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1.
Aura-Ctlina Mocanu Florin Miculescu George E. Stan Andreea-Mdlina Pandele Mihai Alin Pop Robert Ctlin Ciocoiu tefan Ioan Voicu Lucian-Toma Ciocan 《Materials》2021,14(9)
A successful bone-graft-controlled healing entails the development of novel products with tunable compositional and architectural features and mechanical performances and is, thereby, able to accommodate fast bone in-growth and remodeling. To this effect, graphene nanoplatelets and Luffa-fibers were chosen as mechanical reinforcement phase and sacrificial template, respectively, and incorporated into a hydroxyapatite and brushite matrix derived by marble conversion with the help of a reproducible technology. The bio-products, framed by a one-stage-addition polymer-free fabrication route, were thoroughly physico-chemically investigated (by XRD, FTIR spectroscopy, SEM, and nano-computed tomography analysis, as well as surface energy measurements and mechanical performance assessments) after sintering in air or nitrogen ambient. The experiments exposed that the coupling of a nitrogen ambient with the graphene admixing triggers, in both compact and porous samples, important structural (i.e., decomposition of β-Ca3(PO4)2 into α-Ca3(PO4)2 and α-Ca2P2O7) and morphological modifications. Certain restrictions and benefits were outlined with respect to the spatial porosity and global mechanical features of the derived bone scaffolds. Specifically, in nitrogen ambient, the graphene amount should be set to a maximum 0.25 wt.% in the case of compact products, while for the porous ones, significantly augmented compressive strengths were revealed at all graphene amounts. The sintering ambient or the graphene addition did not interfere with the Luffa ability to generate 3D-channels-arrays at high temperatures. It can be concluded that both Luffa and graphene agents act as adjuvants under nitrogen ambient, and that their incorporation-ratio can be modulated to favorably fit certain foreseeable biomedical applications. 相似文献
2.
A glycoprotein with a molecular weight of 28 000 as estimated by SDS-polyacrylamide gel electrophoresis was isolated from seeds of Luffa acutangula using a procedure that involved acetone precipitation, ion exchange chromatography on CM Sepharose CL-6B and gel filtration on Sephadex G-50. In immunodiffusion studies it was found to be immunologically distinct from abortifacient proteins isolated from other members of the Cucurbitaceae family including Momordica charantia, Momordica cochinchinensis, Trichosanthes kirilowii and Trichosanthes cucumeroides. There were some differences in amino acid composition among the proteins although there was a gross similarity. The protein from L. acutangula was capable of inducing mid-term abortion in mice and inhibiting protein synthesis in a cell-free system. 相似文献
3.
白茅根及其混淆品的鉴定研究 总被引:1,自引:0,他引:1
曹沛琴 《中国药科大学学报》1992,23(3):177-180
白茅根为常用中药,中国药典(1990年版)载白茅根为禾本科植物白茅Imperata cylindrica(L.)P. Beauv. var. major(Nees)C. E. Hubb.的根茎。味甘,性寒。有清热、凉血 相似文献
4.
茅根炭炮制工艺及质量标准研究 总被引:2,自引:0,他引:2
采用正交试验法,对茅根炭的炮制工艺进行优选。结果表明,茅根炭的最佳炮制工艺为170℃烘制16分钟,该炮制品的多种微量元素含量明显升高。 相似文献
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丝瓜皂甙的部分药效学研究 总被引:2,自引:0,他引:2
丝瓜皂甙能促进幼龄小鼠的生长,对小鼠遭受高温,缺氧,疲劳和核辐射损伤时有保护作用;并能增强小鼠腹腔巨噬细胞吞噬和促进小鼠溶血素的形成。 相似文献
7.
白茅根化学及药理研究进展 总被引:12,自引:1,他引:11
白茅根为中医传统常用中药,用作利尿和抗炎剂.本文对白茅根的化学和药理研究进展进行了综述,包括晚近自该中药中分得一些重要的化学成分如三萜类化合物、内酯、甾醇及有机酸等,以及有关其止血、利尿、抗菌和抗肝炎等活性研究. 相似文献
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9.
目的 比较不同产地白茅根的多糖含量.方法 以葡萄糖为对照品,采用苯酚-浓硫酸法比色,通过紫外可见分光光度法测定采自11个不同产地的白茅根中多糖的含量,波长为485nm.结果 该实验测定方法相对稳定,不同产地白茅根中多糖的含量存在显著性差异,其中福建邵武产地的白茅根多糖含量最高(711.45 mg/g),其次为湖北武汉产地含量(604.89 mg/g),江西新建产地含量最低(300.88 mg/g).结论 研究结果可为白茅根多糖成分合理开发,资源的利用及质量控制提供实验依据. 相似文献
10.
不同产地白茅根总酚酸的含量比较 总被引:1,自引:0,他引:1
目的比较不同产地白茅根的总酚酸含量。方法以没食子酸为对照品,采用紫外可见分光光度法测定采自11个不同产地白茅根中总酚酸的含量,检测波长为695 nm。结果不同产地白茅根中总酚酸的含量存在差异,其中产于江西九江的白茅根总酚酸含量最高(3.48 mg.g-1),其次是产于南昌的白茅根(3.09 mg.g-1),其他产地总酚酸含量也均超过了2.10 mg.g-1。结论测定方法稳定,该研究可为白茅根总酚酸的合理开发利用及质量控制提供可借鉴的依据。 相似文献