020,27(2):105-114
ABSTRACT
Purpose
Work-related eye injuries have been reported with a variety of epidemiologic and clinical characteristics. We aimed to identify epidemiologic characteristics of work-related eye injuries and risk factors associated with severe injury in a large metropolitan city. 相似文献5.
Qian Li Tian-Le Ma You-Qi Qiu Wen-Qiang Cui Teng Chen Wen-Wen Zhang Jing Wang Qi-Liang Mao-Ying Wen-Li Mi Yan-Qing Wang Yu-Xia Chu 《神经科学通报》2020,36(12):1484
Trigeminal neuralgia is a debilitating condition, and the pain easily spreads to other parts of the face. Here, we established a mouse model of partial transection of the infraorbital nerve (pT-ION) and found that the Connexin 36 (Cx36) inhibitor mefloquine caused greater alleviation of pT-ION-induced cold allodynia compared to the reduction of mechanical allodynia. Mefloquine reversed the pT-ION-induced upregulation of Cx36, glutamate receptor ionotropic kainate 2 (GluK2), transient receptor potential ankyrin 1 (TRPA1), and phosphorylated extracellular signal regulated kinase (p-ERK) in the trigeminal ganglion. Cold allodynia but not mechanical allodynia induced by pT-ION or by virus-mediated overexpression of Cx36 in the trigeminal ganglion was reversed by the GluK2 antagonist NS102, and knocking down Cx36 expression in Nav1.8-expressing nociceptors by injecting virus into the orofacial skin area of Nav1.8-Cre mice attenuated cold allodynia but not mechanical allodynia. In conclusion, we show that Cx36 contributes greatly to the development of orofacial pain hypersensitivity through GluK2, TRPA1, and p-ERK signaling.Electronic supplementary materialThe online version of this article (10.1007/s12264-020-00594-4) contains supplementary material, which is available to authorized users. 相似文献
6.
7.
8.
9.
10.
Clinical clues for differential diagnosis between verruca plana and verruca plana‐like seborrheic keratosis 下载免费PDF全文
Won‐Jeong Kim Won‐Ku Lee Margaret Song Hoon‐Soo Kim Hyun‐Chang Ko Byung‐Soo Kim Moon‐Bum Kim 《The Journal of dermatology》2015,42(4):373-377
Sometimes the clinical differentiation between verruca plana (VP) and VP‐like seborrheic keratosis (SK) could be challenged. However, there have been no studies on this issue to date. The aim of this study was to elucidate clinical and dermoscopic differences between these two diseases, and also to suggest a diagnostic algorithm of VP and VP‐like SK without skin biopsy. The patients who had lesions clinically considered as VP or VP‐like SK were the target of our study. We took clinical and dermoscopic photos with informed consent and conducted a questionnaire. All patients had their diagnoses confirmed by biopsy. Thirty‐three patients were enrolled in our study. Seventeen patients were finally diagnosed with VP (51.5%) and 16 patients with VP‐like SK (48.5%). In clinical findings, VP‐like SK showed significantly more scattered distribution than VP (P = 0.039), which exhibited more clustered or grouped distribution (P = 0.039). In dermoscopic findings, brain‐like appearance was more commonly observed in VP‐like SK (P = 0.003) whereas VP showed more red dots or globular vessels (P = 0.017) and even‐colored light brown to yellow patch (P < 0.001). Sex, onset age, the size of each lesion, location, color and shape showed no significant differences between them (P > 0.05). Based on our results, we suggest a diagnostic algorithm using Koebner's phenomenon, dermoscopic findings, distribution of each lesion and biopsy for multiple VP‐like lesions in adults, and we think it will be a very useful diagnostic tool in daily clinical dermatological practice. 相似文献