全文获取类型
收费全文 | 21404篇 |
免费 | 1117篇 |
国内免费 | 775篇 |
专业分类
耳鼻咽喉 | 679篇 |
儿科学 | 885篇 |
妇产科学 | 156篇 |
基础医学 | 1093篇 |
口腔科学 | 160篇 |
临床医学 | 2093篇 |
内科学 | 3731篇 |
皮肤病学 | 66篇 |
神经病学 | 130篇 |
特种医学 | 1360篇 |
外国民族医学 | 3篇 |
外科学 | 6346篇 |
综合类 | 3167篇 |
现状与发展 | 1篇 |
预防医学 | 469篇 |
眼科学 | 581篇 |
药学 | 1084篇 |
6篇 | |
中国医学 | 578篇 |
肿瘤学 | 708篇 |
出版年
2024年 | 13篇 |
2023年 | 258篇 |
2022年 | 389篇 |
2021年 | 602篇 |
2020年 | 625篇 |
2019年 | 564篇 |
2018年 | 600篇 |
2017年 | 586篇 |
2016年 | 686篇 |
2015年 | 653篇 |
2014年 | 1336篇 |
2013年 | 1266篇 |
2012年 | 1138篇 |
2011年 | 1353篇 |
2010年 | 1183篇 |
2009年 | 1207篇 |
2008年 | 1199篇 |
2007年 | 1252篇 |
2006年 | 1113篇 |
2005年 | 1017篇 |
2004年 | 840篇 |
2003年 | 684篇 |
2002年 | 593篇 |
2001年 | 542篇 |
2000年 | 447篇 |
1999年 | 365篇 |
1998年 | 308篇 |
1997年 | 305篇 |
1996年 | 233篇 |
1995年 | 253篇 |
1994年 | 209篇 |
1993年 | 175篇 |
1992年 | 146篇 |
1991年 | 127篇 |
1990年 | 130篇 |
1989年 | 105篇 |
1988年 | 113篇 |
1987年 | 77篇 |
1986年 | 78篇 |
1985年 | 82篇 |
1984年 | 90篇 |
1983年 | 54篇 |
1982年 | 64篇 |
1981年 | 47篇 |
1980年 | 50篇 |
1979年 | 43篇 |
1978年 | 30篇 |
1977年 | 24篇 |
1976年 | 21篇 |
1973年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
《European journal of surgical oncology》2022,48(3):482-491
ObjectiveTo systematically evaluate the clinicopathological and prognostic value of extra-hepatic bile duct resection (EHBDR) in the surgical management of patients with gallbladder carcinoma (GBC), especially in non-jaundiced patients.MethodsPubMed, EMBASE and the Cochrane Library were searched up to March 1st 2021 for comparative studies between bile duct resected and non-resected groups. RevMan5.3 and Stata 13.0 software were used for the statistical analyses.ResultsEHBDR did not correlate with a better overall survival (OS) (P = 0.17) or disease-free survival (P = 0.27). No survival benefit was also observed in patients with T2N1 (P = 0.4), T3N0 (P = 0.14) disease and node-positive patients (P = 0.75), rather, EHBDR was even harmful for patients with T2N0 (P = 0.01) and node-negative disease (P = 0.02). Significantly higher incidences of recurrent disease (P = 0.0007), postoperative complications (P < 0.00001) and positive margins (P = 0.02) were detected in the bile duct-resected group. The duration of postoperative hospital stay between the two groups was comparable (P = 0.58). Selection bias was also detected in our analysis that a significantly higher proportion of advanced lesions with T3-4 or III-IV disease was observed in the bile duct-resected group (P < 0.00001). EHBDR only contributed to a greater lymph yield (P = 0.01).ConclusionEHBDR has no survival advantage for patients with GBC, especially for those with non-jaundiced disease. Considering the unfairness of comparing OS between jaundiced patients receiving EHBDR with non-jaundiced patients without EHBDR, we could only conclude that routine EHBDR in non-jaundiced patients is not recommended and future well-designed studies with more specific subgroup analyses are required for further validation. 相似文献
3.
4.
5.
6.
7.
8.
《Asian journal of surgery / Asian Surgical Association》2021,44(8):1037-1042
BackgroundStoma-related obstruction (SRO) is defined as small bowel obstruction occurring around the limbs of diverting ileostomy (DI). This study was aimed to investigate the incidence, risk factors, and management of SRO after laparoscopic colorectal surgery with DI creation.MethodsThis study included 155 patients who underwent laparoscopic colorectal surgery with DI creation for rectal cancer (n = 138), ulcerative colitis (UC) (n = 14), and familial adenomatous polyposis (FAP) (n = 3) between 2011 and 2019. Univariate and multivariate analyses were performed to identify the risk factors of SRO.ResultsThe incidence of SRO was 7.7% (n = 12), and it was significantly lower (P < 0.01) in patients with lower anterior resection or intersphincteric resection (4.3%) than in those with ileal-pouch anal anastomosis (IPAA) (35.2%). The multivariate analysis revealed that IPAA was independently associated with the development of SRO (P = 0.001; odds ratio, 9.4; 95% confidence interval, 2.5–35.4). Eleven of 12 patients (92%) with SRO required trans-stomal tube decompression, and 8 of those (67%) underwent early stoma closure.ConclusionIPAA was an independent risk factor of SRO in laparoscopic colorectal surgery with DI creation. Early stoma closure was needed in most cases of SRO. 相似文献
9.
10.