全文获取类型
收费全文 | 2424篇 |
免费 | 336篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 121篇 |
妇产科学 | 45篇 |
基础医学 | 356篇 |
口腔科学 | 43篇 |
临床医学 | 194篇 |
内科学 | 516篇 |
皮肤病学 | 35篇 |
神经病学 | 191篇 |
特种医学 | 313篇 |
外科学 | 276篇 |
综合类 | 111篇 |
一般理论 | 1篇 |
预防医学 | 210篇 |
眼科学 | 16篇 |
药学 | 160篇 |
1篇 | |
中国医学 | 4篇 |
肿瘤学 | 161篇 |
出版年
2021年 | 29篇 |
2020年 | 21篇 |
2019年 | 27篇 |
2018年 | 37篇 |
2017年 | 40篇 |
2016年 | 28篇 |
2015年 | 41篇 |
2014年 | 50篇 |
2013年 | 64篇 |
2012年 | 76篇 |
2011年 | 98篇 |
2010年 | 66篇 |
2009年 | 72篇 |
2008年 | 85篇 |
2007年 | 97篇 |
2006年 | 103篇 |
2005年 | 88篇 |
2004年 | 74篇 |
2003年 | 96篇 |
2002年 | 74篇 |
2001年 | 79篇 |
2000年 | 80篇 |
1999年 | 73篇 |
1998年 | 77篇 |
1997年 | 72篇 |
1996年 | 73篇 |
1995年 | 52篇 |
1994年 | 50篇 |
1993年 | 59篇 |
1992年 | 71篇 |
1991年 | 63篇 |
1990年 | 70篇 |
1989年 | 72篇 |
1988年 | 67篇 |
1987年 | 62篇 |
1986年 | 45篇 |
1985年 | 38篇 |
1984年 | 45篇 |
1983年 | 27篇 |
1982年 | 25篇 |
1981年 | 28篇 |
1980年 | 26篇 |
1979年 | 31篇 |
1978年 | 18篇 |
1977年 | 20篇 |
1976年 | 27篇 |
1975年 | 22篇 |
1974年 | 17篇 |
1973年 | 18篇 |
1971年 | 12篇 |
排序方式: 共有2769条查询结果,搜索用时 109 毫秒
1.
Uptake of iodine-123 MIBG by pheochromocytomas, paragangliomas, and neuroblastomas: a histopathological comparison 总被引:2,自引:0,他引:2
J Bomanji D A Levison W D Flatman T Horne P M Bouloux G Ross K E Britton G M Besser 《Journal of nuclear medicine》1987,28(6):973-978
The percentage uptake of [123I]metaiodobenzylguanidine (MIBG) by tumors of the paraganglion system is compared with the number of neurosecretory granules (assessed by both light and electron microscopy) in the subsequently resected tumors in six patients. Iodine-123 MIBG was injected intravenously; the tumor uptake of [123I]MIBG varied between 0.001% and 0.14% of the injected dose per gram of tumor tissue at 22 hr. The number of neurosecretory granules in tissue sections was scored on a scale of I-III. A direct proportional correlation was found between the percentage uptake of [123I]MIBG by the tumor and the number of neurosecretory granules in the tissue sections but not with plasma or urinary catecholamines. This technique for imaging reflects the storage status of the tumor better than plasma and urinary catecholamine measurements. 相似文献
2.
The requirements, problems and progress of radioimmunotherapy in the management of certain malignancies are described. The future prospects using a two- or three-stage approach are promising. 相似文献
3.
Israel Liberzon Stephan F Taylor K Luan Phan Jennifer C Britton Lorraine M Fig Joshua A Bueller Robert A Koeppe Jon-Kar Zubieta 《Neuropsychopharmacology》2007,61(9):1030-1038
BACKGROUND: Functional neuroimaging studies have detected abnormal limbic and paralimbic activation to emotional probes in posttraumatic stress disorder (PTSD), but few studies have examined neurochemical mechanisms that underlie functional alterations in regional cerebral blood flow. The mu-opioid neurotransmitter system, implicated in responses to stress and suppression of pain, is distributed in and is thought to regulate the function of brain regions that are implicated in affective processing. METHODS: Here we examined the micro-opioid system with positron emission tomography and the micro-opioid receptor-selective radiotracer [11C] carfentanil in 16 male patients with PTSD and two non-PTSD male control groups, with (n = 14) and without combat exposure (n = 15). Differences in micro-opioid receptor binding potential (BP2) were detected within discrete limbic and paralimbic regions. RESULTS: Relative to healthy controls, both trauma-exposed groups had lower micro-opioid receptor BP2 in extended amygdala, nucleus accumbens, and dorsal frontal and insular cortex but had higher BP2 in the orbitofrontal cortex. PTSD patients exhibited reduced BP2 in anterior cingulate cortex compared with both control groups. Micro-opioid receptor BP2 in combat-exposed subjects without PTSD was lower in the amygdala but higher in the orbitofrontal cortex compared with both PTSD patients and healthy controls. CONCLUSIONS: These findings differentiate the general response of the micro-opioid system to trauma from more specific changes associated with PTSD. 相似文献
4.
5.
6.
De Leo V; Morgante G; Lanzetta D; D'Antona D; Bertieri RS 《Human reproduction (Oxford, England)》1997,12(2):357-360
We report the results of administration of danazol after suspension of
gonadotrophin-releasing hormone analogue (GnRHa) therapy for uterine
myomas. A total of 21 women with uterine myomas was treated with 100 mg
danazol for 6 months after GnRHa therapy. Uterine volume and endocrine
status were monitored monthly by ultrasound and assay of plasma
gonadotrophins, oestradiol and progesterone. The results show a rebound of
uterine volume about 30% less than in controls at the end of danazol
therapy. Menstrual cyclicity returned after 65 +/- 3 days in 16 subjects
and five patients remained amenorrhoeic. Hormone assays confirmed renewed
ovarian function in the women whose menstrual periods returned. Bone
mineral content was substantially reduced during GnRHa treatment but
improved significantly during danazol therapy even in the women who
remained amenorrhoeic. These results show the utility of danazol in
prolonging the therapeutic effects of GnRHa. The mechanism by which danazol
inhibits rebound of uterine volume may be due to its antiprogesterone
effects on uterine myomas.
相似文献
7.
8.
Sylvia Mitchell Veronica A. Bradley John L. Welch Peter G. Britton 《Brain injury : [BI]》1990,4(3):273-279
This study reports on the efficacy of a 'coma arousal procedure'. This procedure involved a programme of vigorous sensory stimulation administered to comatose patients by relatives using Comakits. An experimental group of 12 severely head-injured patients received the coma arousal procedure while a matched control group did not. Total duration of coma and weekly Glasgow Coma Scale Scores were recorded for the two groups. Results indicate that the total duration of coma was significantly shorter and that coma lightened more rapidly for the experimental group. 相似文献
9.
10.