BackgroundThis systematic review aims to determine the epidemiological profile, etiology and risk factors, prevention, diagnosis, treatment, cost-effectiveness, survival, and quality of life related to cervical cancer in Morocco.MethodsThis study was conducted according to the recommendations of the "preferred reporting items for systematic reviews and meta-analysis." The PubMed, ScienceDirect, Springer, Web of Science data bases were used, as was Google Scholar for the grey literature. The review protocol was registered in the PROSPERO register (CRD42021235241).ResultsFifty studies were selected. The mean age was 49.31 ±6.3 years. HPV infection prevalence ranged from 13.30% to 76%, with a peak in HIV-positive women. Acceptability of the HPV vaccine was higher among parents (35% and 82%) than among adolescents (16.9% to 46.6%). Knowledge of the vaccine and its price are two key factors related to vaccine acceptability among parents. This systematic review highlights that the fact that few eligible women (not more than 11%) were participating in the cervical cancer screening program. Moroccan women's level of knowledge and awareness regarding cervical cancer screening was low, negatively impacting their use of such screening tools, as illustrated by the high percentage (mean 76.32% ± 17.21) of women who had never been screened for cervical cancer. Treatment was the most significant component of the global care budget (95.87%), with an annual cost of $13,027,609. Five-year overall survival ranged from 41.3% to 73.6%, with higher survival rates for patients diagnosed at an earlier stage (77.3–85% for stage I). Lastly, low quality of life was observed in women with tumors at an advanced stage who had received brachytherapy and lacked social support.ConclusionsSubjects that require further investigation include Moroccan women's knowledge, attitudes, and awareness, especially among those at high risk of developing cervical cancer, and its impact on their quality of life and survival. 相似文献
ObjectiveTo examine the relationship between absent social support and depression among older adults from elderly care social organizations in Anhui Province, China.MethodsA cross-sectional study using a multi-stage stratified random sampling method was conducted in six selected cities of Anhui Province, China. A linear regression model was employed to estimate the association between absent social support and depression.ResultsAll in all, 1167 older people were included. Social support and the three dimensions studied were all negatively correlated with depression. These findings suggest that older people from elderly care organizations, who reported higher social support, were less likely to develop depression. This association also existed after stratified analysis in different areas: household (urban/rural), age and gender.DiscussionA higher level of social support was correlated with lower chances of experiencing depression. These findings are consistent with the majority of previous literature having reported on social support among elderly populations. However, some of our findings differ from those of other studies.ConclusionsOur study suggests that improved social support could help to prevent depression among older adults. 相似文献
Based on a typical residential area, this paper studies the characteristics of pollutant concentration changes in two rainfall runoffs and the first flush effect of rainfall. In rainfall runoff, the concentrations of seven pollutants (CODMn, TN, DTN, NH3-N, TP, DTP, and PO43−) increased during the initial rainfall period and decreased in the later period. Rainfall causes the erosion of pollutants on the underlying surface so that water pollution begins when rainfall runoff occurs, and the pollution level drops over time. The seven pollutants all experience this first flush effect, of which, rainfall has the strongest scouring effect on NH3-N produced by domestic sewage. The significant excess of pollutants in rainfall runoff should be considered by management departments. In addition, the existence of the first flush effect makes it possible in theory to partially intercept rainfall runoff to control water pollution, thereby reducing the cost of pollution control.
A poly(2-(N-morpholine) ethane sulfonic acid)/reduced graphene oxide (RGO) modified glassy carbon electrode (GCE) was prepared using an electropolymerization method, and was characterized by scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS). The electrochemical behaviors and simultaneous detection of ascorbic acid (AA), dopamine (DA) and uric acid (UA) at this electrode were studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Tests showed that this electrode exhibited excellent electrocatalytic activity towards the oxidation of AA, DA and UA. The oxidation peak currents of AA, DA and UA were proportional with their concentrations in the ranges 1.0 μM–30 μM (30 μM–100 μM), 0.05 μM–100 μM and 0.1 μM–100 μM, with detection limits of 0.43 μM, 0.0062 μM and 0.056 μM, respectively. In addition, this electrode exhibited an excellent selectivity, reproducibility and stability, and has been successfully used to determine real samples with satisfactory results.A sensitive electrochemical sensor for simultaneously detecting dopamine, ascorbic acid and uric acid.相似文献