全文获取类型
收费全文 | 2011篇 |
免费 | 176篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 192篇 |
妇产科学 | 46篇 |
基础医学 | 136篇 |
口腔科学 | 56篇 |
临床医学 | 187篇 |
内科学 | 290篇 |
皮肤病学 | 15篇 |
神经病学 | 189篇 |
特种医学 | 18篇 |
外科学 | 129篇 |
综合类 | 214篇 |
预防医学 | 436篇 |
眼科学 | 44篇 |
药学 | 120篇 |
中国医学 | 66篇 |
肿瘤学 | 65篇 |
出版年
2024年 | 3篇 |
2023年 | 14篇 |
2022年 | 22篇 |
2021年 | 45篇 |
2020年 | 60篇 |
2019年 | 50篇 |
2018年 | 57篇 |
2017年 | 67篇 |
2016年 | 90篇 |
2015年 | 63篇 |
2014年 | 90篇 |
2013年 | 209篇 |
2012年 | 107篇 |
2011年 | 119篇 |
2010年 | 86篇 |
2009年 | 105篇 |
2008年 | 108篇 |
2007年 | 117篇 |
2006年 | 93篇 |
2005年 | 77篇 |
2004年 | 69篇 |
2003年 | 76篇 |
2002年 | 69篇 |
2001年 | 43篇 |
2000年 | 46篇 |
1999年 | 33篇 |
1998年 | 39篇 |
1997年 | 26篇 |
1996年 | 24篇 |
1995年 | 19篇 |
1994年 | 15篇 |
1993年 | 20篇 |
1992年 | 8篇 |
1991年 | 13篇 |
1990年 | 10篇 |
1989年 | 13篇 |
1988年 | 13篇 |
1987年 | 7篇 |
1986年 | 9篇 |
1985年 | 9篇 |
1984年 | 11篇 |
1983年 | 6篇 |
1982年 | 7篇 |
1981年 | 7篇 |
1980年 | 11篇 |
1979年 | 7篇 |
1978年 | 7篇 |
1976年 | 2篇 |
1970年 | 3篇 |
1969年 | 3篇 |
排序方式: 共有2209条查询结果,搜索用时 165 毫秒
1.
AIM/BACKGROUND: Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease of unknown aetiology. Up to 10% of patients with typical features of PBC will have additional features of autoimmune hepatitis (AIH). A subset, however, have no such features but go on to develop a 'sequential' AIH overlap syndrome. Objectives: Describe our experience with eight patients who developed AIH after the diagnosis of PBC was made. METHODS: We reviewed the charts of all PBC patients over a 9-year period (from 1996 to 2005). Only PBC patients with no features of AIH were included. RESULTS: There were 1476 patients with PBC. Of these, eight patients developed features of AIH overlap syndrome based on biochemical and histological parameters. Treatment included prednisone and azathioprine for 24 or more months. The majority of patients remained on ursodeoxycholic acid (UDCA) throughout treatment. Response to therapy was defined by improvement in enzymes, and was rapid for all patients. One patient was able to discontinue treatment with prednisone and azathioprine, while seven have continued on therapy to date. CONCLUSIONS: A 'sequential' overlap syndrome of AIH with PBC can occur. Treatment with prednisone and azathioprine may lead to a rapid improvement in aminotransferase levels. 相似文献
2.
目的:了解和探讨新生儿出生信息的分布态势及规律。方法:对本院2006年1~6月间所有新生儿出生信息进行样本分析。结果:半年间分娩的新生儿共1075例,其中死亡19例,双胞胎15例,以1028例单胎活产新生儿的出生体重、胎龄及产妇年龄作为研究样本进行分析,统计数据与传统意义上的正常胎龄和新生儿体重基本相符,胎龄、体重均值均有所提高。结论:孕产妇的健康状况和新生儿的体质均有所改善,随胎龄的增加,新生儿出生体重亦随之增加,并且,目前新生儿的整体统计体重要大于现有的临床指标,因此,应对现有的临床指标进行适当调整,重新确定低出生体重儿和巨大儿的临床指标。 相似文献
3.
Chigbu CO Iloabachie GC 《BJOG : an international journal of obstetrics and gynaecology》2007,114(10):1261-1265
Objective To investigate the prevalence, aetiology and outcomes of caesarean section refusal in pregnant women.
Design A prospective controlled study.
Setting University of Nigeria Teaching Hospital and Aghaeze Hospital, Enugu, Nigeria.
Population A total of 62 Nigerian women who declined elective caesarean section.
Method Interviewer-administered questionnaires at the time of caesarean section refusal and postdelivery. The delivery outcomes of the subjects were compared with that of a matched control group of women who accepted caesarean section.
Main outcome measures Prevalence, maternal reasons for caesarean section refusal and the resultant maternal and perinatal mortality.
Results The prevalence of caesarean section refusal was 11.6% of all caesarean deliveries. Maternal reasons for refusing caesarean section include fear of death, economic reasons, desire to experience vaginal delivery and inadequate counselling. Outcomes were significantly worse among women who refused elective caesarean section than in the controls with a maternal mortality of 15% (versus 2%, P = 0.008) and a perinatal mortality of 34% (versus 5%, P < 0.001).
Conclusion There is a high prevalence of caesarean section refusal in south-eastern Nigeria. Women declining caesareans have very poor maternal and perinatal outcomes and need extra support. 相似文献
Design A prospective controlled study.
Setting University of Nigeria Teaching Hospital and Aghaeze Hospital, Enugu, Nigeria.
Population A total of 62 Nigerian women who declined elective caesarean section.
Method Interviewer-administered questionnaires at the time of caesarean section refusal and postdelivery. The delivery outcomes of the subjects were compared with that of a matched control group of women who accepted caesarean section.
Main outcome measures Prevalence, maternal reasons for caesarean section refusal and the resultant maternal and perinatal mortality.
Results The prevalence of caesarean section refusal was 11.6% of all caesarean deliveries. Maternal reasons for refusing caesarean section include fear of death, economic reasons, desire to experience vaginal delivery and inadequate counselling. Outcomes were significantly worse among women who refused elective caesarean section than in the controls with a maternal mortality of 15% (versus 2%, P = 0.008) and a perinatal mortality of 34% (versus 5%, P < 0.001).
Conclusion There is a high prevalence of caesarean section refusal in south-eastern Nigeria. Women declining caesareans have very poor maternal and perinatal outcomes and need extra support. 相似文献
4.
5.
Summary. There is a need to bridge key gaps between high‐ and low‐income countries and individuals; between health policy and clinical practice; and between producers and users of healthcare technology and scientific evidence. The objective of this report was to perform a diagnosis of the situation in the developing world through a survey. This survey was conducted to gather specific information on various aspects related to haemophilia. Countries were chosen by their comparability in infant and adult mortality rates according to the regionalization proposed by the World Health Organization. These indicators are very sensitive to socioeconomic conditions, and have been widely used to study health inequalities. All regions, except Africa and the East Mediterranean, were represented. Africa was excluded because its indicators were not comparable. The East Mediterranean was not represented because of difficulties in contacting investigators. Twenty‐one country representatives were contacted, and 11 answered the questionnaire. Successes obtained by developing countries are based more on the skills and creativity of the local professionals than on the availability of state‐of‐the‐art technology. Frustrations were related to disease underregistration and the limited availability of treatment products. Haemophilia care in the developing world is not as fair as we would like it to be. Governments do not always cover treatment costs, and a very small percentage of the national health budgets is alotted to haemophilia care. The role of the World Federation of Hemophilia was considered crucial by all the investigators surveyed. Training programmes and supply of factor concentrates were the main contributions identified by the respondents. 相似文献
6.
高等教育自学考试是我国高等教育的重要组成部分 ,面向农村的自学考试事关我国“三农问题”、全民教育、加速实现“小康”的大局 ,其意义重大 ,任务艰巨。文章回顾了我国及广东省自学考试 2 0多年来的发展历程 ;分析了造成当前广东省农村自学考试面临困境的多种因素 ;探讨了加快广东省面向农村自学考试创新发展的途径。 相似文献
7.
Heather J. Zar Michael J. Asmus Eugene G. Weinberg 《Pediatric allergy and immunology》2002,13(3):217-222
Inhaled therapy using a metered‐dose inhaler (MDI) with attached spacer has been increasingly recognized as the optimal method for delivering asthma medication for acute attacks and chronic prophylaxis. However, in developing countries the cost and availability of commercially produced spacers limit the use of MDI‐spacer delivery systems. A 500‐ml plastic bottle has been recently adapted to function as a spacer. This article reviews the current data on the efficacy of this bottle‐spacer and discusses its advantages and limitations. It is concluded that a modified 500‐ml plastic bottle is an effective spacer; modification and use of this device should be incorporated into international guidelines for the management of children with asthma. 相似文献
8.
Jungsun Park MD PhD Naomi Hisanaga MD Yangho Kim MD MPH 《American journal of industrial medicine》2009,52(8):625-632
Many corporations move their manufacturing facilities or technologies from developed to developing countries. Stringent regulations have made it costly for industries to operate in developed, industrialized countries. In addition, labor costs are high in these countries, and there is increasing awareness among the general public of the health risks associated with industry. The relocation of hazardous industries to developing countries is driven by economic considerations: high unemployment, a cheaper labor force, lack of regulation, and poor enforcement of any existing regulations make certain countries attractive to business. The transfer of certain industries from Japan to Korea has also brought both documented occupational diseases and a new occupational disease caused by chemicals without established toxicities. Typical examples of documented occupational diseases are carbon disulfide poisoning in the rayon manufacturing industry, bladder cancer in the benzidine industry, and mesothelioma in the asbestos industry. A new occupational disease due to a chemical without established toxicities is 2‐bromopropane poisoning. These examples suggest that counter‐measures are needed to prevent the transfer of occupational health problems from a developed to a developing country. Corporate social responsibility should be emphasized, close inter‐governmental collaboration is necessary and cooperation among non‐governmental organizations is helpful. Am. J. Ind. Med. 52:625–632, 2009. © 2009 Wiley‐Liss, Inc. 相似文献
9.
M. Al-lsmaily A. AI-Khussaiby I. G. Chestnutt K. W. Stephen A. AI-Riyami M. Abbas M. Knight 《Community dentistry and oral epidemiology》1996,24(5):362-363
Abstract This study reports the first ever national oral health survey of Omani 12-year-olds. Conducted in October 1993, of the 3,435 children examined, 1,438 (41.9%) were caries-free, although regional variations ranged from 24.8% to 61.9%. Overall, the national DMFT averaged 1.53, the majority of caries experienced being in the form of untreated decay, with occlusal surfaces of first permanent molars being the most commonly involved site. Oral hygiene was poor, only 11% of those examined being scored as plaque-free. 相似文献
10.
内蒙古赤峰地区鼠疫现状和流行趋势预测及控制措施的研究 总被引:36,自引:0,他引:36
赤峰地区于1948 ̄1996年发现了16632.2km^2鼠疫自然疫源地,分布于11个旗(县、区)。目前达到控制鼠疫面积13917.8km^2,占疫源地总面积的83.68%。选取与疫源地相关的12种量经因子进行聚类分析,结果可分为:1.疫源性长存区;2.动物鼠疫间断流行区;3.鼠疫动物病控制区;4.疫源性基本消除区。同时对措施进行了探讨。 相似文献