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1.
NeJhaddadgar Nazila Ziapour Arash Zakkipour Ghader Abbas Jaffar Abolfathi Mitra Shabani Masoud 《Zeitschrift fur Gesundheitswissenschaften》2022,30(5):1301-1306
Journal of Public Health - Screening services for early detection of patients is one of the important capabilities of the health system with a proper referral system. In the crisis of respiratory... 相似文献
2.
Verya Daeichin Deep Bera Shreyas Raghunathan Maysam Shabani Motlagh Zhao Chen Chao Chen Emile Noothout Hendrik J. Vos Michiel Pertijs Johan G. Bosch Nico de Jong Martin Verweij 《Ultrasound in medicine & biology》2018,44(10):2143-2154
This paper presents the design, fabrication and characterization of a miniature PZT-on-CMOS matrix transducer for real-time pediatric 3-dimensional (3D) transesophageal echocardiography (TEE). This 3D TEE probe consists of a 32?×?32 array of PZT elements integrated on top of an Application Specific Integrated Circuit (ASIC). We propose a partitioned transmit/receive array architecture wherein the 8?×?8 transmitter elements, located at the centre of the array, are directly wired out and the remaining receive elements are grouped into 96 sub-arrays of 3?×?3 elements. The echoes received by these sub-groups are locally processed by micro-beamformer circuits in the ASIC that allow pre-steering up to ±37°. The PZT-on-CMOS matrix transducer has been characterized acoustically and has a centre frequency of 5.8 MHz, -6 dB bandwidth of 67%, a transmit efficiency of 6 kPa/V at 30 mm, and a receive dynamic range of 85 dB with minimum and maximum detectable pressures of 5 Pa and 84 kPa respectively. The properties are very suitable for a miniature pediatric real-time 3D TEE probe. 相似文献
3.
Erythropoietin attenuates motor impairments induced by bilateral renal ischemia/reperfusion in rats 下载免费PDF全文
Mahshid Tahamtan Seyed M.S. Moosavi Vahid Sheibani Mohsen Nayebpour Saeed Esmaeili‐Mahani Mohammad Shabani 《Fundamental & clinical pharmacology》2016,30(6):502-510
Neurologic sequelae remain a common and destructive problem in patients with acute kidney injury. The objective of this study was to evaluate the possible neuroprotective effect of erythropoietin (EPO) on motor impairments following bilateral renal ischemia (BRI) in two time points after reperfusion: short term (24 h) and long term (1 week). Male Wistar rats underwent BRI or sham surgery. EPO or saline administration was performed 30 min before surgery (1000 U/kg, i.p.). Explorative behaviors and motor function of the rats were evaluated by open field, rotarod, and wire grip tests. Plasma concentrations of blood urea nitrogen (BUN) and creatinine (Cr) were significantly enhanced in BRI rats 24 h after reperfusion. BRI group had only an increased level of BUN but not Cr 1 week after reperfusion. Impairment of balance function by BRI was not reversed by EPO 24 h after reperfusion, but counteracted 7 days after renal ischemia. Muscle strength had no significant differences between the groups. BRI group had a decrease in locomotor activity, and EPO could not reverse this reduction in both time points of the experiment. Although EPO could not be offered as a potential neuroprotective agent in the treatment of motor dysfunctions induced by BRI, it could be effective against balance dysfunction 1 week after renal ischemia. 相似文献
4.
Mehdi Esfandyari-Manesh Seyed Hossein Mostafavi Reza Faridi Majidi Mona Noori Koopaei Nazanin Shabani Ravari Mohsen Amini Behrad Darvishi Seyed Nasser Ostad Fatemeh Atyabi Rassoul Dinarvand 《Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences》2015,23(1)
Background
Nanoparticles (NPs) play an important role in anticancer delivery systems. Surface modified NPs with hydrophilic polymers such as human serum albumin (HSA) have long half-life in the blood circulation system.Methods
The method of modified nanoprecipitation was utilized for encapsulation of paclitaxel (PTX) in poly (lactic-co-glycolic acid) (PLGA). Para-maleimide benzoic hydrazide was conjugated to PLGA for the surface modifications of PLGA NPs, and then HSA was attached on the surface of prepared NPs by maleimide attachment to thiol groups (cysteines) of albumin. The application of HSA provides for the longer blood circulation of stealth NPs due to their escape from reticuloendothelial system (RES). Then the physicochemical properties of NPs like surface morphology, size, zeta potential, and in-vitro drug release were analyzed.Results
The particle size of NPs ranged from 170 to 190 nm and increased about 20–30 nm after HSA conjugation. The zeta potential was about -6 mV and it decreased further after HSA conjugation. The HSA conjugation in prepared NPs was proved by Fourier transform infrared (FT-IR) spectroscopy, faster degradation of HSA in Differential scanning calorimetry (DSC) characterization, and other evidences such as the increasing in size and the decreasing in zeta potential. The PTX released in a biphasic mode for all colloidal suspensions. A sustained release profile for approximately 33 days was detected after a burst effect of the loaded drug. The in vitro cytotoxicity evaluation also indicated that the HSA NPs are more cytotoxic than plain NPs.Conclusions
HSA decoration of PLGA NPs may be a suitable method for longer blood circulation of NPs. 相似文献5.
Razavi Yasaman Keyhanfar Fariborz Haghparast Abbas Shabani Ronak Mehdizadeh Mehdi 《Metabolic brain disease》2021,36(6):1381-1390
Metabolic Brain Disease - Chronic methamphetamine (meth) abuse can lead to certain deficits in the hippocampal function by affecting the hippocampal neurogenesis and plasticity. To determine... 相似文献
6.
Negin Badihian Roya Riahi Mostafa Qorbani Mohammad Esmaeil Motlagh Ramin Heshmat Roya Kelishadi 《Journal of clinical hypertension (Greenwich, Conn.)》2020,22(8):1434-1441
Although blood pressure (BP) tracks from childhood to adulthood, and the prevalence of pediatric primary hypertension is increasing, related determinants are not well understood. The role of noise pollution and psychological distress in increasing BP is well documented in adults, but it remains elusive in children. This study aims to investigate the association of noise annoyance and psychological distress with BP in a pediatric population. This national cross‐sectional study was conducted in 2015 on a sample of 14400 Iranian students, aged 7‐18 years. Information regarding noise annoyance and psychological distress were assessed using questionnaires, and BP values were measured. Levels of noise annoyance and psychological distress were classified based on tertiles to no/low, moderate, and high. Data of 14274 students were completed. The mean age of participants was 12.28 (0.05), with 51% boys and 71.4% urban inhabitant. Diastolic BP and mean arterial BP (MAP) had positive correlations with noise annoyance (regression coefficient: 0.028, 95 % CI: 0.005 ‐ 0.05 and 0.025, 95 % CI: 0.002 – 0.04, respectively). Participants with higher psychological distress were 15 % more likely to experience abnormally high BP compared to those with normal psychological status or mild distresses (OR: 1.15, 95 % CI: 1.003 – 1.34). Here, we found significant positive relationships between the level of noise annoyance and values of diastolic BP and MAP. Moreover, high psychological distress showed to increase the chance of abnormally high BP. The clinical impact of these findings should be assessed in further longitudinal studies. 相似文献
7.
Kazem Darvish Bastami Nariman Shabani Mohammad Reza Imanpour Majid Afkhami 《Comparative clinical pathology》2013,22(5):965-970
Fatty acid composition of ovules (ovulated oocytes) from kutum (Rutilus frisii kutum) was investigated to assess their relationship to gonad biological characteristics, larval size, fertilization, and hatching success. Forty-eight kutum were captured in the wild during the spawning season. Results revealed an inverse relationship between linoleic acid (18:2n-6) and ovule weight (P?<?0.05). Arachidonic acid (20:4n-6) and eicosapentaenoic acid (20:5n-3) contents showed a direct correlation with the number of ovules per gram (P?<?0.05); the latter had an inverse relationship with the ratio of surface to volume (P?<?0.01). There was a direct and significant correlation between docosahexaenoic acid (22:6n-3) and ovule weight (P?<?0.05). High unsaturated fatty acid levels indicated a direct relationship with egg and yolk diameters and also an inverse correlation with ovule surface to volume ratio (P?<?0.l05). Direct relationships were found between polyunsaturated fatty acids and the diameter of egg and yolk as well as the ratio of surface to volume (P?<?0.05). There was a direct correlation between saturated fatty acid content and the number of eggs (per gram) (P?<?0.01). Total lipid and weight of newly hatched larvae represented a direct relationship (P?<?0.05). Despite living in brackish water and migrating to fresh water during the reproductive season, kutum exhibited greater similarity in ovule fatty acid composition to saltwater fish than species in fresh water. Moreover, with respect to biological characteristics, this species shows more significant relationships with n-3 fatty acids than with n-6 fatty acids. 相似文献
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10.
Mansoureh Shabani Zanjani Roya Nasirzadeh Seyed-Mohammad Fereshtehnejad Ladan Yoonesi Asl Seyed-Amir Pooya Alemzadeh Sareh Askari 《Acta neurologica Belgica》2014,114(1):15-23
Gestational diabetes mellitus (GDM) is one of the most common complications in pregnancies. Evaluating other conditions, including intra uterine growth restriction and pre-eclampsia, some studies have shown significant changes in blood flow velocity of fetal middle cerebral artery (MCA). Our study is one of the few that has aimed to assess the effects of GDM on Doppler parameters of the fetal MCA and umbilical artery (UA) and to compare with normal pregnancies. This cross-sectional study was performed on 66 pregnant women, including 33 women with GDM and the others without it, in Akbar-Abadi University Hospital in Tehran, Iran during 2010–2011. Peak systolic and diastolic velocities, pulsatility index (PI), resistance index (RI) and systolic diastolic ratio (SD) were recorded in UA as well as both right and left fetal MCAs for every recruited pregnant women by means of Doppler ultrasonography. The mean gestational age at the time of examination was 34.45 (SD = 2.62) weeks in GDM group. Although all of the measured Doppler parameters had higher values in GDM pregnancies, the differences were not significant between two groups of study; except for the left fetal MCA-PI, which was significantly higher in GDM group [2.07 (SD = 0.07) vs. 1.85 (SD = 0.74), P = 0.03]. Our results show that gestational diabetes may contribute to an elevated PI in the fetal MCA. Although there is not yet strong proof for the effect of GDM on the fetal brain hemodynamics, the significant higher MCA-PI warrants more attention towards better controlling of the hyperglycemia during pregnancy. 相似文献