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西洋参治疗慢性疲劳综合征(气阴两虚型)27例 总被引:1,自引:0,他引:1
目的 观察西洋参饮片治疗慢性疲劳综合征的临床疗效.方法 对门诊及病房27例慢性综合征(气阴两虚型)患者采用西洋参饮片代茶饮的治疗方法,14d为1疗程,每1疗程后统计疗效.结果 西洋参饮片代茶饮治疗慢性疲劳综合征(气阴两虚型)总有效率达96.30%.结论 西洋参治疗慢性疲劳综合征(气阴两虚型)有良好的治疗效果. 相似文献
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FK506及神经干细胞对异体神经移植生长的作用 总被引:1,自引:0,他引:1
目的 探讨大鼠坐骨神经异体神经移植后联合应用FK506(他克莫司)及神经干细胞(NSCs)的可行性.方法 制造大鼠坐骨神经缺损模型,异体神经移植修复;根据分组不施加干预因素、吻合口注入NSCs、腹腔注射FK506,通过运动及感觉评分、电生理检测、组织学检查,以及免疫组织化学染色,观察神经再生差异.结果 同时应用FK506及NSCs组,感觉及运动评分(5.32±1.43),神经传导速度(20.52±1.45)m/s,GAP43染色(965.72±369.17)都明显优于其他组(P<0.05).结论 FK506结合NSCs对异体神经移植生长具有促进作用.Abstract: Objective This experiment study the effect of FK506 and neural stem cells on the regeneration in nerve allografts. Methods An established rat sciatic nerve model was used. Sciatic nerve ( 10 mm) deficits were created in the Lewis rats. Nerves allografts were harvested from BN rats to repair the deficits of the Lewis rats. Group A received no treatment. Group B received neural stem cells. Group D received FK506. Group C receive both neural stem cells and FK506. Nerve regeneration was evaluated by standardized pin-prick and toe-spread tests. Nerve samples and gastrocnemius muscles were harvested for examination. Muscle denervation atrophy was evaluated by gastrocnemius weights. GAP-43 and BrdU (Two-step immunohistochemistry detection reagent) were assayed by immunohistochemistry test. Results Improved functional outcomes were observed in group C when compared with other groups. Nerve conduction velocity were (20. 52 + 1.45) m/s. The score of sense and motion were higher ( 5.32 ± 1.43 ) than other groups. Improved histomorphology and electrophysiologiy were observed in group C when compared with other groups. The concentrations of GAP-43 (965.72 + 369. 17) were largest in group C, showing ststistically significant difference between groups (P < 0. 05). Conclusion The combination of neural stem cells and FK506 can improve nerve regeneration. It may provide an expanded source for those afflicted with extensive nerve defects. 相似文献
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