全文获取类型
收费全文 | 161930篇 |
免费 | 14417篇 |
国内免费 | 9618篇 |
专业分类
耳鼻咽喉 | 1691篇 |
儿科学 | 2099篇 |
妇产科学 | 1430篇 |
基础医学 | 17258篇 |
口腔科学 | 2962篇 |
临床医学 | 18427篇 |
内科学 | 23606篇 |
皮肤病学 | 2115篇 |
神经病学 | 8294篇 |
特种医学 | 7237篇 |
外国民族医学 | 59篇 |
外科学 | 18603篇 |
综合类 | 28359篇 |
现状与发展 | 33篇 |
一般理论 | 12篇 |
预防医学 | 12212篇 |
眼科学 | 3584篇 |
药学 | 16536篇 |
145篇 | |
中国医学 | 8802篇 |
肿瘤学 | 12501篇 |
出版年
2024年 | 274篇 |
2023年 | 1671篇 |
2022年 | 3157篇 |
2021年 | 7055篇 |
2020年 | 5100篇 |
2019年 | 4429篇 |
2018年 | 4794篇 |
2017年 | 4714篇 |
2016年 | 4839篇 |
2015年 | 7288篇 |
2014年 | 9230篇 |
2013年 | 9221篇 |
2012年 | 14051篇 |
2011年 | 14734篇 |
2010年 | 10850篇 |
2009年 | 9158篇 |
2008年 | 10892篇 |
2007年 | 10753篇 |
2006年 | 9732篇 |
2005年 | 8795篇 |
2004年 | 6513篇 |
2003年 | 6073篇 |
2002年 | 5235篇 |
2001年 | 3454篇 |
2000年 | 2945篇 |
1999年 | 2252篇 |
1998年 | 1359篇 |
1997年 | 1410篇 |
1996年 | 1018篇 |
1995年 | 884篇 |
1994年 | 733篇 |
1993年 | 487篇 |
1992年 | 530篇 |
1991年 | 419篇 |
1990年 | 341篇 |
1989年 | 289篇 |
1988年 | 228篇 |
1987年 | 198篇 |
1986年 | 176篇 |
1985年 | 128篇 |
1984年 | 98篇 |
1983年 | 75篇 |
1982年 | 48篇 |
1981年 | 43篇 |
1980年 | 34篇 |
1979年 | 35篇 |
1978年 | 30篇 |
1974年 | 20篇 |
1973年 | 27篇 |
1972年 | 21篇 |
排序方式: 共有10000条查询结果,搜索用时 218 毫秒
1.
2.
Journal of Behavioral Medicine - Evidence supports the use of graphic warnings to educate the public about the health harms of smoking and suggests warnings eliciting negative emotional responses... 相似文献
4.
Feng Song Li Ruipiao Wang Zhiying 《Odontology / the Society of the Nippon Dental University》2022,110(3):508-522
Odontology - To investigate the characterization and function of a novel porous osteogenic material (PLLA / DDM) containing polylactic acid and demineralized dentin matrix. The surface morphology... 相似文献
5.
6.
目的 建立苏州市肺结核发病的SARIMA模型并预测发病,为苏州市肺结核防控提供参考。方法 收集结核病信息管理系统(新)中苏州市2010年1月—2018年12月肺结核月发病数,通过时间序列分析建立SARIMA模型并预测苏州市2019年肺结核的发病情况。结果 苏州市肺结核发病数具有明显的季节周期性,每年的发病最高峰为5月,发病最低谷为2月。苏州市肺结核发病数的最佳拟合模型为SARIMA (0,1,1)×(0,1,1)12,AIC=9.590,SBC=9.644,模型参数均具有统计学意义,模型残差为白噪声序列,模型的预测值与实际值平均绝对百分比误差MAPE=7.943%,模型预测精度较高。预测苏州市2019年肺结核发病数为3 467例,月发病数平均值为289例,发病水平较2018年略有下降。结论 SARIMA(0,1,1)×(0,1,1)12模型能较好拟合出苏州市肺结核发病数的时间变化趋势,可应用于苏州市肺结核月发病数的短期预测。 相似文献
7.
Feng Wang Dachuan Wang Bingyi Tan Jun Dong Rongjie Feng Zenong Yuan Naiguo Wang 《Medicine》2015,94(39)
The present study aimed at examining the curative effect of modified posterior operation on treatment of Kümmell''s disease.About 30 patients of Kümmell''s disease with complete image and clinical data treated during June 2004 to July 2013 were conducted with anterior and posterior approaches, respectively. Kyphotic Cobb angle, fractured vertebra wedge angle, and the anterior and posterior heights of fractured vertebra were all measured through x-ray before and after operation, and the pain visual analog scale (VAS) was determined for evaluating the effect of operations. The injury and restoration of neurological function were assessed using Frankel classification.Patients in group A were treated with anterior operation, whereas group B was posterior operation. Postoperatively, VAS score, kyphotic Cobb angle, anterior vertebra height, and pathologic vertebra wedge angle were all significantly improved in patients with Kümmell''s disease receiving modified posterior operation (group B). Similar results were also observed in patients with anterior operation. The improvement of VAS and correction rate of kyphotic Cobb angle indicated equivalent effects of posterior and anterior operations. Meanwhile, alleviated neurological function damage was observed in 2 groups. Relevant factor analysis illustrated that there was no significant correlation of the severity and improvement rate of pain symptoms with age, medical history, anterior and posterior vertebra heights, kyphotic Cobb angle, and pathological vertebra wedge angle.Compared with traditional anterior approach, modified posterior operation, adopting transpedicular vertebral body grafting combined with vertebral pedicle screw fixation, could produce equivalent effects on kyphosis correction, pain relief, and improvement of neurological function in patients with Kümmell''s disease. 相似文献
8.
9.
Huang Liyan Li Wei Li Yi Song Chaoyuan Wang Pin Wang Hongchun Sun Xiulian 《Neurogenetics》2020,21(1):39-49
neurogenetics - Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disease leading to stroke and vascular dementia.... 相似文献
10.
Jiao-Tian Xu Yuan Qian Wei Wang Xiao-Xiang Chen Yang Li Yu Li Zhi-Yong Yang Xiao-Bin Song Di Lu Xing-Li Deng 《中国神经再生研究》2020,(1):112-119
Previous studies have shown that neural stem cell transplantation has the potential to treat Parkinson’s disease,but its specific mechanism of action is still unclear.Stromal cell-derived factor-1 and its receptor,chemokine receptor 4(CXCR4),are important regulators of cell migration.We speculated that the CXCR4/stromal cell-derived factor 1 axis may be involved in the therapeutic effect of neural stem cell transplantation in the treatment of Parkinson’s disease.A Parkinson’s disease rat model was injected with 6-hydroxydopamine via the right ascending nigrostriatal dopaminergic pathway,and then treated with 5μL of neural stem cell suspension(1.5×104/L)in the right substantia nigra.Rats were intraperitoneally injected once daily for 3 days with 1.25 mL/kg of the CXCR4 antagonist AMD3100 to observe changes after neural stem cell transplantation.Parkinson-like behavior in rats was detected using apomorphine-induced rotation.Immunofluorescence staining was used to determine the immunoreactivity of tyrosine hydroxylase,CXCR4,and stromal cell-derived factor-1 in the brain.Using quantitative real-time polymerase chain reaction,the mRNA expression of stromal cell-derived factor-1 and CXCR4 in the right substantia nigra were measured.In addition,western blot assays were performed to analyze the protein expression of stromal cell-derived factor-1 and CXCR4.Our results demonstrated that neural stem cell transplantation noticeably reduced apomorphine-induced rotation,increased the mRNA and protein expression of stromal cell-derived factor-1 and CXCR4 in the right substantia nigra,and enhanced the immunoreactivity of tyrosine hydroxylase,CXCR4,and stromal cell-derived factor-1 in the brain.Injection of AMD3100 inhibited the aforementioned effects.These findings suggest that the stromal cell-derived factor-1/CXCR4 axis may play a significant role in the therapeutic effect of neural stem cell transplantation in a rat model of Parkinson’s disease.This study was approved by the Animal Care and Use Committee of Kunming Medical University,China(approval No.SYXKK2015-0002)on April 1,2014. 相似文献