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1.
In vitro testing of the extracts of medicinal plants collected from Islamabad and the Murree region on insulin secretagogue activity was carried out. Dried ethanol extracts of all plants (ZH1-ZH19) were dissolved in ethanol and DMSO, and tested at various concentrations (between 1 and 40 microg/mL) for insulin release from INS-1 cells in the presence of 5.5 mM glucose. Glibenclamide was used as a control. Promising insulin secretagogue activity in various plant extracts at 1, 10, 20 and 40 microg/mL was found, while in some cases a decrease in insulin secretion was also observed. Artemisia roxburghiana, Salvia coccinia and Monstera deliciosa showed insulin secretagogue activity at 1 microg/mL (p < 0.05) while Abies pindrow, Centaurea iberica and Euphorbia helioscopia were active at 10 microg/mL (p < 0.05). Extracts of Bauhinia variegata and Bergenia himalacia showed effects at 20 microg/mL (p < 0.05), and Taraxacum officinale and Viburnum foetens at 40 microg/mL (p < 0.05). Insulin secretagogue activity could not be detected in the extracts of Adhatoda vasica, Cassia fistula, Chrysanthemum leucanthemum, Morus alba, Plectranthus rugosus, Peganum harmala and Olea ferruginea. The results suggest that medicinal plants of Islamabad and the Murree region of Pakistan may be potential natural resources for antidiabetic compounds.  相似文献
2.
This paper is based on the results of an ethnobotanical research project conducted in Margalla Hills National Park. The inhabitants of the park have always used medicinal herbs for various ailments and have for a long time been dependent on surrounding plant resources for their food, shelter, fodder, health care, and other cultural purposes. However, encroaching industrialisation and the accompanying changes in their life styles are responsible for the decrease of practice in the local use of herbs for medicine. It is, therefore, felt worthwhile to record the native uses of these herbs before the information is lost. About 100 informants were interviewed in this regard. In total 50 species of herbs belonging to 27 families were recorded as used medicinally by inhabitants of the park, among which ten species are being sold in the local market. Asparagus adescendens Roxb., and Viola canesence Wall. ex Roxb. are found vulnerable to harvesting.  相似文献
3.
4.

Objective

To investigate the antimicrobial activity of commercially available honey and raw honey samples in Khyber Pakhtunkhwa, Pakistan, against pathogenic bacterial strains.

Methods

Well diffusion assays were performed to screen pure and diluted honey samples for antibacterial activity against six Gram-negative and six Gram-positive bacterial strains. Zones of inhibition were measured and compared with 10 mg Gentamycin.

RESULTS

When honey samples were diluted to 20%-70%, the honey samples showed no activity to mild antibacterial activity. The highest antibacterial activity was recorded when 90% and pure undiluted honey samples were tested and compared with a control Gentamycin disc (10 mg).

Conclusion

Commercially processed honey and raw honey samples from north-west of Pakistan possess good antimicrobial potential.  相似文献
5.

Ethnopharmacological relevance

This study was aimed to explore the indigenous knowledge of medicinal plant species of Baluch tribes in Saravan region, Baluchistan province, Iran.

Material and methods

Rapid appraisal approach along with the semi-structured open ended questionnaire, interviews and personal observations were used to collect the indigenous medicinal information. Quantitative analysis including the informant consensus factor (ICF) and use value (UV) was performed to evaluate the valued medicinal plants.

Results and discussion

A total 64 medicinal plants belonging to 30 families were reported from the study area. Among families, Lamiaceae dominated over other families and leaves dominated with 31% over other plant parts used as herbal remedies. Rhazya stricta and Datura stamonium (0.35) attributed the higher UV, followed by Otostegia persica (0.33) and Teucrium polium (0.32). Results of the ICF showed that cold/flu/fever (0.71) and blood disorders (0.57) were the most common diseases of the study area.

Conclusion

The use value and informant consensus factor substantiated that the relative importance of plant species and sharing knowledge of herbal therapies between different tribal communities of this area is still rich.  相似文献
6.

Aim of study

The present study aimed to report the ethnomedicinal information from Kotli Sattian, district Rawalpindi for detailed medicinal uses and to inform the community about conservation of medicinal plant diversity and ethnomedicinal knowledge of plants.

Material and methods

Ethnomedicinal data were collected via Rapid Appraisal Approach (RAA) along with interview, group meetings with local people having awareness about medicinal knowledge of plants and individual meetings with local healers.

Results and discussions

This study reported eighty seven (87) indigenous medicinal plants, distributed among fifty five (55) families and seventy nine (79) genera. Among these, herbs contributed 43%, trees 28%, shrubs 21% and climbing plants 8%. About 34% of herbal preparations were made from whole plants followed by the leaves (27%), fruits (08%), bark (06%), seeds (05%), root (05%), rhizome (04%), stem, flower, gum, pod and tubers (02%) and milky latex (01%). Justicia adhatoda showed the maximum use value (0.91) while Cuscuta reflexa showed the least use value (0.11).

Conclusion

Elder people in the study area still rely on herbal remedies although the modern heath care facilities are present in the study area; thus, the indigenous plants remain important medicines in solving health problems.  相似文献
7.

Ethnopharmacological relevance

Two thirds of the world’s population relies on medicinal plants for centuries for several human pathologies. Present study aimed to identify, catalogue and document the large number of medicinal plants used in traditional medicine in Soan Valley, Salt Range, Pakistan.

Materials and methods

Informal interviews were conducted involving a total of 255 villagers (155 male and 65 female and 35 herbalists) to elicit the knowledge and use of medicinal plants.

Results

Local communities possessed knowledge of fifty eight (58) medicinal plant species belonging to thirty five (35) families to treat fifteen ailment categories. Whole plant and leaves were the most frequently used plant parts (24%) followed by seed (14%), root (12%), flower (7%), bulb (6%), fruit (4%), stem (3%), latex and rhizome (2%) and sap and gum (1%). Frequently used growth forms of medicinal plants were wild herbs (63%) followed by cultivated herbs (14%), wild trees (11%), wild shrubs (10%) and wild and cultivated herbs (2%). Preparations were administrated generally through oral and topical routes. Local people were familiar mostly with the species in order to deal common ailments particularly cough, cold, digestive problems, fever, headache, and skin infections. Complex ailments were treated by traditional healers. Justica adhatoda, Olea ferruginea, Amaranthus viridis and Mentha royleana were identified as plants with high use value (UV).

Conclusions

This study revealed that the area harbors high diversity of medicinal flora. Despite gradual socio-cultural transformation, local communities still hold ample knowledge of plants and their uses. The reliance on traditional medicines was associated with the lack of modern health care facilities, poverty and the traditional belief of their effectiveness. Medicinal plants play a significant role in management of various human diseases in the study area. A high degree of consensus among the informants was an indicative that plant use and knowledge were still strong, and preservation of this knowledge showed good foresight in the future. Awareness was thus needed to be raised among local people on sustainable utilization and management of plant resources.  相似文献
8.

Ethnopharmacological relevance

The current survey was aimed to identify the prime important medicinal plants in terms of medicines and further pharmacological screening of such plants. As far as, we know, no reported data from Deosai Plateau have been published and this is the first documented information of the study area.

Material and methods

Ethnomedicinal information of plants was collected through semi-structured interviews through a participatory rural appraisal (PRA) method.

Results and discussion

This study provided information of 50 medicinal plant species used to treat 29 different ailments. A total of 42 species (84%) were herbs while shrubs and subshrubs were represented by 8 species (16%). Leaves (37%) were the predominant plant parts followed by, roots (27%), aerial parts (13%), flowers (12%), fruit (7%), seeds (3%), and tuber (1%). Method of preparation fall into five categories including infusion (31%), paste (23%), decoction (20%), powder (18%), and juice (8%).

Conclusion

The study area is rich in medicinal plant diversity growing in wild. Our efforts in this regard are only a little contribution to the ethnobotanical study of this area focusing on medicinal plants while more clinical studies are required in future to prove such claims of local inhabitants.  相似文献
9.

Ethnopharmacological relevance

Malaria is among the most prevalent infectious diseases in the developing countries of world. Estimated number of annual malaria episodes in Pakistan is 1.5 million, but very little is known about medicinal plant species of Pakistan, which have great potential against malarial disease. Present study was aimed to document medicinal plant species used by the local inhabitants of Lesser Himalayas–Pakistan to treat malaria.

Materials and methods

Data were collected through interviews, questionnaires and contributor observation. A total of 55 informants aged between 25 and 80 years who were familiar with malarial disease participated in the survey.

Results

A total of 84 plant species belonging to 69 genera and 50 families were recorded to treat malaria. Asteraceae was found as most cited botanical family with (11.9%) representation, followed by Lamiaceae (5.9%), Solanaceae and Verbenaceae (4.7%) and Violaceae (3.5%) respectively. About 60% of the inhabitants prefer herbal treatment by local herbalists or self-treatment with locally available medicinal plant species. Of the plants identified during present investigation against malaria, Azadirachta indica, Swertia chirayita and Swertia ciliata exhibited uppermost frequency of encounter (36.3%) and corresponding PR value 5. About 67.2% of the botanical taxa are reported for the first time in the treatment of malaria. It was observed thatover harvesting is the foremost threat to medicinal plant species of the study area.

Conclusion

Present survey indicates that traditional knowledge about the use of plant species against various diseases and particularly to treat malaria is in decline. Similarly anthropogenic pressure, over exploitation and grazing of the botanical taxa are the major concerns regarding medicinal plant biodiversity loss. Frequently utilized plant species with significant malarial reduction should be authenticated by in vitro and in vivo standard tests  相似文献
10.

Ethnopharmacological relevance

Ethnomedicinal reports are important for the discovery of new crude drugs from reported medicinal plants with high use value. The current study aimed to document the medicinal flora as well as medicinal knowledge of indigenous plants of local communities from Layyah district, Punjab Province, Pakistan.

Material and methods

Rapid appraisal approach (RAA), semi-structured interviews, group meetings with herbalists, landowners and local people having awareness about the medicinal action of plants were employed to collect the data. Use values (UV) and frequency of citation (FC) were calculated to check the relative importance of plants.

Results and discussions

The current ethnomedicinal study reported 125 medicinal plant species diversified from 106 genus belonging to the 43 different families and Poaceae was the predominant family over others with 16 reported medicinal plants. Wild herbaceous plants were the predominant over other life forms while among plant parts, leaves contributed 32% followed by the stem (27%), fruit and flowers (15%). Allium sativum exhibited the highest use vale (UV) 0.92 while the lowest UV was exhibited by Lasiurus scindicus which was 0.15.

Conclusion

Local communities of district Layyah still have a strong faith on herbal medicines for basic healthcare needs. Indigenous plants having high UV and FC should be subjected to the detailed phytochemical investigations to explore new natural drugs.  相似文献
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