Association between night sleep latency and hypertension: A cross-sectional study

Sleep disorders have been shown to increase the risk of hypertension, while the relationship between night sleep latency and hypertension is less well-known. We aimed to investigate the association between night sleep latency and hypertension, as well as related sleep factors by gender in the Chinese population. We conducted a cross-sectional study of the relationship between night sleep latency and hypertension. The sample size included 619 consecutive hospitalized patients (M/F: 302/317, 64.01 ± 12.27 years). T test, Chi-square test, and ANOVA were performed to analyze baseline data and intergroup comparisons. Spearman correlation analysis was performed to find the interrelationships. Multivariate logistic regression analysis was performed to adjust for covariables. The findings showed hypertension patients had longer night sleep latency (P < .001). After adjusting for confounding factors, night sleep latency was positively correlated with hypertension in both men and women (odds ratio: 1.065, 95% confidence interval: 1.044–1.087). Spearman correlation analysis suggested that night sleep latency was positively correlated with systolic blood pressure (r = 0.186, P < .001), diastolic blood pressure (r = 0.136, P < .001), sleep initiation time (r = 0.091, P = .023), and global Pittsburg Sleep Quality Index score (r = 0.371, P < .001), was negatively correlated with sleep duration (r = −0.186, P < .001), sleep time on weekdays (r = −0.183, P < .001), and sleep time on weekends (r = −0.179, P < .001). Longer night sleep latency was associated with an increased risk of hypertension in men and women, which might involve the pathological progression of hypertension along with other sleep factors.     

老年人睡眠障碍与认知损害的关系及相关影响因素分析

目的 探讨老年人认知损害与睡眠障碍的关系并且分析引起认知损害的影响因素,为改善老年人睡眠质量及认知功能提供参考.方法 2016年1月至2017年12月,石家庄市第八医院精二科门诊及病房,通过方便取样对152例伴有失眠的老年人进行问卷调查,并另选取150例健康志愿者(睡眠正常组)进行比较.采用匹茨堡睡眠质量指数量(PSQ...     

福州地区综合性大学本科生睡眠状况调查及其干预的研究

目的了解福州地区综合性大学本科生睡眠状况,为心理健康教育提供依据。方法用匹兹堡睡眠质量指数问卷（PSQI）,对328名福州市综合性大学本科生进行调查。结果①大学生睡眠质量总分为5.51±2.28,睡眠状况不佳的有22.9%;②性别对主观睡眠质量、睡眠障碍和总体睡眠质量有影响;③不同年级大学生的睡眠情况存在显著差异;④专业因素对睡眠障碍有影响;⑤拥有电脑情况对睡眠障碍有影响。结论应重视大学生睡眠状况,有针对性地加强睡眠咨询和干预。     

上海市浦东新区社区轻中度慢性阻塞性肺病患者睡眠质量与生命质量的关联研究

目的 研究上海市浦东新区社区轻中度慢性阻塞性肺病(chronic obstructive pulmonary disease,COPD)患者睡眠质量与生命质量之间的关联.方法 本研究为横断面研究,通过随机整群抽样选取6个社区中符合条件的轻中度COPD患者,开展问卷调查,收集相关信息.采用中文版匹兹堡睡眠指数量表(PSQ...     

Sleep quality is negatively related to video gaming volume in adults

Most literature on the relationship between video gaming and sleep disturbances has looked at children and adolescents. There is little research on such a relationship in adult samples. The aim of the current study was to investigate the association of video game volume with sleep quality in adults via face‐to‐face interviews using standardized questionnaires. Adults (n = 844, 56.2% women), aged 18–94 years old, participated in the study. Sleep quality was measured using the Pittsburgh Sleep Quality Index, and gaming volume was assessed by asking the hours of gaming on a regular weekday (Mon–Thurs), Friday and weekend day (Sat–Sun). Adjusting for gender, age, educational level, exercise and perceived stress, results of hierarchical regression analyses indicated that video gaming volume was a significant predictor of sleep quality (β = 0.145), fatigue (β = 0.109), insomnia (β = 0.120), bedtime (β = 0.100) and rise time (β = 0.168). Each additional hour of video gaming per day delayed bedtime by 6.9 min (95% confidence interval 2.0–11.9 min) and rise time by 13.8 min (95% confidence interval 7.8–19.7 min). Attributable risk for having poor sleep quality (Pittsburgh Sleep Quality Index > 5) due to gaming >1 h day was 30%. When examining the components of the Pittsburgh Sleep Quality Index using multinomial regression analysis (odds ratios with 95% confidence intervals), gaming volume significantly predicted sleep latency, sleep efficiency and use of sleep medication. In general, findings support the conclusion that gaming volume is negatively related to the overall sleep quality of adults, which might be due to underlying mechanisms of screen exposure and arousal.     

百乐眠胶囊联合艾司唑仑治疗失眠症的疗效观察

目的探讨百乐眠胶囊联合艾司唑仑治疗失眠症的临床疗效。方法选取2016-2018年到云浮市人民医院接受治疗的210例失眠症患者,根据给药不同将所有患者分为3组,每组患者70例。百乐眠组口服百乐眠胶囊,4粒/次,2次/d;艾司唑仑组晚上入睡前30 min口服艾司唑仑片,1片/次,1次/d;联合组口服百乐眠胶囊联合艾司唑仑片,相关药物服用方法同以上两组。三组患者均连续治疗2周。观察三组的临床疗效,比较三组患者匹兹堡睡眠质量指数(PSQI)和不良反应发生情况。结果治疗后,百乐眠组、艾司唑仑组、联合组总有效率分别是74.28%、82.86%、97.14%,联合组总有效率显著高于百乐眠组、艾司唑仑组,差异有统计学意义(P<0.05)。治疗后,3组患者PSQI评分均有所降低(P<0.05);但治疗后,联合组患者PSQI各评分均显著低于百乐眠组、艾司唑仑组(P<0.05)。百乐眠组、艾司唑仑组、联合组不良反应发生率分别是8.57%、22.86%、10.00%,艾司唑仑组失眠症患者不良反应发生率明显高于百乐眠组、联合组(P<0.05)。结论百乐眠胶囊联合艾司唑仑治疗失眠症具有较好的临床疗效,可显著降低PSQI评分,改善患者睡眠质量,具有一定的临床推广应用价值。     

短程小组认知行为治疗失眠伴慢性非恶性颈背痛的效果

目的 探讨短程小组认知行为治疗失眠伴慢性非恶性颈背部疼痛患者的效果.方法 选择2013年6月～2013年12月于首都医科大学附属北京世纪坛医院神经与精神病科诊治的,符合国际睡眠障碍分类第二版失眠的诊断标准,并伴慢性非恶性颈背部疼痛的患者39例,随机分为短程小组认知行为治疗组(干预组,20例)和单纯睡眠卫生教育组(对照组,19例).患者于治疗前,治疗结束后1、5周填写匹兹堡睡眠质量指数(PSQI)、睡眠日志、医院焦虑抑郁量表(HADS)和疼痛视觉模拟评分,比较并分析两组的结果.结果 两组治疗期间各有1例中途脱落未能完成治疗.干预组治疗结束后1周入睡时间、睡眠总时间、睡眠质量、睡眠效率、焦虑得分均较对照组改善[(39±18)比(65±28)min、(429±47)比(413±70)min、(3.8±1.6)比(3.5±1.5)分、(73±13)％比(66±12)％、(7.0±3.5)比(8.1±3.7)分],差异均有统计学意义(P＜0.05);治疗结束后5周干预组入睡时间、睡眠总时间、睡眠质量、睡眠效率、焦虑得分分别较对照组相应指标改善[(35±12)比(62±27)min、(440±52)比(418±75)min、(3.9±1.8)比(3.5±1.6)分、(76±12)％比(66±12)％、(6.5±2.4)比(7.8±3.3)分],差异均有统计学意义(P＜0.05).结论 短程小组认知行为治疗对失眠伴慢性颈背痛患者的失眠和伴随焦虑症状有持续的效果.     

Acupuncture and related therapies for poststroke insomnia: A protocol for systematic review and network meta-analysis

Objective:To compare and evaluate the clinical effects on patients with poststroke insomnia of various acupuncture and acupuncture-related therapies.Methods:In order to analyze the direct and indirect evidence from related studies, we used network meta-analysis (NMA). In order to collect randomized controlled trials (RCTs) of acupuncture and related therapies in the treatment of poststroke insomnia, 3 English and 4 Chinese databases were searched. After 2 researchers independently screened the literature, extracted the information, and assessed the probability of bias in the included studies, the data was analyzed using Stata15.0 and WinBUGS1.4.3 software.Results:Based on the existing data, the pros and cons of different acupuncture-related therapies are compared extensively, the effectiveness of different acupuncture-related therapies is ranked compared to drugs with hypnotic effect in poststroke insomnia care, and the best methods or combinations of acupuncture intervention are summarized.Conclusion:This study will provide new evidence for the safety and effectiveness of acupuncture-related therapies in the treatment of poststroke insomnia, and may be helpful for clinicians, poststroke insomnia patients, and clinical guideline makers to choose the optimal combination of acupuncture for the treatment of poststroke insomnia.Registration Number:INPLASY202120028.     

Effectiveness and safety profiling of zolpidem and acupressure in CKD associated pruritus: An interventional study

Background:Chronic kidney disease (CKD)-associated pruritus (CKD-aP) contributes to poor quality of life, including reduced sleep quality and poor sleep quality is a source of patient stress and is linked to lower health-related quality of life. This study aimed to investigate the effectiveness of zolpidem 10 mg and acupressure therapy on foot acupoints to improve the sleep quality and overall quality of life among hemodialysis patients suffering from CKD-aP.Method:A multicenter, prospective, randomized, parallel-design, open label interventional study to estimate the effectiveness of zolpidem (10 mg) oral tablets versus acupressure on sleep quality and quality of life in patients with CKD-aP on hemodialysis. A total of 58 hemodialysis patients having sleep disturbance due to CKD-aP completed the entire 8-week follow-up. The patients were divided into a control (acupressure) group of 28 patients and an intervention (zolpidem) group of 30 patients.Results:A total of 58 patients having CKD-aP and sleep disturbance were recruited. In the control group there was a reduction in the PSQI score with a mean ± SD from 12.28 ± 3.59 to 9.25 ± 3.99, while in the intervention group the reduction in PSQI score with a mean ± SD was from 14.73 ± 4.14 to 10.03 ± 4.04 from baseline to endpoint. However, the EQ5D index score and EQ-visual analogue scale (VAS) at baseline for the control group with a mean ± SD was 0.49 ± 0.30 and 50.17 ± 8.65, respectively, while for the intervention group the values were 0.62 ± 0.26 and 47.17 ± 5.82, respectively. The mean EQ5D index score in the control group improved from 0.49 ± 0.30 to 0.53 ± 0.30, but in the intervention group there was no statistical improvement in mean EQ5D index score from 0.62 ± 0.26 to 0.62 ± 0.27 from baseline to week 8. The EQ 5D improved in both groups and the EQ-VAS score was 2.67 points higher at week 8 as compared to baseline in the control group, while in the intervention group the score was 3.33 points higher at week 8 as compared to baseline. Comparing with baseline, the PSQI scores were significantly reduced after week 4 and week 8 (P =  < .001). Furthermore, at the end of the study, the PSQI scores were significantly higher in the control as compared to the intervention group (P = .012).Conclusion:An improvement in sleep quality and quality of life among CKD-aP patients on hemodialysis has been observed in both the control and intervention groups. Zolpidem and acupressure safety profiling showed no severe adverse effect other that drowsiness, nausea and daytime sleeping already reported in literature of zolpidem.     

航空官兵睡眠障碍状况及相关因素分析

目的:调查航空官兵睡眠障碍状况及相关因素,为改善航空官兵的睡眠质量提供依据。方法:采用整群分层抽样方法,以匹兹堡睡眠质量指数(PSQI)、自尊量表(SES)、压力知觉量表(PSS)、健康调查量表(SF-36)、艾森克人格问卷(EPQ)评定航空官兵的睡眠状况及其影响因素。结果:1PSQI7者390人,占29.37%,7≥PSQI5者229人,占17.24%;2PSQI总分与PSS总分(r=0.41,P0.01)、SES总分(r=0.22,P0.01)、生理机能(PF)(r=-0.14,P0.01)、生理职能(RP)(r=-0.28,P0.01)、躯体疼痛(BP)(r=-0.52,P0.01)、社会功能(SF)(r=0.23,P0.01)、情感职能(RE)(r=-0.326,P0.01)、健康变化(HT)(r=0.17,P0.01)、精神质(P)(F=2.32,P0.01)、神经质(N)(F=12.73,P0.01)、掩饰因子(L)(F=4.15,P0.01)存在相关性;3神经质、躯体疼痛、情感职能、健康变化、压力知觉量表总分进入线性回归方程。结论:航空官兵整体上存在睡眠障碍,应值得重视;其严重程度及发病情况受官兵的年龄、性格特点、对压力的感受性、心理状态及身体健康水平等多方面的影响,其中知觉压力的认知过程起到了介导作用。