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目的:观察中医辨证论治慢性牙周炎的临床疗效.方法:将172例患者随机分为观察组、对照组各86例.2组均给予传统牙周炎基础疗法,观察组在此基础上给予中药辨证论治.均连续治疗14天后观察2组治疗前后菌斑指数(PLI)、牙龈指数(GI)、牙周袋探诊深度(PD)等指标的变化情况及临床疗效和复发率.结果:总有效率观察组为80.23%,对照组为60.47%,2组比较差异有统计学意义(P<0.05);PD、PLI及GI治疗前后2组组内比较,差异均有统计学意义(P<0.05);治疗后组间比较,差异有统计学意义(P<0.05);复发率对照组为20.73%,观察组为3.57%,2组比较差异有统计学意义(P<0.05).结论:中医辨证论治慢性牙周炎疗效确切,不易复发.  相似文献
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A double blind, randomized, controlled study with three parallel treatment groups was done to evaluate the efficacy of a Terminalia chebula 10% mouth rinse compared with chlorhexidine 0.12% mouth rinse, applied two times daily for 2 weeks, in the treatment of dental plaque and gingivitis. Seventy‐eight patients were included in the study. The efficacy variables were periodontal indices on days 0, 7 and 14 after commencement of therapy. Twenty six patients received chlorhexidine mouth rinse, twenty six Terminalia chebula mouth rinse and twenty six received saline solution. The clinical parameters were significantly reduced by both chlorhexidine and Terminalia chebula mouth rinse although no significant difference was seen between the two groups (P > 0.05). This study demonstrated that Terminalia chebula mouth rinse is effective in reducing microbial plaque, gingival inflammation and neutralizing salivary pH. Copyright © 2013 John Wiley & Sons, Ltd.  相似文献
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Aims

Existing in vitro and in vivo data suggest that khat may have a favorable effect on periodontal microbiota. The purpose of this study was to assess the effect of khat chewing on major periodontal pathogens in subgingival plaque samples from subjects with chronic periodontitis.

Materials and methods

40 subgingival plaque samples were obtained from periodontitis and healthy sites of 10 khat chewers (40 y median age) and 10 khat non-chewers (37.5 y median age) with chronic periodontitis. Absolute and relative counts of 6 periodontal pathogens were determined in each sample using highly sensitive and specific Taqman real-time PCR assays. Data were analyzed using an ordinal regression model.

Results

Significantly more total bacteria were detected in samples from the periodontitis sites of the khat chewers (OR = 20). Treponema denticola was present at significantly higher absolute counts at the healthy as well as periodontitis sites of the khat chewers (OR = 3.13 and 13, respectively). However, the khat chewers harbored significantly lower absolute counts of Porphyromonas gingivalis at the healthy sites (OR = 0.07). Furthermore, khat chewing was significantly associated with lower relative counts of Porphyromonas gingivalis, fusobacterium ssp., prevotella ssp. and Parvimonas micra-like species in subgingival plaque samples from both healthy and periodontitis sites (OR = 0.11-0.33). Only Treponema denticola was found in higher relative counts at the healthy sites of the khat chewers (OR = 2.98).

Conclusions

Overall, there was a lower burden of pathogens in the khat chewers. Findings from the current study are suggestive of a potential prebiotic effect for khat on periodontal microbiota.  相似文献
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