全文获取类型
收费全文 | 54426篇 |
免费 | 4551篇 |
国内免费 | 271篇 |
专业分类
耳鼻咽喉 | 504篇 |
儿科学 | 1562篇 |
妇产科学 | 1048篇 |
基础医学 | 7723篇 |
口腔科学 | 627篇 |
临床医学 | 5872篇 |
内科学 | 12027篇 |
皮肤病学 | 1033篇 |
神经病学 | 5652篇 |
特种医学 | 1794篇 |
外国民族医学 | 2篇 |
外科学 | 8918篇 |
综合类 | 386篇 |
一般理论 | 38篇 |
预防医学 | 4137篇 |
眼科学 | 644篇 |
药学 | 3262篇 |
中国医学 | 130篇 |
肿瘤学 | 3889篇 |
出版年
2023年 | 212篇 |
2022年 | 169篇 |
2021年 | 990篇 |
2020年 | 785篇 |
2019年 | 1351篇 |
2018年 | 1522篇 |
2017年 | 1217篇 |
2016年 | 1245篇 |
2015年 | 1533篇 |
2014年 | 1964篇 |
2013年 | 2735篇 |
2012年 | 3655篇 |
2011年 | 3970篇 |
2010年 | 2410篇 |
2009年 | 2278篇 |
2008年 | 3441篇 |
2007年 | 3600篇 |
2006年 | 3424篇 |
2005年 | 3533篇 |
2004年 | 3273篇 |
2003年 | 3285篇 |
2002年 | 3336篇 |
2001年 | 507篇 |
2000年 | 413篇 |
1999年 | 538篇 |
1998年 | 682篇 |
1997年 | 658篇 |
1996年 | 493篇 |
1995年 | 510篇 |
1994年 | 407篇 |
1993年 | 395篇 |
1992年 | 297篇 |
1991年 | 291篇 |
1990年 | 267篇 |
1989年 | 215篇 |
1988年 | 225篇 |
1987年 | 210篇 |
1986年 | 237篇 |
1985年 | 209篇 |
1984年 | 233篇 |
1983年 | 201篇 |
1982年 | 263篇 |
1981年 | 243篇 |
1980年 | 228篇 |
1979年 | 144篇 |
1978年 | 141篇 |
1977年 | 124篇 |
1976年 | 108篇 |
1975年 | 95篇 |
1972年 | 91篇 |
排序方式: 共有10000条查询结果,搜索用时 468 毫秒
1.
Evelyne Harkemanne Jean‐Louis Dargent Pierre‐Paul Roquet‐Gravy Audrey Bulinckx 《Pediatric dermatology》2019,36(3):365-367
We report a case of benign lymphoplasmacytic plaque (LPP) in a child. These asymptomatic erythematous papulonodular lesions are an emerging clinicopathological entity. Herein, we describe a previously unreported site for LPP lesions, namely, the volar wrist and the distal ipsilateral palm. 相似文献
2.
Jean‐Franois Etter 《Addiction (Abingdon, England)》2019,114(12):2252-2256
3.
Ingmar Fleps Pierre Guy Stephen J Ferguson Peter A Cripton Benedikt Helgason 《Journal of bone and mineral research》2019,34(10):1837-1850
The majority of hip fractures in the elderly are the result of a fall from standing or from a lower height. Current injury models focus mostly on femur strength while neglecting subject-specific loading. This article presents an injury modeling strategy for hip fractures related to sideways falls that takes subject-specific impact loading into account. Finite element models (FEMs) of the human body were used to predict the experienced load and the femoral strength in a single model. We validated these models for their predicted peak force, effective pelvic stiffness, and fracture status against matching ex vivo sideways fall impacts (n = 11) with a trochanter velocity of 3.1 m/s. Furthermore, they were compared to sideways impacts of volunteers with lower impact velocities that were previously conducted by other groups. Good agreement was found between the ex vivo experiments and the FEMs with respect to peak force (root mean square error [RMSE] = 10.7%, R2 = 0.85) and effective pelvic stiffness (R2 = 0.92, RMSE = 12.9%). The FEMs were predictive of the fracture status for 10 out of 11 specimens. Compared to the volunteer experiments from low height, the FEMs overestimated the peak force by 25% for low BMI subjects and 8% for high BMI subjects. The effective pelvic stiffness values that were derived from the FEMs were comparable to those derived from impacts with volunteers. The force attenuation from the impact surface to the femur ranged between 27% and 54% and was highly dependent on soft tissue thickness (R2 = 0.86). The energy balance in the FEMS showed that at the time of peak force 79% to 93% of the total energy is either kinetic or was transformed to soft tissue deformation. The presented FEMs allow for direct discrimination between fracture and nonfracture outcome for sideways falls and bridge the gap between impact testing with volunteers and impact conditions representative of real life falls. © 2019 American Society for Bone and Mineral Research. 相似文献
4.
5.
6.
Pierre Tiberghien Xavier de Lamballerie Pascal Morel Pierre Gallian Karine Lacombe Yazdan Yazdanpanah 《Vox sanguinis》2020,115(6):488-494
Plasma provided by COVID-19 convalescent patients may provide therapeutic relief as the number of COVID-19 cases escalates steeply worldwide. Prior findings in various viral respiratory diseases including SARS-CoV-related pneumonia suggest that convalescent plasma can reduce mortality, although formal proof of efficacy is still lacking. By reducing viral spread early on, such an approach may possibly downplay subsequent immunopathology. Identifying, collecting, qualifying and preparing plasma from convalescent patients with adequate SARS-CoV-2-neutralizing Ab titres in an acute crisis setting may be challenging, although well within the remit of most blood establishments. Careful clinical evaluation should allow to quickly establish whether such passive immunotherapy, administered at early phases of the disease in patients at high risk of deleterious evolution, may reduce the frequency of patient deterioration, and thereby COVID-19 mortality. 相似文献
7.
8.
Marcel Toussaint Raymond J. Gilles Noura Azzabou Benjamin Marty Alexandre Vignaud Andreas Greiser Pierre G. Carlier 《Medicine》2015,94(43)
Delayed contrast enhancement after injection of a gadolinium-chelate (Gd-chelate) is a reference imaging method to detect myocardial tissue changes. Its localization within the thickness of the myocardial wall allows differentiating various pathological processes such as myocardial infarction (MI), inflammatory myocarditis, and cardiomyopathies. The aim of the study was first to characterize benign myocarditis using quantitative delayed-enhancement imaging and then to investigate whether the measure of the extracellular volume fraction (ECV) can be used to discriminate between MI and myocarditis.In 6 patients with acute benign myocarditis (32.2 ± 13.8 year-old, subepicardial late gadolinium enhancement [LGE]) and 18 patients with MI (52.3 ± 10.9 year-old, subendocardial/transmural LGE), myocardial T1 was determined using the Modified Look-Locker Imaging (MOLLI) sequence at 3 Tesla before and after Gd-chelate injection. T1 values were compared in LGE and normal regions of the myocardium. The myocardial T1 values were normalized to the T1 of blood, and the ECV was calculated from T1 values of myocardium and blood pre- and post-Gd injection.In both myocarditis and MI, the T1 was lower in LGE regions than in normal regions of the left ventricle. T1 of LGE areas was significantly higher in myocarditis than in MI (446.8 ± 45.8 vs 360.5 ± 66.9 ms, P = 0.003) and ECV was lower in myocarditis than in MI (34.5 ± 3.3 vs 53.8 ± 13.0 %, P = 0.004).Both inflammatory process and chronic fibrosis induce LGE (subepicardial in myocarditis and subendocardial in MI). The present study demonstrates that the determination of T1 and ECV is able to differentiate the 2 histological patterns.Further investigation will indicate whether the severity of ECV changes might help refine the predictive risk of LGE in myocarditis. 相似文献
9.
10.
The National DMEFP Conference Team which consists of the following authors Charlene M. Dewey Teri L. Turner Linda Perkowski Jean Bailey Larry D. Gruppen 《Medical teacher》2016,38(2):141-149
Medical education fellowship programs (MEFPs) are a form of faculty development contributing to an organization’s educational mission and participants’ career development. Building an MEFP requires a systematic design, implementation, and evaluation approach which aligns institutional and individual faculty goals. Implementing an MEFP requires a team of committed individuals who provide expertise, guidance, and mentoring. Qualified MEFP directors should utilize instructional methods that promote individual and institutional short and long term growth. Directors must balance the use of traditional design, implementation, and evaluation methodologies with advancing trends that may support or threaten the acceptability and sustainability of the program. Drawing on the expertise of 28 MEFP directors, we provide twelve tips as a guide to those implementing, sustaining, and/or growing a successful MEFP whose value is demonstrated by its impacts on participants, learners, patients, teaching faculty, institutions, the greater medical education community, and the population’s health. 相似文献