An improved method for measurement of change in skin roughness caused by cleansing products under mild application conditions

Background: The aim of this study was to develop a method for the evaluation of subtle change in skin roughness caused by cleansing products under mild application conditions using a non‐invasive three‐dimensional (3D) analysis system. Methods: A double‐blind comparative study of the modified soap chamber test was performed using two soap bars and a syndet bar. Skin changes were evaluated by visual scoring [mean cumulative irritation index (MCII)] and by bioengineering measurements [transepidermal water loss (TEWL), skin capacitance, and skin surface roughness]. Results: MCII of the syndet bar was statistically higher than that of one soap bar, and TEWL increase after application of the syndet bar was statistically higher than that of both soap bars. Skin capacitance decreased significantly only after application of the syndet bar. The change in the average roughness of the skin surface was significantly greater after the application of the syndet bar than with classic soap bars. Conclusion: A simple, fast, and objective evaluation of skin surface topography was performed using a modified soap chamber test and a non‐invasive 3D analysis system. The results suggest that measurement of skin roughness using a non‐invasive 3D analysis system might be a good method for the evaluation of a subtle change caused by cleansing products under mild application conditions.     

Relever ensemble les nouveaux défis de la lutte contre les cancers

The “États Généraux du Cancer” held in 1998 paved the way for new legislative systems, allowing patients to receive appropriate care in accordance with their rights and the ethics of care. Advances related to the two national cancer plans as well as the continuous improvement of these systems allow optimizing the organization models and the quality of the care pathway of cancer patients. This care pathway is complex, and requires a proper coordination of homecare and hospital professionals whose cultures must converge to meet the needs of the patients and the estimated burden of care anticipated through the personalized care plan. So, the general practitioner will base his action on hospital homecare services and home networks where supportive care is provided. Finally, the quality of care requires a proactive approach, seeking anticipated instructions and, within each institution, a managerial and organizational paradigm shift. This last point reminds the necessary teamwork and multidisciplinary time and takes into account the quality of work life of healthcare professionals.     

膈神经与肋间神经移位修复臂丛神经根性撕脱伤

BACKGROUND: Phrenic nerve transfer and intercostal nerve transfer are the accepted surgery strategies for the treatment of brachial plexus root avulsion injuries; however, which surgery is more suitable for the repair remains inconclusive. OBJECTIVE: To observe the treatment outcomes of brachial plexus root avulsion injuries by transferring the phrenic nerve to the anterior division of the upper trunk of brachial plexus and the intercostal nerve to the musculocutaneous nerve. METHODS: Twenty patients with brachial plexus root avulsion injuries were included. Among them, 9 were treated with phrenic nerve transfer to the anterior division of the upper trunk of brachial plexus (phrenic nerve transfer group), and 11 were treated with intercostal nerve transfer to the musculocutaneous nerve (intercostal nerve transfer group). Postoperative follow-up ranged from 15 to 36 months. Incision length, blood loss, and operation time were recorded. Muscle strength of the biceps and elbow flexion angle were evaluated. The repair outcome was evaluated by assessing the functional recovery of musculocutaneous nerve according to the criteria issued by the Branch of Hand Surgery of Chinese Medicine Association, and the excellent and good rate was calculated. RESULTS AND CONCLUSION: The excellent and good rate was 66.7% and 63.6%, respectively, in phrenic nerve transfer group and intercostal nerve transfer group, which is not significantly different between both groups (P > 0.05). Smaller length of operation incision, reduced blood loss, and shorter operation time were found in the phrenic nerve transfer group. Two and three patients in bad recovery were in phrenic nerve transfer and intercostal nerve transfer groups, respectively. These findings suggest that the two kinds of surgery strategies for the repair of brachial plexus root avulsion injuries can obtain good results in the functional recovery of elbow flexion. Phrenic nerve transfer exerts superiorities in operation incision, blood loss and operation time. 中国组织工程研究杂志出版内容重点：组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松;组织工程     

血小板-淋巴细胞比值与冠状动脉病变复杂性的相关分析

目的:探讨血小板-淋巴细胞比值（PLR）与冠状动脉病变复杂性的相关性及临床意义。方法:纳入天津市胸科医院就诊的急性冠脉综合征（ACS）患者,检测血常规和生化指标,行冠脉造影后计算SYNTAX积分,根据SYNTAX积分分为:SYNTAX低值组（SYNTAX＜23）和SYNTAX中高值组（SYNTAX≥23）。结果:与SYNTAX低值组相比,SYNTAX中高值组血糖、肌酐、尿酸、低密度脂蛋白、白细胞计数、血小板计数和PLR均升高,而淋巴细胞计数减低,差异具有统计学意义（P＜0.05）。应用多因素Logistic回归分析显示PLR、年龄、糖尿病、既往心肌梗塞史、白细胞、LDL与SYNTAX积分显著相关（P＜0.05）。结论:入院时PLR与急性冠脉综合征患者冠脉复杂性显著相关,提示PLR增加是急性冠脉综合征患者SYNTAX积分较高的独立预测因素。