Evaluation of four elastomeric interocclusal recording materials

Background: The fabrication of dental prosthesis requires the transfer of interocclusal records from patient's mouth to semiadjustable articulators using different kinds of recording media. Any inaccuracy in these interocclusal records leads to occlusal errors in the final prosthesis. This study was conducted to evaluate the dimensional changes occurring in the interocclusal recording material over a given period of time and the material's resistance to compression during the cast mounting on the articulator.     

Dental health service utilization by children seen at the University College Hospital-an update.

Asymptomatic hospital visits have been generally accepted as health behaviour that should be encouraged, although some factors have been identified as factors affecting compliance and attendance. A three years prospective study of the pattern of dental clinic attendance of children seen at the University college Hospital Ibadan was carried out between January 2001-December 2003. A total of 875 children comprising of 421 (48.1%) males and 454 (51.89%) females formed subjects for the study. Results showed that the modal age of presentation was 6-10yers. 88.8% of the children had symptomatic visits while 11.2% had asymptomatic visits and dental caries and its sequel were the frequently diagnosed symptoms. 67.8% of the symptomatic cases required extraction of their badly broken down teeth due to their late presentations at the clinic. Over 80% of the children with asymptomatic visits required only oral prophylaxis. In conclusion, an early age at presentation and asymptomatic visits are health behaviours that should be encouraged through regular dental health education to parents especially mothers.     

7β-(6-取代-2-喹诺酮-3-乙酰氨基)头孢菌素的合成

以6-取代-2-喹诺酮-3-乙酸为侧链,用CDI法和潘化酯法与7-ADCA,7-ACA,7-ACT,和7-ACD缩合,合成了16个新的7β-(6-取代-2-喹诺酮-3-乙酰氨基)头孢菌素类化合物,通过溶媒转提,葡聚糖凝胶(Sephadex LH-20)柱层析及离心薄层层析分离精制,得到纯品。初步体外抑菌试验表明:新化合物对革兰氏阳性及某些阴性菌具有高度敏感性。大多数化合物对所试试验菌的抗菌活性与头孢唑啉和青霉素G钠相当,有些比它们还强。     

亮氨酸脑啡肽的电子结构及构效关系研究

对亮氨酸脑啡肽进行了量子化学(INDO)计算,研究其电子结构特征,讨论其活性部位、作用机理及构效关系。同吗啡和R31833进行了活性部位的电子结构与空间结构比较,推断它们的活性药效结构具有共同特点,与阿片受体相互作用时作用方式相同,作用部位有对应关系,因而具有相同的药理性质。