首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   115篇
  免费   4篇
耳鼻咽喉   4篇
儿科学   5篇
妇产科学   1篇
基础医学   14篇
口腔科学   9篇
临床医学   18篇
内科学   13篇
皮肤病学   1篇
神经病学   3篇
特种医学   13篇
外科学   14篇
综合类   8篇
预防医学   8篇
眼科学   1篇
药学   1篇
中国医学   1篇
肿瘤学   5篇
  2023年   1篇
  2022年   1篇
  2021年   2篇
  2020年   6篇
  2019年   7篇
  2018年   2篇
  2017年   1篇
  2016年   3篇
  2015年   1篇
  2014年   7篇
  2013年   20篇
  2012年   8篇
  2011年   3篇
  2010年   3篇
  2009年   4篇
  2008年   3篇
  2007年   6篇
  2006年   5篇
  2005年   2篇
  2004年   2篇
  2003年   3篇
  2001年   3篇
  2000年   2篇
  1999年   3篇
  1997年   1篇
  1996年   2篇
  1995年   2篇
  1994年   3篇
  1991年   1篇
  1989年   2篇
  1987年   3篇
  1986年   1篇
  1985年   1篇
  1979年   1篇
  1976年   1篇
  1973年   3篇
排序方式: 共有119条查询结果,搜索用时 15 毫秒
1.
2.
《Foot and Ankle Surgery》2022,28(4):518-525
BackgroundRadiographic measurements are an essential tool to determine the appropriate surgical treatment and outcome for Hallux Valgus (HV). HV deformity is best evaluated by weight-bearing computed tomography (WBCT).The objective was (1) to assess the reliability of WBCT computer-assisted semi-automatic imaging measurements in HV, (2) to compare semi-automatic with manual measurements in the setting of an HV, and (3) to compare semi-automatic measurements between HV and control group.MethodsIn this retrospective IRB (ID# 201904825) approved study, we assessed patients with hallux valgus deformity. The sample size calculation was based on the hallux valgus angle (HVA). Thus to obtain the 0.8 power, including 26 feet with HV in this study, was necessary. Our control group consisted of 19 feet from 19 patients without HV. Raw multiplanar data was evaluated using software CubeVue®. In the axial plane, hallux valgus angle (HVA), intermetatarsal angle (IMA), and interphalangeal angle (IPA) were measured. The semiautomatic 3D measurements were performed using the Bonelogic®Software. Inter-rater reliabilities were performed using ICC. Agreement between methods was tested using the Bland-Altman plots. The difference between Patologic and Control cases using semi-automatic measurements was assessed with the Wilcoxon signed-rank test. Alpha risk was set to 5% (α = 0.05). P ≤ 0.05 were considered significant.ResultsReliabilities utilizing ICC were over 0.80 for WBCT manual measurements and WBCT semi-automatic readings. Inter and intraobserver agreement for Manual and Semi-automatic WBCT measurements demonstrated excellent reliability.ConclusionsSemi-automatic measurements are reproducible and comparable to measurements performed manually. The software differentiated pathological from non-pathological conditions when subjected to semi-automatic measurements. The development of advanced semi-automatic segmentation software with minimal user intervention is essential for the establishment of big data and can be integrated into clinical practice, facilitating decision-making.  相似文献   
3.
目的:探讨低出生体重儿经外周静脉置入中心静脉导管(PICC )置管最佳体外测量方法。方法2012年1月18日~2013年12月18日,对在我院进行PICC置管的低出生体重儿按置管时间随机分为观察组和对照组,观察组测量方法是经头静脉穿刺时,压脉带自穿刺点沿静脉走向,在右侧上肢外侧上行至锁骨中线,弯曲向下至右侧乳头与前正中线中点,经正中及贵要静脉穿刺时,压脉带自穿刺点沿静脉走向,在右侧上肢内侧上行至锁骨中线,弯曲向下至右侧乳头与前正中线的中点,再测量压脉带的长度,为导管预留置长度。对照组测量方法是自穿刺点至右胸锁关节长度,再加0.5 cm ,为导管预留置长度。比较两组患儿置管的准确率。结果观察组PICC置入上腔静脉中下段的准确率为77.8%,对照组PICC置入上腔静脉中下段的准确率为44.4%,两组比较 P<0.05,差异有显著意义。结论低出生体重儿PICC置管使用压脉带进行体外测量,可提高PICC置入上腔静脉中下段的准确率。  相似文献   
4.

Background

Recently, we described a model system which included corrections of high-resolution computed tomography (HRCT) bronchial measurements based on the adjusted subpixel method (ASM).

Objective

To verify the clinical application of ASM by comparing bronchial measurements obtained by means of the traditional eye-driven method, subpixel method alone and ASM in a group comprised of bronchial asthma patients and healthy individuals.

Methods

The study included 30 bronchial asthma patients and the control group comprised of 20 volunteers with no symptoms of asthma. The lowest internal and external diameters of the bronchial cross-sections (ID and ED) and their derivative parameters were determined in HRCT scans using: (1) traditional eye-driven method, (2) subpixel technique, and (3) ASM.

Results

In the case of the eye-driven method, lower ID values along with lower bronchial lumen area and its percentage ratio to total bronchial area were basic parameters that differed between asthma patients and healthy controls. In the case of the subpixel method and ASM, both groups were not significantly different in terms of ID. Significant differences were observed in values of ED and total bronchial area with both parameters being significantly higher in asthma patients. Compared to ASM, the eye-driven method overstated the values of ID and ED by about 30% and 10% respectively, while understating bronchial wall thickness by about 18%.

Conclusions

Results obtained in this study suggest that the traditional eye-driven method of HRCT-based measurement of bronchial tree components probably overstates the degree of bronchial patency in asthma patients.  相似文献   
5.
目的 通过对正常人海马体积的MRI测量,为与海马体积变化相关疾病的诊治及预后等提供参数值。 方法 选取健康志愿者240例,男性、女性各120例,按照年龄段分为5组,每组男女各24人,用1.5T MRI对所有的受试者行垂直海马长轴的斜冠状位1mm层厚扫描,经过识别、分割,进而计算海马的体积。 结果 (1)不同性别、侧别的海马体积两两比较,海马体积变化与性别、侧别无显著差异(P>0.05)。(2)男性40岁之前、之后的海马体积左、右侧别及组间比较均无显著差异(P>0.05),40岁之前、40岁之后的海马同侧别及组间比较有显著差异(P<0.05)。(3)女性60岁之前、之后的海马体积左、右侧别及组间比较均无显著差异(P>0.05),60岁之前与60岁之后的海马同侧别及组间比较有显著差异(P< 0.05)。 (4)男、女性左、右侧海马体积分别在相同组间比较,均无明显差异(P>0.05)。 结论 男性左右两侧海马体积在40岁之前变化不明显,40岁以后明显萎缩。女性左右侧海马体积在60之前变化不明显,60岁以后明显萎缩。  相似文献   
6.
Despite the well-established correlation between coronary heart disease (CHD) and hypertension, conventional anti-hypertensive therapy with diuretics and beta-adrenergic blockers has failed to provide protection against CHD. A possible explanation for this failure is the unfavourable effect such drugs have on lipid metabolism. To compare the lipid profiles of commonly used antihypertensive drugs, a survey was made of selected studies from the literature. Diuretics and selective and nonselective beta-blockers were found to have adverse effects on blood lipids. Beta-blockers with intrinsic sympathomimetic activity, labetalol, methyldopa, calcium channel blockers and ACE-inhibitors are lipid neutral, whereas alpha-adrenergic blockers seemed to have a favourable effect on lipid metabolism. Controlled clinical trials with drugs that have no adverse effects on lipid metabolism are needed to establish the long-term clinical importance of such agents.  相似文献   
7.
目的:通过测量华东地区不同年龄少年儿童颌面CT上舌骨的位置,研究少年儿童生长发育期间舌骨位置的变化及性别差异.方法:从上海交通大学医学院附属第九人民医院拍摄的(拍摄日期从2009年9月至2010年8月)颌面CT中筛选出281例华东地区少年儿童的CT图像,年龄6~18岁,男141例,女140例.将研究对象根据年龄分为4组,第1组为6~9岁(66例),第2组为10~12岁(62例),第3组为13~15岁(81例),第4组为16~18岁(72例).将CT原始图像数据通过三位图形软件进行三维重建,确定正中矢状面,在正中矢状面上测量舌骨点前后、垂直及相对颅底的位置参数.应用SPSS 16.0软件包中的t检验及线性相关分析对数据进行统计学分析.结果:舌骨前后向及相对颅底的位置在各年龄组均无性别差异.第3组和第4组舌骨垂直向位置有性别差异.男性舌骨前后、垂直向及相对颅底位置和女性舌骨垂直向位置与年龄呈正相关.上、下颌骨的位置与舌骨的位置相关.结论:在儿童期,舌骨位置未表现出性别差异;少年期,男性舌骨位置更低.随着年龄变化,男性舌骨位置表现出更大的变化.上、下颌骨位置影响舌骨的位置.  相似文献   
8.
Background and purposeThe association of leg length discrepancy (LLD) with a number of clinical disorders has made its determination a significant part of the physical examination. We believe that submalleolar causes of LLD may be under-acknowledged. The most common clinical method used to measure LLD is by tape from the anterior superior iliac spine (ASIS) to medial malleolus which disregards the potential for LLD arising from asymmetry in the foot distal to the tibiotalar joint.MethodsThe present pilot study involves a group of 5 volunteers (experimental group) and a group of 3 patients with flexible flat feet (clinical study). The differences in tibial tubercle height from the ground between full pronation and full supination were measured using the CODA MPX 30® system (Charnwood Dynamics Limited, Leicestershire, England). Correlations of the patterns within each group were produced.ResultsA significant relationship with leg lengths was found in the experimental group when they induced maximum pronation (R-squared = 0.62, p = 0.007) while an inverse relationship occurred with supination, although marginally significant (R-squared = 0.37, p = 0.064).ConclusionsWe have demonstrated that significant leg length discrepancy can occur in patients who do not have obvious deformity when non weight bearing. We recommend using the blocks method routinely. Appropriately measuring LLD is of vital importance to properly diagnosing and treating patients with unequal leg lengths or related symptoms.  相似文献   
9.
The objective of this study was to compare the short-term respiratory effects due to the inhalation of electronic and conventional tobacco cigarette-generated mainstream aerosols through the measurement of the exhaled nitric oxide (eNO). To this purpose, twenty-five smokers were asked to smoke a conventional cigarette and to vape an electronic cigarette (with and without nicotine), and an electronic cigarette without liquid (control session).  相似文献   
10.
INTRODUCTION: We attempt to see whether the ventricular measurements in routine CT scans performed prior to commencing donepezil differed in patients who duly responded well and those who did not, and to explore the potential application of the findings in clinical practice. METHOD: The study included all patients who were prescribed donepezil during a 2-year period in Warrington ( n =59). Two groups of patients were compared in respect of their baseline CT scan ventricular measurements: those who improved or remained stable cognitively on donepezil ( n =43) and those who declined while on donepezil (MMSE < 10) during the study period ( n =16). RESULTS: Significant differences in means between the two groups were found in relation to the bicaudate span and bicaudate ratio. Of ventricular measurements, only the bicaudate parameters were significantly correlated with the baseline Mini Mental State Examination (MMSE) score as well as the rate of decline in cognitive function during the study period ( P < 0.05). CONCLUSION: Baseline bicaudate diameter and ratio may be of some value if included in the initial assessment of patients on donepezil. These measurements, in conjunction with other cognitive and functional assessments, may prove helpful in deciding whether to commence treatment, and give a rough guide to the outcome. Future studies, with sufficient statistical power, are necessary to explore the use of ventricular parameters in predicting and monitoring patients' response to current and future pharmacological treatment in Alzheimer's disease.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号