全文获取类型
收费全文 | 2590篇 |
免费 | 177篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 21篇 |
儿科学 | 41篇 |
妇产科学 | 21篇 |
基础医学 | 470篇 |
口腔科学 | 80篇 |
临床医学 | 292篇 |
内科学 | 498篇 |
皮肤病学 | 44篇 |
神经病学 | 183篇 |
特种医学 | 55篇 |
外科学 | 293篇 |
综合类 | 14篇 |
预防医学 | 192篇 |
眼科学 | 21篇 |
药学 | 347篇 |
中国医学 | 5篇 |
肿瘤学 | 199篇 |
出版年
2023年 | 21篇 |
2021年 | 51篇 |
2020年 | 35篇 |
2019年 | 61篇 |
2018年 | 72篇 |
2017年 | 49篇 |
2016年 | 72篇 |
2015年 | 88篇 |
2014年 | 107篇 |
2013年 | 204篇 |
2012年 | 220篇 |
2011年 | 249篇 |
2010年 | 185篇 |
2009年 | 72篇 |
2008年 | 70篇 |
2007年 | 68篇 |
2006年 | 46篇 |
2005年 | 84篇 |
2004年 | 80篇 |
2003年 | 66篇 |
2002年 | 49篇 |
2001年 | 41篇 |
2000年 | 42篇 |
1999年 | 36篇 |
1998年 | 17篇 |
1997年 | 29篇 |
1996年 | 19篇 |
1992年 | 19篇 |
1991年 | 24篇 |
1990年 | 17篇 |
1989年 | 18篇 |
1988年 | 19篇 |
1987年 | 27篇 |
1986年 | 29篇 |
1985年 | 18篇 |
1984年 | 29篇 |
1983年 | 24篇 |
1982年 | 23篇 |
1981年 | 31篇 |
1980年 | 18篇 |
1979年 | 29篇 |
1978年 | 21篇 |
1977年 | 23篇 |
1976年 | 30篇 |
1975年 | 12篇 |
1974年 | 14篇 |
1973年 | 13篇 |
1972年 | 13篇 |
1971年 | 18篇 |
1967年 | 17篇 |
排序方式: 共有2776条查询结果,搜索用时 765 毫秒
1.
2.
Éktova L. V. Goryunova O. V. Eremina V. A. Tikhonova N. I. Medvedeva L. A. 《Pharmaceutical Chemistry Journal》2019,53(7):604-609
Pharmaceutical Chemistry Journal - Use of formylindolylacetic acid as a reagent at the stage of preparing the glycosides of bis(indolyl)furan-2,5-diones and dioxane as solvent increased yields from... 相似文献
3.
Duds Eszter Susa va Pamjav Horolma Szabolcsi Zoltn 《International journal of legal medicine》2020,134(2):487-489
International Journal of Legal Medicine - Gyula Ágner was a Royal Hungarian First Lieutenant (1st Lt.) during the World War II and died at 30 years old due to a mine shrapnel injury... 相似文献
4.
5.
6.
7.
Chelyabinsk Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. D. Ado.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 113, No. 3, pp. 299–301, March, 1992. 相似文献
8.
E. A. Érenpreisa R. A. Zirne N. D. Zaleskaya T. G. Sjakste 《Bulletin of experimental biology and medicine》1988,106(5):1605-1608
Laboratory of Chemistry of the Cancer Cell, Latvian Research Institute of Experimental and Clinical Medicine, Ministry of Health of the Latvian SSR, Riga. (Presented by Academician of the Academy of Medical Sciences of the USSR I. B. Zbarskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 106, No. 11, pp. 591–593, November, 1988. 相似文献
9.
Two hundred and ten patients with clinical evidence of heartfailure, developing after an acute myocardial infarction, wererandomized to treatment with the ß1 antagonist metoprolol50100mg b.i.d. (n=106) or the ß1 partial agonistxamoterol 100200 mg bid. (n=104). Left ventricular systolicand diastolic function were assessed with echocardiography andtransmitral Doppler cardiography before and after 3 and 12 monthsof double-blind treatment. E-point septal separation and percent left ventricular fractional shortening were used as indicesof systolic function. The ratio between peak early and latemitral diastolic flow (E/A ratio) and isovolumic relaxationtime were used as indices of diastolic function. In the xamoterol group, there was a deterioration in E-pointseptal separation (P<0·05). A difference between thetreatment groups was present both at 3 months (E-point septalseparation 11·4 vs 13·0 mm, P<0·0l,fractional short ening 271 vs 252%, P<005) and 12 months(E-point septal separation Ill vs 13·2 mm, P<0·05fractional shortening 26·9 vs 25·0%, P<0·05).E/A ratio increased in the metoprolol group (P<0·05)but not in the xamoterol group. At 3 months there was a significantdifference (0·85 vs 0·67, P<0·005 betweenthe groups but not at 12 months. In comparison with the ß1-receptor antagonist metoprolol,the ß1 partial agonist xamoterol impaired left ventricularsystolic function in patients with clinical evidence of heartfailure after an acute myocardial infarction. 相似文献
10.
Endogenous kynurenic acid disrupts prepulse inhibition. 总被引:6,自引:0,他引:6
Sophie Erhardt Lilly Schwieler Carolina Emanuelsson Mark Geyer 《Neuropsychopharmacology》2004,56(4):255-260
BACKGROUND: Recent studies show that endogenous levels of kynurenic acid (KYNA) are increased in the cerebrospinal fluid of schizophrenic patients. Prepulse inhibition (PPI) of the acoustic startle reflex is an operational measure of sensorimotor gating that is reduced in neuropsychiatric disorders, such as schizophrenia. Previous studies show that administration of N-methyl-D-aspartate (NMDA) receptor antagonists, such as phencyclidine or MK-801, leads to deficits in sensorimotor gating that mimic those observed in schizophrenic patients. METHODS: The present study examined the effects of the endogenous NMDA receptor antagonist KYNA on startle and PPI in rats. Elevation of endogenous brain levels of KYNA was achieved through intraperitoneal (IP) administration of kynurenine (100 mg/kg), the precursor of KYNA, or by intravenous administration of PNU 156561A (10 mg/kg). RESULTS: A fourfold increase in brain KYNA levels, as induced by kynurenine or PNU 156561A, significantly reduced PPI. There were no differences in startle magnitudes between control rats and drug-treated rats. The disruption of PPI was restored by administration of the antipsychotic drugs haloperidol (.2 mg/kg, IP) or clozapine (7.5 mg/kg, IP). CONCLUSIONS: The present results suggest that brain KYNA serves as an endogenous modulator of PPI and are consistent with the hypothesis that KYNA contributes to the pathophysiology of schizophrenia. 相似文献