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排序方式: 共有985条查询结果,搜索用时 15 毫秒
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Isolde Hausser Wilhelm Doerr Rudolf Frey Adolf Ueberle 《Journal of cancer research and clinical oncology》1949,56(4-5):449-481
Ohne ZusammenfassungMit 24 Textabbildungen.Vorgetragen: 1. I. Hausser, Ultraschall-Arbeitstagung Erlangen, 3. 5. 49; s. Kongreßbericht. 2. W. Doerr, ebendort; infolge Erkrankung vertreten durch I. Hausser. 3. R. Frey, Deutscher Chirurgenkongreß in Frankfurt, 9. 6. 49. 相似文献
4.
Wilhelm Doerr 《Virchows Archiv : an international journal of pathology》1938,303(1):168-205
Ohne Zusammenfassung
Mit 10 Abbildungen im Text 相似文献
5.
Amniotic-fluid ingestion enhances morphine analgesia during morphine tolerance and withdrawal in rats. 总被引:1,自引:0,他引:1
Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia in rats produced by morphine injection, footshock, vaginal/cervical stimulation, and during late pregnancy. The present study was designed to investigate the effects of amniotic fluid ingestion on the characteristics of morphine dependency and withdrawal. Tail-flick latencies in Long-Evans rats were determined before and after repeated daily injections of morphine sulfate. It was found that ingestion of amniotic fluid after establishment of the morphine dependency, coupled with an injection of an otherwise ineffective dose of morphine, enhanced analgesia in morphine-dependent rats, and reversed hyperalgesia seen during withdrawal from morphine dependency. 相似文献
6.
Radiolabeled monoclonal antibody imaging (immunoscintigraphy) of colorectal cancers: current status and future perspectives. 总被引:2,自引:0,他引:2
Over the past two decades, the role of radiolabeled monoclonal antibodies has been steadily growing in clinical practice, particularly for staging and locating a variety of neoplasms. This is due largely to the availability of these products in pharmaceutical quantities as well as the relatively low incidence of adverse reactions following the intravenous administration of antibodies to patients. One particular area of oncology where radiolabeled monoclonal antibodies are most likely to play an extremely important clinical role is in the evaluation of patients with colon and rectal carcinomas. In this report, we review the current utilization of tumor-associated monoclonal antibodies in the preoperative as well as postoperative screening of patients with colorectal carcinoma. 相似文献
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Zusammenfassung
Bei einer 37 j?hrigen, bisher gesunden Patientin entwickelte sich eine über 2 Monate progrediente Dyspnoe. Radiologisch und
echokardiographisch zeigte sich eine massive Dilatation s?mtlicher Herzh?hlen mit biventrikul?ren Thromben und eine stark
herabgesetzte Kontraktilit?t. Die Endomyokardbiopsien wurden von 2 Instituten als Myokarditis eingestuft. Im weiteren Verlauf
entwickelten sich thrombembolische Komplikationen und ein therapierefrakt?res Pumpversagen, in dem die Patientin schlie?lich
verstarb. Bei der Obduktion fand sich au?er einem dilatierten 600 g schweren Herzen mit biventrikul?ren Thromben ein klinisch
bisher unbekanntes Ph?ochromozytom der linken Nebenniere. Die eingehende histologische und immunhistologische Aufarbeitung
des Herzmuskelgewebes einschlie?lich Reevaluierung der Endomyokardbiopsien führte zur Revision der ursprünglichen Diagnose:
Das Krankheitsbild der 37 j?hrigen Patientin war durch eine katecholamininduzierte dilatative Kardiomyopathie verursacht worden.
相似文献
9.
Clonal growth of tumors on tissue-specific biomatrices and correlation with organ site specificity of metastases 总被引:6,自引:0,他引:6
We have found that neoplastic transformation alters the ability of cells to grow on substrata of tissue extracts, "biomatrices", enriched in extracellular matrix. Tumor cells were able to survive and grow at lower densities and on more types of biomatrices than normal cells. When plated at high densities (greater than 10(5) cells/60 mm dish), tumor cells attached with equal efficiency and grew at similar rates and to equivalent saturation densities on biomatrices derived from all tissues. However, at low (10(2)-10(4)/60-mm dish) seeding densities, the tumor cells grew only on certain types of biomatrix. For the various hepatoma and mammary carcinoma cell lines tested, the tissue specificity in clonal growth on biomatrices correlated with their organ site specificity for metastasis in vivo in immunosuppressed, athymic nude mice. Analysis of the effects of purified matrix components (adhesion proteins, collagens, glycosaminoglycans) indicated that only the glycosaminoglycans influenced density-dependent survival and growth of tumor cells with effects that differed with respect to the cell's metastatic potential. The results indicate that the ability of tumor cells to colonize specific tissues represents, in part, regulation of low density survival and growth by extracellular matrix and are suggestive that one of the matrix components responsible may be proteoglycans or their glycosaminoglycan chains. 相似文献
10.
Calcium ionophore-induced acrosome reaction correlates with fertilization rates in vitro in patients with teratozoospermic semen 总被引:5,自引:3,他引:5
The aim of this study was to determine the relationship between calcium
ionophore A23187-induced acrosome reaction (AR) and sperm fertilizing
ability. Semen samples remaining after preparation for standard IVF were
studied in 109 patients who had sperm concentrations > or =20 x
10(6)/ml. Ionophore-induced AR was performed on motile spermatozoa selected
by centrifugation on a Percoll gradient. Semen analysis was performed using
standard methods. Patients with higher (>50%, n = 76) fertilization
rates had significantly higher ionophore-induced AR than patients with
lower (<50%, n = 33) fertilization rates (49 +/- 14 versus 38 +/- 21%, P
< 0.05). When the data from all patients were analysed by logistic
regression, only the percentage sperm motility in insemination medium and
ionophore-induced AR were significantly related to fertilization rates.
Similar results were also obtained when the data from a subgroup of
patients with poor (<15% normal) sperm morphology were analysed.
However, when patients with normal sperm morphology > or =15% were
analysed separately, only sperm count and the percentage of spermatozoa
with progressive motility in semen were significantly related to
fertilization rates. In conclusion, ionophore- induced AR was significantly
related to fertilization rates in vitro mainly in patients with
teratozoospermic semen. Tests for ionophore- induced AR may provide
additional information about sperm fertilizing ability but may not indicate
specific defects of the physiological AR.
相似文献