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排序方式: 共有313条查询结果,搜索用时 15 毫秒
1.
目的:通过核酸检测新型冠状病毒,探讨PCR检测方法在新型冠状病毒和其他病原体感染的临床应用。方法:收集1例确诊患者送检的咽拭子样本,通过柱提法提取病毒RNA,使用商品化的扩增试剂和传统PCR技术进行检测。结果:A、B、C、D、E、F、G新冠检测试剂盒的结果均为阳性,PCR也能扩增出特异性条带,此外还检测出该患者有EB病毒和腺病毒病原体感染的情况。结论:7种扩增试剂盒检出阳性样本结果基本一致,均可用于实验室检测,该样本检测出新冠病毒的同时还检测出其他呼吸道相关病原体,为新冠肺炎的鉴别、诊断、治疗提供依据。 相似文献
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Xin Yao Lian‐Lian Bian Wei‐Wei Lu Jing‐Xin Li Qun‐Ying Mao Yi‐Ping Wang Fan Gao Xing Wu Qiang Ye Miao Xu Xiu‐Ling Li Feng‐Cai Zhu Zheng‐Lun Liang 《Journal of medical virology》2015,87(12):2009-2017
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目的探讨北京地区成人其他细菌性感染性腹泻的临床特点、流行病学、病原菌分布及耐药性,为疾病诊治及肠道传染病防控提供依据。方法回顾性收集2016年1月1日至2018年10月31日首都医科大学附属北京潞河医院感染性疾病科肠道门诊确诊的264例其他细菌性感染性腹泻患者的临床资料,对患者年龄、发病时间、临床特点、粪便标本细菌培养及药敏试验结果进行分析。结果本组患者中位年龄为42岁,男性占47.0%,临床症状以腹痛、腹泻、呕吐、发热为主,其中193例(73.1%)患者可追问到可疑不洁饮食史。264例患者粪便标本均分离出病原菌,共282株,其中以致病性大肠埃希菌最为常见(127株,45.0%),其次为副溶血弧菌(79株,28.0%)和沙门菌(48株,17.0%)。共有9例(3.41%)患者为混和菌感染,致病菌检出高峰为6~10月,集中在夏秋季。不同病原菌有不同的耐药谱,但其对亚胺培南敏感率均达100%;3种主要病原菌对抗生素药物均有多重耐药状况,其中致病性大肠埃希菌对氨苄西林、红霉素、头孢唑林、复方磺胺甲恶唑及四环素类明显耐药,但对头孢他啶、头孢西丁、氯霉素及头孢噻肟等较敏感;副溶血性弧菌对红霉素、萘啶酸、头孢唑林、阿奇霉素耐药,但对其他抗生素均较敏感;沙门菌对红霉素、萘啶酸、环丙沙星耐药,但对头孢西丁、氯霉素、复方磺胺甲恶唑、阿奇霉素较敏感。结论其他细菌性感染性腹泻好发于夏秋季,多与不洁饮食有关,病原菌以致病性大肠埃希菌、副溶血弧菌、沙门菌多见,临床医生应加强对其他细菌性感染性腹泻的认识,提高诊治率,并根据药敏试验结果合理选择抗生素治疗。 相似文献
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《Journal of the American Dental Association (1939)》2022,153(1):59-66
BackgroundThere is little published research on whether public and private dental benefits plans affect the types of oral health care procedures patients receive. This study compares the dental procedure mix by age group (children, working-age adults, older adults), dental benefits type (Medicaid and Children’s Health Insurance Program, private), and level of Medicaid dental benefits by state (emergency only, limited, extensive).MethodsThe authors extracted public dental benefits claims data from the 2018 Transformed Medicaid Statistical Information System. To compare procedure mix with beneficiaries who had private dental benefits, the authors used claims data from the 2018 IBM MarketScan dental database. The authors categorized dental procedures into specific service categories and calculated the share of procedures performed within each category. They analyzed procedure mix by age, plan type (fee-for-service, managed care), and adult Medicaid benefit level.ResultsAside from orthodontic services, the dental procedure mix among children with public and private benefits is similar. Among adults with public benefits, surgical interventions make up a higher share of dental procedures than routine preventive services.ConclusionsChildren with public benefits have a procedure mix comparable with those with private benefits. There are substantial differences in procedure mix between publicly and privately insured adults. Even in states that provide extensive dental benefits in Medicaid, those programs primarily finance invasive surgical treatment as opposed to preventive treatment.Practical ImplicationsThere is a need to assess best practices in publicly funded programs for children and translate those attributes to programs for adults for more equitable benefit design and care delivery across public and private insurers. 相似文献
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[摘要] 目的?分析陕西省宝鸡市2010—2019年手足口病流行特征及时空聚集性,为本市的手足口病防控提供理论依据。方法? 收集宝鸡市2010—2019年手足口病发病数据和病原学监测结果,建立数据库,分析手足口病流行特征及优势病原谱的变化,再应用ArcGIS 10.1系统对手足口病发病进行空间自相关及热点分析。结果?2010—2019年宝鸡市累计报告手足口病35 546例,平均发病率为94.62/10万,男性发病率高于女性(χ2=1031.484,P=0.000);各年龄组发病率不同(χ2趋势=61 405.833,P=0.000),其中1~2岁组年平均发病率最高(2572.65/10万)。宝鸡市手足口病病原谱的构成:2010年优势病原为Cox A16(65.14%),2011年、2012年和2014年优势病原为EV-A71(82.67%、48.97%和54.87%),2013年、2015—2018年均以其他肠道病毒为主(62.11%、49.34%、53.02%、42.29%、80.50%),2019年Cox A16和其他肠道病毒比例相当(55.42% vs. 43.07%),各年间优势病原分布不同(χ2=874.879,P=0.000)。全局自相关分析发现2014年、2017年、2018年、2019年具有空间聚集性,高值聚集区为本市南部地区及主城区。结论?陕西省宝鸡市手足口病发病存在时空聚集性,应加强重点地区疫情防控,制定针对性防控措施。 相似文献
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《Vaccine》2020,38(30):4717-4731
This is a Brighton Collaboration case definition of the term “Sensorineural Hearing Loss” to be utilized in the evaluation of adverse events following immunization. The case definition was developed by a group of experts convened by the Coalition for Epidemic Preparedness Innovations (CEPI) in the context of active development of vaccines for Lassa Fever and other emerging pathogens. The case definition format of the Brighton Collaboration was followed to develop a consensus definition and define levels of diagnostic certainty, after an exhaustive review of the literature and expert consultation. The document underwent peer review by the Brighton Collaboration Network. 相似文献
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Neural activities triggered by viewing other’s in pain have been previously reported to be modulated by various factors. How instructions of cooperation and competition can influence these activities has not been explored yet. In the current study, participants were instructed to play a game cooperatively or competitively with a partner. During the game, pictures showing an anonymous individual’s hand or foot in painful or non-painful situations were randomly presented in an oddball style. The event-related potentials (ERPs) when the participants passively observed these pictures under different instructions were compared. We found a significant interaction of Instruction × Picture on the P3 component, where only under competitive instruction did the painful pictures elicit significantly larger amplitudes than the non-painful pictures, but not under the cooperative instruction. This result indicates that the participants were more responsive to other’s pain in a competitive context than in a cooperative context. 相似文献
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Riffat Naz Asma Gul Urooj Javed Alina Urooj Sidra Amin Zareen Fatima 《Reviews in medical virology》2019,29(2)
Respiratory infections, especially those of the lower respiratory tract, remain a foremost cause of mortality and morbidity of children greater than 5 years in developing countries including Pakistan. Ignoring these acute‐level infections may lead to complications. Particularly in Pakistan, respiratory infections account for 20% to 30% of all deaths of children. Even though these infections are common, insufficiency of accessible data hinders development of a comprehensive summary of the problem. The purpose of this study was to determine the prevalence rate in various regions of Pakistan and also to recognize the existing viral strains responsible for viral respiratory infections through published data. Respiratory viruses are detected more frequently among rural dwellers in Pakistan. Lower tract infections are found to be more lethal. The associated pathogens comprise respiratory syncytial virus (RSV), human metapneumovirus (HMPV), coronavirus, enterovirus/rhinovirus, influenza virus, parainfluenza virus, adenovirus, and human bocavirus. RSV is more dominant and can be subtyped as RSV‐A and RSV‐B (BA‐9, BA‐10, and BA‐13). Influenza A (H1N1, H5N1, H3N2, and H1N1pdm09) and Influenza B are common among the Pakistani population. Generally, these strains are detected in a seasonal pattern with a high incidence during spring and winter time. The data presented include pneumonia, bronchiolitis, and influenza. This paper aims to emphasise the need for standard methods to record the incidence and etiology of associated pathogens in order to provide effective treatment against viral infections of the respiratory tract and to reduce death rates. 相似文献