IntroductionThis study was designed to assess whether a dental caries management protocol combining a single application of 38% silver diamine fluoride (SDF) with comprehensive oral health education will successfully divert high-risk children from dental treatment under dental general anaesthesia (DGA), arrest active caries in primary teeth, and improve parent-reported child oral health–related quality of life (OHRQoL).MethodsChildren aged 2 to 10 years, who attended two public dental agencies in Victoria, Australia, and were unable to tolerate restorative treatments in the clinic setting, elected to participate in either a 38% SDF intervention protocol or, alternatively, referral for DGA. Follow-up examinations were completed at 6 months to assess caries progression, decayed missing filled tooth index, PUFA index (pulpal involvement, ulceration, fistula, abscess), DGA referral rates, and OHRQoL (Early Childhood Oral Health Impact Scale [ECOHIS]).ResultsOf the total sample, 89.5% of children (n = 102) [mean (SD) age, 4.1 (1.0) years] with 401 active carious lesions elected to participate in the 38% SDF protocol; 10.5% (n = 12) of parents opted for referral for treatment under DGA. The proportion of active caries subsequently arrested at follow-up (number of arrested lesions/number of lesions treated) was 0.78 (95% CI, 0.69 to 0.87). There was an 88% reduction in referrals for DGA in eligible children over the 6-month period. The 38% SDF intervention group showed a significant improvement in ECOHIS scores at follow-up (P < .001).DiscussionAdoption of the 38% SDF intervention protocol resulted in a significant reduction in the rate of preventable dental hospitalisations. Most parents opted against referral for DGA. Parent-reported OHRQoL for children improved significantly. 相似文献
Quality of Life Research - The COVID-19 pandemic might add to the stressors experienced by people living with rheumatic diseases. This study aimed to examine rheumatic patients’ functional... 相似文献
PurposeManagement of head and neck cancers (HNC) in older adults is a common but challenging clinical scenario. We assess the impact of Stereotactic Body Radiation Therapy (SBRT) on survival utilizing the Geriatric-8 (G8) questionnaire.Materials and methods171 HNC patients, deemed medically unfit for definitive treatment, were treated with SBRT ± systemic therapy. G8 questionnaires were collected at baseline, at 4–6 weeks, and at 2–3 months post-treatment. Patients were stratified according to their baseline G8 score: <11 as ‘vulnerable’, 11–14 as ‘intermediate’, and >14 as ‘fit’. Overall survival (OS) was assessed through univariate Kaplan Meier analysis. Repeated measures ANOVA was used to determine if baseline characteristics affected G8 score changes.ResultsMedian follow-up was seventeen months. 60% of patients presented with recurrent HNC, 30% with untreated HNC primaries, and 10% with metastatic non-HNC primaries. Median age was 75 years. Median Charlson Comorbidity Index score was 2. 51% of patients were ‘vulnerable’, 37% were ‘intermediate’, and 12% were ‘fit' at baseline, with median survival of 13.2, 24.3, and 41.0 months, respectively (p = .004). Patients who saw a decrease in their follow-up G8 score (n = 69) had significantly lower survival than patients who had stable or increased follow-up G8 scores (n = 102), with median survival of 8.6 vs 36.0 months (p < .001).ConclusionThe G8 questionnaire may be a useful tool in upfront treatment decision-making to predict prognosis and prevent older patients from receiving inappropriate anti-cancer treatment. Decline in follow-up G8 scores may also predict worse survival and aid in goals of care following treatment. 相似文献
The current study investigates the relationships among marital quality, self-compassion with psychological distress in women with primary infertility. It was hypothesized that marital quality and self-compassion are likely to predict psychological distress in women with primary infertility. It was further hypothesized that self-compassion is likely to mediate the relationship between marital quality and psychological distress in women with primary infertility. The sample was comprised of 115 women with primary infertility with an age range of 20–35 years (M?=?29.08, SD?=?3.908). The Relationship Assessment Scale (Hendrick in J Marriage Fam, 1988. https://doi.org/10.2307/352430), Self-compassion Scale (Neff in Self Identity 2(3):223–250, 2003. https://doi.org/10.1080/15298860309027), and Depression, Anxiety, Stress Scale (Lovibond and Lovibond in Manual for the depression anxiety stress scales, 2nd edn. Psychology Foundation, 1995) were used to measure the study variables. SPSS was used to analyze the data. Pearson Product Moment Correlation showed that marital quality was positively related to self-compassion and negatively associated with psychological distress (depression, anxiety, and stress). Furthermore, self-compassion was negatively associated with psychological distress (depression, anxiety, and stress). Mediation analysis with the help of Process Macro revealed that marital quality was significantly predicting depression and stress but not anxiety among women with primary infertility, whereas self-compassion was significantly predicting depression, anxiety, and stress among women with primary infertility. Self-compassion was significantly mediating the relationship between marital quality and psychological distress (depression and stress) in women with primary infertility. The study showed that self-compassion could be an important variable for the management of infertility-related issues.
