全文获取类型
收费全文 | 7206篇 |
免费 | 517篇 |
国内免费 | 31篇 |
专业分类
耳鼻咽喉 | 45篇 |
儿科学 | 262篇 |
妇产科学 | 160篇 |
基础医学 | 1229篇 |
口腔科学 | 103篇 |
临床医学 | 731篇 |
内科学 | 1402篇 |
皮肤病学 | 176篇 |
神经病学 | 677篇 |
特种医学 | 168篇 |
外国民族医学 | 1篇 |
外科学 | 868篇 |
综合类 | 105篇 |
一般理论 | 2篇 |
预防医学 | 673篇 |
眼科学 | 117篇 |
药学 | 426篇 |
中国医学 | 35篇 |
肿瘤学 | 574篇 |
出版年
2023年 | 34篇 |
2022年 | 31篇 |
2021年 | 142篇 |
2020年 | 102篇 |
2019年 | 134篇 |
2018年 | 155篇 |
2017年 | 123篇 |
2016年 | 141篇 |
2015年 | 174篇 |
2014年 | 202篇 |
2013年 | 281篇 |
2012年 | 487篇 |
2011年 | 462篇 |
2010年 | 268篇 |
2009年 | 275篇 |
2008年 | 441篇 |
2007年 | 475篇 |
2006年 | 518篇 |
2005年 | 448篇 |
2004年 | 443篇 |
2003年 | 407篇 |
2002年 | 398篇 |
2001年 | 142篇 |
2000年 | 110篇 |
1999年 | 91篇 |
1998年 | 116篇 |
1997年 | 87篇 |
1996年 | 77篇 |
1995年 | 84篇 |
1994年 | 55篇 |
1993年 | 62篇 |
1992年 | 44篇 |
1991年 | 50篇 |
1990年 | 50篇 |
1989年 | 39篇 |
1988年 | 41篇 |
1987年 | 35篇 |
1986年 | 45篇 |
1985年 | 51篇 |
1984年 | 33篇 |
1983年 | 39篇 |
1982年 | 26篇 |
1981年 | 22篇 |
1980年 | 30篇 |
1979年 | 26篇 |
1978年 | 21篇 |
1976年 | 14篇 |
1975年 | 15篇 |
1974年 | 21篇 |
1973年 | 18篇 |
排序方式: 共有7754条查询结果,搜索用时 15 毫秒
1.
经皮椎体成形术是一种安全有效的微创手术,腹膜后血肿是其罕见但严重的并发症。我们报告一例经皮椎体成形术RH阴性(熊猫血)患者术后并发巨大腹膜后血肿,经保守和输血等支持治疗,病人康复出院。脊柱医生应了解这种罕见但潜在致命的并发症,因为早期认识和及时预防是降低其发病率的基础。 相似文献
2.
Cromb Amandine Le Loarer Franois Sitbon Maxime Italiano Antoine Stoeckle Eberhard Buy Xavier Kind Michle 《European radiology》2020,30(5):2413-2424
European Radiology - The strongest adverse prognostic factor in myxoid/round cell liposarcomas (MRC-LPS) is the presence of a round cell component above 5% within the tumor bulk. Its identification... 相似文献
3.
4.
5.
6.
Dominique Trudel Luminita-Mihaela Avarvarei Michèle Orain Stéphane Turcotte Marie Plante Jean Grégoire Reinhild Kappelhoff David P. Labbé Dimcho Bachvarov Bernard Têtu Christopher M. Overall Isabelle Bairati 《Pathology, research and practice》2019,215(6):152369
Ovarian carcinoma is one of the most lethal malignancies, but only very few prognostic biomarkers are known. The degradome, comprising proteases, protease non-proteolytic homologues and inhibitors, have been involved in the prognosis of many cancer types, including ovarian carcinoma. The prognostic significance of the whole degradome family has not been specifically studied in high-grade serous ovarian cancer. A targeted DNA microarray known as the CLIP-CHIP microarray was used to identify potential prognostic factors in ten high-grade serous ovarian cancer women who had early recurrence (<1.6 years) or late/no recurrence after first line surgery and chemotherapy. In women with early recurrence, we identified seven upregulated genes (TMPRSS4, MASP1/3, SPC18, PSMB1, IGFBP2, CFI – encoding Complement Factor I – and MMP9) and one down-regulated gene (ADAM-10). Using immunohistochemistry, we evaluated the prognostic effect of these 8 candidate genes in an independent cohort of 112 high-grade serous ovarian cancer women. Outcomes were progression, defined according to CA-125 criteria, and death. Multivariate Cox proportional hazard regression models were done to estimate the associations between each protein and each outcome. High ADAM-10 expression (intensity of 2–3) was associated with a lower risk of progression (adjusted hazard ratio (HR): 0.51; 95% confidence interval (CI): 0.29-0.87). High complement factor I expression (intensity 2–3) was associated with a higher risk of progression (adjusted HR: 2.30, 95% CI: 1.17–4.53) and death (adjusted HR: 3.42; 95% CI: 1.72–6.79). Overall, we identified the prognostic value of two proteases, ADAM-10 and complement factor I, for high-grade serous ovarian cancer which could have clinical significance. 相似文献
7.
8.
9.
目的探讨三康胶囊对高原人体运动后一氧化氮(NO)及其合酶(NOS)、乳酸(BLA)、血氨(Ammo)的影响.方法选择进驻海拔3 700 m高原1年的10名健康青年,口服三康胶囊15 d,在服药前后分别采用功量自行车进行渐增负荷运动,测定其血清 NO、NOS、BLA及Ammo含量.结果服药后较服药前运动后NO水平[(101.02±6.49) Vs (77.10±8.11)]和NOS活性[(71.40±7.23) Vs (56.29±6.28)]均增高, BLA[(7.58±0.79)Vs (6.13±0.74)]和Ammo[(80.11±9.44)Vs (69.38±8.86)]降低,有非常显著性差异(P<0.01).结论 三康胶囊能增强高原移居者运动后NOS活性,加速乳酸清除,减缓运动疲劳的发生. 相似文献
10.
Laurence Dorne Nadir Alikacem Robert Guidoin Michle Auger 《Magnetic resonance in medicine》1995,34(4):548-554
We have used 29Si solid-state nuclear magnetic resonance (NMR) spectroscopy to study the chemical structure of the silicone gels in virgin and explanted breast prostheses. Despite evidences of alteration in the morphological appearance of the silicone gel inside the breast prosthesis, our results do not reveal changes in the chemical nature and structure of the silicone gels after implantation. In addition to the main 29Si resonance peak at ?22.26 ppm that corresponds to the resonance frequency of the D repeat unit of the polysiloxane chains, the high sensitivity of our NMR technique allows the detection of very low concentrations of silicone compounds. Within our experimental detection limit of 0.2%, no signal between ?90 ppm and ?150 ppm are observed. This indicates that no silica products are present inside the gel of the prostheses. Furthermore, our 29Si NMR spectra indicate differences in the chemical compositions of the silicone gels from different manufacturers. 相似文献