全文获取类型
收费全文 | 5942篇 |
免费 | 504篇 |
国内免费 | 16篇 |
专业分类
耳鼻咽喉 | 55篇 |
儿科学 | 182篇 |
妇产科学 | 145篇 |
基础医学 | 843篇 |
口腔科学 | 100篇 |
临床医学 | 598篇 |
内科学 | 1072篇 |
皮肤病学 | 102篇 |
神经病学 | 561篇 |
特种医学 | 249篇 |
外科学 | 1036篇 |
综合类 | 105篇 |
一般理论 | 4篇 |
预防医学 | 527篇 |
眼科学 | 58篇 |
药学 | 321篇 |
中国医学 | 5篇 |
肿瘤学 | 499篇 |
出版年
2023年 | 32篇 |
2022年 | 30篇 |
2021年 | 132篇 |
2020年 | 86篇 |
2019年 | 148篇 |
2018年 | 166篇 |
2017年 | 109篇 |
2016年 | 138篇 |
2015年 | 147篇 |
2014年 | 191篇 |
2013年 | 284篇 |
2012年 | 410篇 |
2011年 | 401篇 |
2010年 | 207篇 |
2009年 | 204篇 |
2008年 | 322篇 |
2007年 | 355篇 |
2006年 | 274篇 |
2005年 | 256篇 |
2004年 | 256篇 |
2003年 | 218篇 |
2002年 | 220篇 |
2001年 | 143篇 |
2000年 | 140篇 |
1999年 | 131篇 |
1998年 | 53篇 |
1997年 | 60篇 |
1996年 | 44篇 |
1995年 | 53篇 |
1994年 | 38篇 |
1993年 | 31篇 |
1992年 | 101篇 |
1991年 | 88篇 |
1990年 | 111篇 |
1989年 | 93篇 |
1988年 | 74篇 |
1987年 | 76篇 |
1986年 | 81篇 |
1985年 | 63篇 |
1984年 | 53篇 |
1983年 | 41篇 |
1982年 | 31篇 |
1981年 | 28篇 |
1979年 | 40篇 |
1978年 | 29篇 |
1977年 | 21篇 |
1976年 | 22篇 |
1975年 | 22篇 |
1974年 | 30篇 |
1972年 | 21篇 |
排序方式: 共有6462条查询结果,搜索用时 46 毫秒
1.
Rupa Narayan MD Traci M. Blonquist MS Ashkan Emadi MD PhD Robert P. Hasserjian MD Meghan Burke BS Christopher Lescinskas BS Donna S. Neuberg ScD Andrew M. Brunner MD Gabriela Hobbs MD Hanno Hock MD PhD Steven L. McAfee MD Yi-Bin Chen MD Eyal Attar MD Timothy A. Graubert MD Christina Bertoli MSN Jenna A. Moran MSN Meghan K. Bergeron MSN Julia E. Foster MSN Aura Y. Ramos BSN Tina T. Som BSN Megan K. Vartanian BSN RN Jennifer L. Story LPN Kristin McGregor MS Molly Macrae BS Tanya Behnan BS Margaret C. Wey PhD Jessica Rae BSN Frederic I. Preffer PhD Patricia Lesho BA Vu H. Duong MD Mason L. Mann BA Karen K. Ballen MD Christine Connolly BS Philip C. Amrein MD Amir T. Fathi MD 《Cancer》2020,126(6):1264-1273
2.
Globally, the COVID‐19 pandemic has already led to major increases in unemployment and is expected to lead to unprecedented increases in poverty and food and nutrition insecurity, as well as poor health outcomes. Families where young children, youth, pregnant and lactating women live need to be protected against the ongoing protracted pandemic and the aftershocks that are very likely to follow for years to come. The future wellbeing of the vast majority of the world now depends on reconfiguring the current ineffective food, nutrition, health, and social protection systems to ensure food and nutrition security for all. Because food, nutrition, health, and socio‐economic outcomes are intimately inter‐linked, it is essential that we find out how to effectively address the need to reconfigure and to provide better intersecoral coordination among global and local food, health care, and social protection systems taking equity and sutainability principles into account. Implementation science research informed by complex adaptive sytems frameworks will be needed to fill in the major knowledge gaps. Not doing so will not only put the development of individuals at further risk, but also negatively impact on the development potential of entire nations and ultimately our planet. 相似文献
3.
Sumanta K. Pal MD Dean Bajorin MD Nazli Dizman MD Jean Hoffman-Censits MD David I. Quinn MD Daniel P. Petrylak MD Matthew D. Galsky MD Ulka Vaishampayan MD Ugo De Giorgi MD Sumati Gupta MD Howard A. Burris MD Harris S. Soifer PhD Gary Li PhD Hao Wang PhD Carl L. Dambkowski MD Susan Moran MD Siamak Daneshmand MD Jonathan E. Rosenberg MD 《Cancer》2020,126(11):2597-2606
4.
Sherry X Yang Richard M Simon Antoinette R Tan Diana Nguyen Sandra M Swain 《Clinical cancer research》2005,11(17):6226-6232
PURPOSE: To delineate gene expression patterns and profile changes in metastatic tumor biopsies at baseline and 1 month after treatment with the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib in patients with metastatic breast cancer. EXPERIMENTAL DESIGN: Patients were treated with 150 mg of oral erlotinib daily. Gene expression profiles were measured with Affymetrix U133A GeneChip and immunohistochemistry was used to validate microarray findings. RESULTS: Estrogen receptor (ER) status by immunohistochemistry is nearly coincided with the two major expression clusters determined by expression of genes using unsupervised hierarchical clustering analysis. One of 10 patients had an EGFR-positive tumor detected by both microarray and immunohistochemistry. In this tumor, tissue inhibitor of metalloproteinases-3 and collagen type 1 alpha 2, which are the EGF-down-regulated growth repressors, were significantly increased by erlotinib. Gene changes in EGFR-negative tumors are those of G-protein-linked and cell surface receptor-linked signaling. Gene ontology comparison analysis pretreatment and posttreatment in EGFR-negative tumors revealed biological process categories that have more genes differentially expressed than expected by chance. Among 495 gene ontology categories, the significant differed gene ontology groups include G-protein-coupled receptor protein signaling (34 genes, P = 0.002) and cell surface receptor-linked signal transduction (74 genes, P = 0.007). CONCLUSIONS: ER status reflects the major difference in gene expression pattern in metastatic breast cancer. Erlotinib had effects on genes of EGFR signaling pathway in the EGFR-positive tumor and on gene ontology biological process categories or genes that have function in signal transduction in EGFR-negative tumors. 相似文献
5.
6.
7.
J R A Duckett S Jain A Tamilselvi P A Moran D Richmond 《Journal of obstetrics and gynaecology》2004,24(7):785-793
The aim of the study was to describe the experience, current trends and management of incontinence surgery for urodynamic stress incontinence (USI) in the United Kingdom. The study was a postal questionnaire survey that was sent to a cohort of surgeons known to be performing continence surgery. The subjects addressed included the considered role of the surgeon, the total number and type of operations performed in the last year, urodynamics and physiotherapy prior to incontinence surgery, operative complications, postoperative advice and follow-up (lengths and methods). The response rate was 54%. Large variations were found in all areas. The survey provides evidence of the number of incontinence operations performed, potentially important trends and differences in the practice and management of incontinence in the United Kingdom. This survey may be helpful in making guidelines and standards for audit at regional, local and individual levels as well as recommendations for strategies to enhance professional expertise in urogynaecology in the United Kingdom. 相似文献
8.
9.
Scarlett Lin Gomez Cynthia D O'Malley Antoinette Stroup Sarah J Shema William A Satariano 《BMC cancer》2007,7(1):193
Background
Colorectal cancer, if detected early, has greater than 90% 5-year survival. However, survival has been shown to vary across racial/ethnic groups in the United States, despite the availability of early detection methods. 相似文献10.