Features of diagnosis and clinical course of penetrating injuries of the posterior pole of the eye

Seventeen patients with penetrating injuries in the posterior pole caused by mechanical trauma of the eye were analyzed clinically; such injuries were characterized by the development of the most severe complications, which led to eye loss. An incomplete sealing of the penetrating trauma of the eye fibrous capsule localized in the posterior sclera section was the main reason that predetermined a trauma outcome; it can be rarely diagnosed and is difficult for surgical treatment. Computer tomography, which makes it possible to detect and localize the discussed pathology, is the most informative method in diagnosing the posterior pole. The organ-saving effect and process stabilization were ensured in 98.5% of patients owing to the use of a set of diagnostic pre- and intraoperative techniques.     

Expression of cytokine genes in blood mononuclear cells in women with pyoinflammatory diseases of adnexa uteri

Production of interleukin, interferon-, and transforming growth ₂-factor mRNA in peripheral blood mononuclear cells was studied in women with pyoinflammatory diseases of adnexa uteri. Predominant expression of Th1 proinflammatory cytokine genes in patients was demonstrated. Production of interleukins 4 and 8 mRNA decreased 200- and 60-fold, respectively, in comparison with that in healthy women. One month and a half after extirpation of fallopian tubes the cytokine production in blood mononuclear cells shifted towards antiinflammatory cytokines, expression of interleukin-8 gene returned to normal, and expression of interleukin-4 gene increased.     

Use of myelopid in the complex treatment of patients with destructive pulmonary tuberculosis

A complex immunotherapy regimen containing myelopid in combination with chemotherapeutic drugs was prescribed for 30 patients aged from 17 to 54 years and suffering from destructive pulmonary tuberculosis. It was proved that a complex treatment favored the normalization of the main immunologic indices, thus greatly increasing the efficacy of pulmonary tuberculosis patient management.