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排序方式: 共有142条查询结果,搜索用时 31 毫秒
1.
加热提取时间对柴胡皂甙A含量的影响   总被引:10,自引:0,他引:10       下载免费PDF全文
考察了柴胡合理的加热提取工艺,以柴胡皂甙A为检测指标,采用薄层扫描法,测定了不同加热提取时间柴胡皂甙A的含量,并比较了不同提取工艺对挥发油提取率的影响。结果表明,柴胡加热提取时间不宜超过6h。  相似文献
2.
In vitro anticancer activity of twelve Chinese medicinal herbs   总被引:9,自引:0,他引:9  
Aqueous extracts of 12 Chinese medicinal herbs, Anemarrhena asphodeloides, Artemisia argyi, Commiphora myrrha, Duchesnea indica, Gleditsia sinensis, Ligustrum lucidum, Rheum palmatum, Rubia cordifolia, Salvia chinensis, Scutellaria barbata, Uncaria rhychophylla and Vaccaria segetalis were evaluated for their antiproliferative activity on eight cancer cell lines as well as on normal human mammary epithelial cells. Five human and three murine cancer cell lines representing different tissues (breast, lung, pancreas and prostate) were used. All the crude aqueous extracts demonstrated growth inhibitory activity on some or all of the cancer cell lines, but only two showed activity against the normal mammary epithelial cells. Overall, the murine cell lines tended to be more sensitive to most of the extracts compared with the human cell lines. Among the human cell lines, cell type specificity was observed for two extracts. These results indicate the potential use of traditional Chinese medicinal herbs as antineoplastic agents and suggest that further studies evaluating their mechanism(s) of action and the isolation of active antitumor compounds are warranted.  相似文献
3.
女贞子研究进展   总被引:8,自引:1,他引:7       下载免费PDF全文
李勇  黄青  张洪岩  崔明华  张本 《中草药》1994,25(8):441-443
综述女贞子国内近40年来的研究进展。包括女贞子的真伪和优劣、化学成分及药理作用。  相似文献
4.
从古论今谈中医气象医学与防治温疫——“非典”   总被引:5,自引:0,他引:5       下载免费PDF全文
吴奇 《天津中医药》2003,20(3):60-64
“非典”的肆虐正在震撼着世界。但是从另一个角度上,却正在彻底改变着人们沿袭已久的不良生活习惯与整体卫生环境。同时,也在向医学界提出了严肃的课题:“类似温疫的流行,是否可预测及有效防治”。历史上有多次类似“非典”的温疫发生,而中医气象病理医学五运六气学,及温病学对于分析预测疾病的发生及有效的救治有独特的理论方法与治疗经验。本人就中国历史上几次温疫大流行,做了一下简单的回顾并特别强调指出乾隆癸未年1793年,发生在中国河北北京一带的温疫大流行,其中医学气象病理医学因素与今年2003年的医学气象病理学因素是完全一样的。而当时余师愚根据中医气象病理学五运六气学说分析创制清温败毒饮重用“生石膏”,救活了无数病人的宝贵经验,对于今天“非典”发展趋向的评估及救治,提供了非常宝贵的借鉴。  相似文献
5.
Tyrosinase inhibitory p-coumaric acid from ginseng leaves.   总被引:4,自引:0,他引:4  
By bioassay-guided fractionation using mushroom tyrosinase, p-coumaric acid was characterized as the principal tyrosinase inhibitor from the fresh leaves of Panax ginseng (Araliaceae). It inhibited the oxidation of L-tyrosine more strongly than that of L-3, 4-dihydroxyphenylalanine (L-DOPA) by this enzyme. On the basis of this finding, various related phenylpropanoid analogues were also tested in order to gain new insights into their structural criteria.  相似文献
6.
The effect of French maritime pine bark extract (PBE) on the gene expression profile of HaCaT human keratinocytes was studied using high density filter arrays. The expression profile of both control and PBE-treated cells was determined. Interestingly, PBE was shown to downregulate both calgranulin A and B genes which are known to be upregulated in psoriasis and various dermatoses. Thus, PBE could be considered in human dermatoses.  相似文献
7.
溶栓颗粒对缺血再灌注损伤大鼠IL-1β及MMP-9的影响   总被引:2,自引:0,他引:2  
目的:探讨溶栓颗粒对大鼠全脑缺血再灌注损伤的脑保护作用。方法:用四动脉夹闭(4VO)所致大鼠急性全脑缺血再灌注模型,放免法和免疫组化法分别检测血清IL-1β及脑组织MMP-9。结果:缺血再灌注损伤可造成大鼠血清IL-1β及脑组织MMP-9的高表达。中药组IL-1β及MMP-9的表达较少。结论:溶栓颗粒可以保护缺血再灌注大鼠受损伤脑组织,并可能通过减少血清IL-1β和脑组织MMP-9的途径实现。  相似文献
8.
Bioactive compounds from Rhodiola rosea (Crassulaceae)   总被引:2,自引:0,他引:2  
The methanol extract of the underground part of Rhodiola rosea was found to show inhibitory activity against Staphylococcus aureus. Bioactivity-guided fractionation of a 95% ethanol extract from the stems of R. rosea led to the isolation of five compounds: gossypetin-7-O-L-rhamnopyranoside (1), rhodioflavonoside (2), gallic acid (3), trans-p-hydroxycinnamic acid (4) and p-tyrosol (5). Their structures were elucidated by UV, IR, MS and NMR data, as well as by comparison with those of the literature. Compounds 1 and 2 were evaluated for their antibacterial and antiprostate cancer cell activities. Compounds 1 and 2 exhibited activity against Staphylococcus aureus with minimum inhibitory concentrations of 50 microg/mL and 100 microg/mL, respectively. Cytotoxicity studies of 1 and 2 also displayed activity against the prostate cancer cell line with IC(50) values of 50 microg/mL and 80 microg/mL, respectively.  相似文献
9.
A strain of Streptomyces nodosus (NPS007994) isolated from a marine sediment collected in Scripps Canyon, La Jolla, California, was found to produce lajollamycin (1), a nitro-tetraene spiro-beta-lactone-gamma-lactam antibiotic. The structure was established by complete analysis of spectroscopic data and comparison with known antibiotics oxazolomycin (2), 16-methyloxazolomycin (3), and triedimycin B (4). Lajollamycin (1) showed antimicrobial activity against both drug-sensitive and -resistant Gram-positive bacteria and inhibited the growth of B16-F10 tumor cells in vitro.  相似文献
10.
经穴一氧化氮生化生理学研究:进展与展望   总被引:2,自引:0,他引:2  
马胜兴 《针刺研究》2008,33(1):47-48
我们建立了人体皮肤表面穴位及经脉收集、测量一氧化氮代谢产物的方法。一氧化氮含量在人体心包经和膀胱经经穴增加,经抗菌处理后一氧化氮含量降低。据此,我们得出结论认为一氧化氮在皮肤表面经穴部位高水平是一种细菌参与的非生化酶化学合成过程,除此以外,还与L-精氨酸合成一氧化氮系统相关。一氧化氮介导皮肤交感神经产生去甲肾上腺素功能,因此经穴具有低电阻的特性。  相似文献
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