全文获取类型
收费全文 | 1030篇 |
免费 | 72篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 64篇 |
妇产科学 | 3篇 |
基础医学 | 101篇 |
口腔科学 | 107篇 |
临床医学 | 89篇 |
内科学 | 171篇 |
皮肤病学 | 1篇 |
神经病学 | 108篇 |
特种医学 | 35篇 |
外科学 | 116篇 |
综合类 | 117篇 |
预防医学 | 146篇 |
眼科学 | 4篇 |
药学 | 23篇 |
中国医学 | 21篇 |
肿瘤学 | 5篇 |
出版年
2024年 | 1篇 |
2023年 | 20篇 |
2022年 | 27篇 |
2021年 | 59篇 |
2020年 | 47篇 |
2019年 | 34篇 |
2018年 | 34篇 |
2017年 | 35篇 |
2016年 | 31篇 |
2015年 | 40篇 |
2014年 | 53篇 |
2013年 | 59篇 |
2012年 | 72篇 |
2011年 | 55篇 |
2010年 | 47篇 |
2009年 | 36篇 |
2008年 | 54篇 |
2007年 | 43篇 |
2006年 | 29篇 |
2005年 | 27篇 |
2004年 | 13篇 |
2003年 | 24篇 |
2002年 | 29篇 |
2001年 | 20篇 |
2000年 | 19篇 |
1999年 | 16篇 |
1998年 | 10篇 |
1997年 | 9篇 |
1996年 | 7篇 |
1995年 | 15篇 |
1994年 | 14篇 |
1993年 | 16篇 |
1992年 | 12篇 |
1991年 | 16篇 |
1990年 | 11篇 |
1989年 | 9篇 |
1988年 | 4篇 |
1987年 | 10篇 |
1986年 | 17篇 |
1985年 | 13篇 |
1984年 | 4篇 |
1983年 | 9篇 |
1982年 | 5篇 |
1981年 | 5篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1978年 | 1篇 |
排序方式: 共有1114条查询结果,搜索用时 15 毫秒
1.
2.
《The Journal of thoracic and cardiovascular surgery》2023,165(2):449-459.e4
ObjectiveThe objective of this study was to investigate the association between morphological variation and postsurgical pulmonary vein (PV) stenosis (PPVS) in patients with cardiac total anomalous pulmonary venous connection (TAPVC).MethodsThis single-center, retrospective study included 168 pediatric patients who underwent surgical repair of cardiac TAPVC from 2013 to 2019 (connection to the coronary sinus [CS], n = 136; connection directly to the right atrium [RA], n = 32). Three-dimensional computed tomography modeling and geometric analysis were performed to investigate the morphological features; their relevance to the PPVS was examined.ResultsThe connection type had no association with PPVS (CS type: 18% vs right atrial type: 19%; P = .89) but there was a higher incidence of PPVS in patients with a single PV orifice than > 1 orifice (P < .001). Confluence-to-total PV area ratio (hazard ratio, 4.78, 95% CI, 1.86-12.32; P = .001) and length of drainage route (hazard ratio, 1.22; 95% CI, 1.14-1.31; P < .001) had a 4- and 1-fold increase in the risk for PPVS in the CS type after adjustment for age and preoperative pulmonary venous obstruction. In the right atrial type, those with anomalous PV return to the RA roof were more likely to develop PPVS than to the posterior wall of the RA (P < .001).ConclusionsThe number of inter-junction PV orifice correlated with PPVS development in cardiac TAPVC. The confluence-to-total PV ratio, length of drainage route, and anomalous PV return to the RA roof are important predictors for PPVS. Morphological subcategorization in this clinical setting can potentially assist in surgical decision-making. 相似文献
3.
Wendy Moyle Cindy Jones Toni Dwan Tamara Ownsworth Billy Sung 《Aging & mental health》2019,23(12):1643-1650
AbstractObjectives: To explore the acceptability of telepresence robots in dementia care from the perspectives of people with dementia, family carers, and health professionals/trainees, and investigate the utility of a social presence assessment tool, the Modified-Temple Presence Inventory (Modified-TPI), for people with dementia.Method: A mixed-methods pilot study conducted in a social robotics laboratory. Three participant groups (n?=?22) – dyads of people with dementia and their carers (n?=?5 respectively), and health professionals/trainees (n?=?12) – participated in individual one-off intervention sessions with the telepresence robot, Giraff, with follow-up interviews. Sessions covered how to use Giraff, followed by interactive practice in making a video-call involving conversation and manoeuvring of Giraff. Participants with dementia experienced receiving a call made by their carer; healthcare professionals/trainees experienced making and receiving a call. Outcomes of interest were sense of presence [Modified-TPI], affective response (International Positive and Negative Affect Schedule [I-PANAS-S]; Observable Displays of Affect Scale [ODAS]), and attitudes and reactions to Giraff (semi-structured interviews).Results: Participants reported a sense of authenticity and social connection through the experience. They indicated positive social presence through Giraff, and significantly higher positive (mean score 18.77; ±4.00) than negative affect (mean score 8.05; ±1.76) on the I-PANAS-SF, and on the facial display subscale of the ODAS (positive – mean score 15.50; ±3.51 versus negative – mean score 4.00; ±0.00).Conclusion: Telepresence has potential use in situations where people with dementia require social connection. Studies with larger sample sizes, varied characteristics, and cost-effectiveness analysis are needed to inform the application of telepresence in healthcare practice. 相似文献
4.
5.
Somayeh Maleki Balajoo Davud Asemani Ali Khadem Hamid Soltanian‐Zadeh 《Human brain mapping》2020,41(15):4264-4287
To estimate dynamic functional connectivity (dFC), the conventional method of sliding window correlation (SWC) suffers from poor performance of dynamic connection detection. This stems from the equal weighting of observations, suboptimal time scale, nonsparse output, and the fact that it is bivariate. To overcome these limitations, we exploited the kernel‐reweighted logistic regression (KELLER) algorithm, a method that is common in genetic studies, to estimate dFC in resting state functional magnetic resonance imaging (rs‐fMRI) data. KELLER can estimate dFC through estimating both spatial and temporal patterns of functional connectivity between brain regions. This paper compares the performance of the proposed KELLER method with current methods (SWC and tapered‐SWC (T‐SWC) with different window lengths) based on both simulated and real rs‐fMRI data. Estimated dFC networks were assessed for detecting dynamically connected brain region pairs with hypothesis testing. Simulation results revealed that KELLER can detect dynamic connections with a statistical power of 87.35% compared with 70.17% and 58.54% associated with T‐SWC (p‐value = .001) and SWC (p‐value <.001), respectively. Results of these different methods applied on real rs‐fMRI data were investigated for two aspects: calculating the similarity between identified mean dynamic pattern and identifying dynamic pattern in default mode network (DMN). In 68% of subjects, the results of T‐SWC with window length of 100 s, among different window lengths, demonstrated the highest similarity to those of KELLER. With regards to DMN, KELLER estimated previously reported dynamic connection pairs between dorsal and ventral DMN while SWC‐based method was unable to detect these dynamic connections. 相似文献
6.
7.
《Clinical neurophysiology》2020,131(8):1909-1916
ObjectiveFamily Nurture Intervention (FNI) facilitates mother/infant emotional connection, improves neurodevelopmental outcomes and increases electroencephalogram (EEG) power at term age. Here we explored whether delta brushes (DB), early EEG bursts that shape brain development, are altered by FNI and mediate later effects of FNI on EEG.MethodsWe assessed DB characteristics in EEG data from a randomized controlled trial comparing infants with standard care (SC, n = 31) versus SC + FNI (n = 33) at ~35 and ~40 weeks GA.ResultsCompared to SC infants, FNI infant DB amplitude increased more from ~35 to ~40 weeks, and FNI infants had longer duration DBs. DB parameters (rate, amplitude, brush frequency) at ~35 weeks were correlated with power at ~40 weeks, but only in SC infants. FNI effects on DB parameters do not mediate FNI effects on EEG power or coherence at term.ConclusionsDBs are related to subsequent brain activity and FNI alters DB parameters. However, FNI’s effects on electrocortical activity at term age are not dependent on its earlier effects on DBs.SignificanceWhile early DBs can have important effects on later brain activity in preterm infants, facilitating emotional connection with FNI may allow brain maturation to be less dependent on early bursts. 相似文献
8.
Salaam Semaan 《Emerging infectious diseases》2016,22(10):1863-1864
9.
10.
《Journal of hand therapy》2021,34(3):433-438
Study DesignThis is a cross-sectional study.IntroductionAn intertendinous connection between the flexor pollicis longus (FPL) and index flexor digitorum profundus (IFDP) tendons causes involuntary index flexion during active thumb flexion and has been named the Linburg-Comstock anomaly (LCA). It may become symptomatic or cause functional limitations. Literature has documented the prevalence to range from 13% to 70%. Cadaver studies have reported an anatomical connection in 5% to 25%.PurposeThis study aimed to examine the methodology and reliability of the LCA clinical diagnostic test and to explore the wide range of reported incidence and the discrepancy between cadaver and subject prevalence.MethodsTwo examiners observed for the presence of involuntary index flexion during 3 separate variations of thumb flexion in 67 subjects (134 limbs); results were considered positive if involuntary flexion occurred at either index interphalangeal joint. Intertester reliability was assessed using Cohen's kappa coefficient. The volar forearm and wrist of 53 cadavers (106 limbs) were dissected and assessed for an observable and mechanical tendinous connection between the FPL and IFDP tendons.ResultsPrevalence for subjects (5%-32%) was at the lower end of the range of previously reported values; results differed with altering thumb flexion motion. Observation for the presence of an intertendinous connection between the FPL and IFDP tendons in cadaver specimens (23%) fell within previously reported ranges. Intertester reliability coefficients ranged from no to weak agreement and varied according to specific thumb flexion motion performed during the test.ConclusionsThe identification of index finger flexion during thumb flexion varied both with thumb flexion motions and with whether flexion was assessed at the index proximal interphalangeal or distal interphalangeal joint. Intertester reliability was low for all variations of the LCA clinical test performed. The wide range in previously reported LCA incidence may be due to variability in testing procedure, and there is a need to establish a reliable and valid clinical test for this potentially symptomatic anatomic anomaly. 相似文献