全文获取类型
收费全文 | 4463篇 |
免费 | 386篇 |
国内免费 | 49篇 |
专业分类
耳鼻咽喉 | 28篇 |
儿科学 | 118篇 |
妇产科学 | 63篇 |
基础医学 | 273篇 |
口腔科学 | 87篇 |
临床医学 | 715篇 |
内科学 | 430篇 |
皮肤病学 | 17篇 |
神经病学 | 201篇 |
特种医学 | 92篇 |
外科学 | 345篇 |
综合类 | 717篇 |
预防医学 | 1089篇 |
眼科学 | 42篇 |
药学 | 392篇 |
16篇 | |
中国医学 | 94篇 |
肿瘤学 | 179篇 |
出版年
2024年 | 6篇 |
2023年 | 117篇 |
2022年 | 135篇 |
2021年 | 243篇 |
2020年 | 243篇 |
2019年 | 255篇 |
2018年 | 218篇 |
2017年 | 185篇 |
2016年 | 155篇 |
2015年 | 147篇 |
2014年 | 330篇 |
2013年 | 482篇 |
2012年 | 252篇 |
2011年 | 305篇 |
2010年 | 211篇 |
2009年 | 217篇 |
2008年 | 207篇 |
2007年 | 180篇 |
2006年 | 159篇 |
2005年 | 118篇 |
2004年 | 113篇 |
2003年 | 53篇 |
2002年 | 62篇 |
2001年 | 42篇 |
2000年 | 41篇 |
1999年 | 33篇 |
1998年 | 34篇 |
1997年 | 29篇 |
1996年 | 27篇 |
1995年 | 36篇 |
1994年 | 31篇 |
1993年 | 27篇 |
1992年 | 21篇 |
1991年 | 23篇 |
1990年 | 19篇 |
1989年 | 16篇 |
1988年 | 16篇 |
1987年 | 21篇 |
1986年 | 14篇 |
1985年 | 17篇 |
1984年 | 10篇 |
1983年 | 4篇 |
1982年 | 6篇 |
1981年 | 6篇 |
1980年 | 8篇 |
1979年 | 8篇 |
1977年 | 5篇 |
1975年 | 2篇 |
1974年 | 3篇 |
1973年 | 3篇 |
排序方式: 共有4898条查询结果,搜索用时 78 毫秒
1.
目的 探讨硕士研究生层次特殊体育教育专业教育体系。方法 运用世界卫生组织康复胜任力架构(RCF),形成特殊体育教育专业胜任力,并应用于特殊体育教育专业建设,探讨硕士研究生层次的特殊体育教育专业建设理论架构与方法体系。结果 基于RCF,构建了特殊体育教育教师的胜任力架构,涉及特殊体育教师的实践、专业精神、学习与发展、管理与领导力和研究5个领域,胜任力和活动的熟练程度须达到相应水平。特殊体育教育专业建设应在培养目标、教学方式、专业课程设置和教学评估4个方面突出RCF特色和围绕胜任力的培养进行建设。结论 运用RCF构建了基于胜任力的特殊体育教育硕士研究生层次的专业教育方案。该方案使用RCF说明特殊教师职业能力标准,并可以将此转化为基于胜任力的硕士研究生层次特殊体育教育专业建设的内容。运用RCF构建基于胜任力的特殊体育教育体系,该体系可以用于确定硕士研究生层次的特殊体育教育专业建设中的培养目标、教学形式、专业核心课程和教学评估内容与方法。 相似文献
2.
Henrik Linde Vilhelmas Bartusevicius Åke Norberg Fredrik Klevebro Jonathan Grip 《Acta anaesthesiologica Scandinavica》2023,67(3):277-283
Background
Esophagectomy is a major surgical intervention and a cornerstone in the treatment of esophageal cancer. There is clinical experience that blood lactate concentration often is elevated in the period following esophagectomy, but the incidence and clinical consequences are sparsely studied.Methods
We extracted data from all patients undergoing esophagectomy at Karolinska University Hospital 2016–2018, n = 153. Most were performed with minimally invasive technique, n = 130. Blood lactate values directly after surgery, highest value during the first night, and morning level on postoperative day one were recorded. Primary outcome was hospital length of stay and secondary outcome was a composite of postoperative infection, additional surgery, or intensive care during the hospital stay. Development of anastomotic leak was analyzed separately.Results
Postoperative hyperlactatemia was common as 93% of patients had peak lactate concentration >1.6 mmol/L and 27% >3.5 mmol/L in the first night following operation. Median hospital length of stay was 14 days. Blood lactate showed a weak correlation to hospital stay and intensive care the morning following surgery, but not at arrival to postoperative ward. There were no statistical differences between those with and without anastomotic leak at any of the time points. Elevated lactate in the first 12–16 h postoperatively was related to surgical factors (open technique, surgery time, and perioperative bleeding) but not to patient related factors (ASA-class, Charlson comorbidity index, sex, age) or cumulative fluid balance.Conclusion
In conclusion, elevated blood lactate in the immediate time following esophagectomy showed a weak association to intensive care and length of stay but not anastomotic leak. 相似文献3.
背景 全科医生数量和质量是人力资源管理的两个重要维度,其中,医生数量的新增、保持和流失,是全科人力动态规划、管理和评价的重要考量,也是全科住院医师规范化培训(简称全科住培)的绩效指标。探讨全科住培学员的就业状况及影响因素,可以为今后住培政策和激励机制的制定提供参考,但目前针对非订单定向全科住培学员的相关研究较为缺乏。 目的 了解河南省非订单定向全科住培学员的就业状况,分析学员结业后未从事全科医学相关工作的原因,从而为完善培训管理和人力资源激励机制提供参考。 方法 于2021年8月,采用分层随机整群抽样法,在河南省选取2014—2017年入培且已结业的非订单定向全科住培学员326例进行问卷调查。问卷由课题组自行设计,主要内容为学员的基本信息、全科住培情况、目前工作情况及结业后从事与未从事全科医学相关工作的原因。问卷通过"问卷星"平台发放,由学员自行填写。 结果 共发放问卷326份,回收有效问卷271份(83.1%)。结业后,从事全科医学相关工作者77例(28.4%),从事非全科医学相关工作者194例(71.6%)。多因素Logistic回归分析结果显示,年龄、文化程度、生源类型、全科住培基地所在区域是学员结业后是否从事全科医学相关工作的影响因素(P<0.05)。与结业后未从事全科医学相关工作的学员相比,结业后从事全科医学相关工作学员注册为全科医学专业的比例更高〔70.1%(54/77)比32.0%(62/194),P<0.05〕,在乡镇卫生院/社区卫生服务中心执业的比例更高〔49.4%(38/77)比6.2%(12/194),P<0.05)〕。194例未从事全科医学相关工作的学员中,从事内科学工作者78例(40.2%),从事急诊及危重症医学工作者33例(17.0%),从事外科学工作者17例(8.8%)。不选择从事全科医学相关工作的前3位原因分别为:单位安排〔34.5%(67/194)〕,所在单位没有全科医学科〔29.9%(58/194)〕,薪酬低〔26.8%(52/194)〕。 结论 非订单定向全科住培学员选择从事全科医学相关工作的比例较低,年龄、文化程度、生源类型及基地所在区域是影响因素。建议加大全科医学理念宣传,加快综合医院全科医学科建设,提高全科医生薪酬待遇,以此增加全科医生的职业吸引力。 相似文献
4.
Objective
The aim of the study was to estimate the effect of the state-based reinsurance programs through the section 1332 State Innovation Waivers on health insurance marketplace premiums and insurer participation.Data Source
2015 to 2022 Robert Wood Johnson Foundation Health Insurance Exchange Compare Datasets.Study Design
An event study difference-in-differences (DD) model separately for each year of implementation and a synthetic control method (SCM) are used to estimate year-by-year effects following program implementation.Data Collection/Extraction Methods
Not applicable.Principal Findings
Reinsurance programs were associated with a decline in premiums in the first year of implementation by 10%–13%, 5%–19%, and 11%–17% for bronze, silver, and gold plans (p < 0.05). There is a trend of sustained declines especially for states that implemented their programs in 2019 and 2020. The SCM analyses suggest some effect heterogeneity across states but also premium declines across most states. There is no evidence that reinsurance programs affected insurer participation.Conclusion
State-based reinsurance programs have the potential to improve the affordability of health insurance coverage. However, reinsurance programs do not appear to have had an effect on insurer participation, highlighting the need for policy makers to consider complementary strategies to encourage insurer participation. 相似文献5.
目的 探讨微信小程序合并时间管理器在眼科患儿出院宣教中的应用效果,为眼科护士出院宣教干预提供借鉴。方法 采用便利抽样法,选取98例眼科患儿监护人作为研究对象,将2021年2月-5月住院的49例患儿的监护人作为对照组,进行眼科常规出院宣教,将2021年6月-9月住院的49例患儿的监护人作为观察组,使用微信小程序合并时间管理器进行出院宣教干预。比较2组患儿监护人对疾病相关知识知晓情况、满意度及按时复诊人数。结果 干预1个月后,观察组疾病相关知识问卷得分、满意度得分及按时复诊率均高于对照组(t=-5.223,P=0.001;t=-5.419,P=0.001;χ2=6.874,P=0.009)。结论 使用微信小程序合并时间管理器在眼科病房进行出院宣教,能有效提高患儿监护人出院后疾病相关知识水平、按时就诊率及监护人满意度,提升护理服务质量。 相似文献
6.
Progress toward sustainable influenza vaccination in the Lao Peoples’ Democratic Republic, 2012–2018
《Vaccine》2019,37(23):3002-3005
Despite global recommendations for influenza vaccination of high-risk, target populations, few low and middle-income countries have national influenza vaccination programs. Between 2012 and 2017, Lao PDR planned and conducted a series of activities to develop its national influenza vaccine program as a part of its overall national immunization program. In this paper, we review the underlying strategic planning for this process, and outline the sequence of activities, research studies, partnerships, and policy decisions that were required to build Laos’ influenza vaccine program. The successful development and sustainability of the program in Laos offers lessons for other low and middle-income countries interested in initiating or expanding influenza immunization. 相似文献
7.
张媛媛 《中国继续医学教育》2020,(6):181-183
目的讨论人性化护理模式对手术室患者治疗效果。方法回顾分析我院2018年1月-2018年12月份手术室收治的160例患者,按照患者的个人意愿随机分为常规护理组和人性化护理组,每组各80例。分别采取常规护理和人性化护理,对比两组患者的治疗效果。结果根据数据统计结果显示,人性化护理组患者的护理满意度(73.75%)高于常规护理组(58.75%),P<0.05,具有统计学意义。结论由于手术室患者的病情较重,而且很容易对手术产生明显的恐惧情绪。而人性化护理模式能够照顾患者情绪,有效减少手术时间,增强患者的手术信息,确保整个手术顺利进行,也能够促进术后患者的康复效果。 相似文献
8.
Susanna Zanutto Chiara Maura Ciniselli Antonino Belfiore Mara Lecchi Enzo Masci Gabriele Delconte Massimo Primignani Giulia Tosetti Marco Dal Fante Linda Fazzini Aldo Airoldi Marcello Vangeli Francesca Turpini Giovanni Giuseppe Rubis Passoni Paolo Viaggi Monica Arena Roberta Ilaria Olimpia Motta Anna Maria Cantù Cristiano Crosta Giuseppe De Roberto Francesca Iannuzzi Andrea Cassinotti Valentina Dall'Olio Laura Tizzoni Gabriella Sozzi Emanuele Meroni Luigi Bisanti Marco Alessandro Pierotti Paolo Verderio Manuela Gariboldi 《International journal of cancer. Journal international du cancer》2020,146(4):1164-1173
Colorectal cancer (CRC) screening programs help diagnose cancer precursors and early cancers and help reduce CRC mortality. However, currently recommended tests, the fecal immunochemical test (FIT) and colonoscopy, have low uptake. There is therefore a pressing need for screening strategies that are minimally invasive and consequently more acceptable to patients, most likely blood based, to increase early CRC identification. MicroRNAs (miRNAs) released from cancer cells are detectable in plasma in a remarkably stable form, making them ideal cancer biomarkers. Using plasma samples from FIT-positive (FIT+) subjects in an Italian CRC screening program, we aimed to identify plasma circulating miRNAs that detect early CRC. miRNAs were initially investigated by quantitative real-time PCR in plasma from 60 FIT+ subjects undergoing colonoscopy at Fondazione IRCCS Istituto Nazionale dei Tumori, then tested on an internal validation cohort (IVC, 201 cases) and finally in a large multicenter prospective series (external validation cohort [EVC], 1121 cases). For each endoscopic lesion (low-grade adenoma [LgA], high-grade adenoma [HgA], cancer lesion [CL]), specific signatures were identified in the IVC and confirmed on the EVC. A two-miRNA-based signature for CL and six-miRNA signatures for LgA and HgA were selected. In a multivariate analysis including sex and age at blood collection, the areas under the receiver operating characteristic curve (95% confidence interval) of the signatures were 0.644 (0.607–0.682), 0.670 (0.626–0.714) and 0.682 (0.580–0.785) for LgA, HgA and CL, respectively. A miRNA-based test could be introduced into the FIT+ workflow of CRC screening programs so as to schedule colonoscopies only for subjects likely to benefit most. 相似文献
9.
Endoscopic submucosal dissection (ESD) is an established technique for the endoscopic therapy of dysplastic and early cancerous lesions throughout the gastrointestinal tract. The procedure requires both a sophisticated knowledge for lesion characterization and high‐level endoscopic skills. As a result, the learning curve is very steep and, in Japan, it takes years to gain proficiency under the traditional Master‐Apprentice teaching model. At present, as a result of multiple limitations, this training model is not applicable to the USA. Nevertheless, a unique, multipronged, stepwise approach has emerged as a viable pathway to train US endoscopists in ESD. Although this approach deserves refinement, it has already led to the expansion of ESD in the USA, has contributed to the widening of the indications for ESD, and has further developed ESD techniques. Multiple challenges remain, but they can be overcome by active collaboration between Japanese and US endoscopists and professional societies. The robust interest in ESD in the USA has drawn industry attention with a few innovations already coming to fruition and many more in development. 相似文献
10.