小剂量肝素及硫酸镁辅治婴幼儿毛细支气管炎45例报告

婴幼儿患毛细支气管炎时，机体明显缺氧、酸碱平衡失调、电解质紊乱，病情变化快，极易导致死亡。过去只重视控制感染，止咳化痰，忽视了严重感染缺氧造成高凝状态及易并发心衰，是死亡的重要原因。为此，我们在抗炎基础上加用小剂量肝素及硫酸镁治疗毛细支气管炎疗效满意，现报告如下。     

西安市部分腹泻患儿病原检出情况分析

对我院 1997年急住腹泻患儿 15 10例进行分析 ,现报道如下。对象及方法 :我院 1997年 1～ 12月住院和部分门诊急性腹泻患儿 15 10例 ,年龄 0～ 14岁 ,均符合 1998年《中国腹泻病诊断治疗方案》的诊断标准 ,所有患儿均在就诊当天用无菌棉拭子沾取大便 ,将大便接种于ＳＳ和麦康培养液中 ,37℃ ,2 4ｈ培养 ,可疑菌落进行细菌鉴定与药敏试验。结果 :(1)病原检出率及病原构成作者单位 :710 0 0 3西安市儿童医院急诊科比 :15 10例患儿能证实为细菌感染的2 0 9例 ,阳性率为 13.84% ,其中福氏痢疾杆菌 15 9株 (76 .0 8% ) ,致病性大肠杆菌 (ＥＰＥＣ…     

2台全自动生化分析仪测定丙氨酸氨基转移酶的比对分析

目的通过对日立-7080型和迈瑞BS-380型全自动生化分析仪方法比对,探讨不同仪器间丙氨酸氨基转移酶(ALT)检测结果的可比性。方法日立-7080全自动生化分析仪作参考仪器,迈瑞BS-380型全自动生化分析仪作为试验仪器,每天选取新鲜血清,分别在2台仪器上测定,并记录结果。用Microsoft ExceL 2003和软件SPSS13.0对2台仪器的结果采取回归和相关分析,求其相关系数(r)及回归方程Y=bX+a,以美国临床实验室修正法规(CLIA′88)规定的室间质量评价允许误差范围的1/2为标准,判断2台仪器测定结果的临床可接受性。结果 2台仪器ALT检测结果差异无显著性(r>0.975)。结论 2台仪器的ALT检测结果具有较好的可比性。     

改良UW灌注液治疗新生猪急性肾小管坏死的实验研究

目的 通过改良UW(University of Wisconsin solution)肾保存液在体肾动脉灌注,探讨改良UW肾保存液对新生猪急性肾小管坏死的治疗作用.方法 出生1周无特殊病原体幼猪10只,通过夹闭肾动脉制作急性肾小管坏死动物模型,将其分为模型组和改良UW灌注治疗组,每组5只,另设5只为假手术组.分别记录术后各组幼猪12 h、1 d、2 d、3 d、7 d的尿量并进行尿蛋白定量及静脉血中尿素氮(BUN)和肌酐(Cr)含量的检测,同时于术后12 h、24 h及7 d行肾脏病理学检查.结果 10只幼猪经肾脏病理和血生化检查证实建模成功,术后12 h模型组和灌注治疗组BUN和Cr含量明显高于假手术组,差异有统计学意义(P＜0.05),其含量在第2天达到峰值,第7天均显著降低,以灌注治疗组最为显著,并恢复至假手术组水平.尿蛋白定量模型组和灌注治疗组与假手术组比较各时间段均明显升高,差异有统计学意义(P＜0.05或P＜0.01),1 d后达到峰值,后缓慢下降,灌注治疗组下降尤为明显.尿量在模型组各时间段均较假手术组显著减少(P＜0.05或P＜0.01);而灌注治疗组只在12 h、1 d、2 d减少,差异有统计学意义(P＜0.05),在3 d、7d则无统计学意义.肾脏病理学检查提示:与模型组相比灌注治疗组的病理学改变较模型组明显减轻.结论 肾动脉灌注改良UW肾保存液可能具有缓解新生猪急性肾小管坏死程度的作用.

Abstract：

Objective To determine the effect of the modified UW (University of Wisconsin)solution in the treatment of acute renal tubular necrosis in newborn swine. Methods Ten one-week-old newborn swine were used to establish the animal model of acute renal tubular necrosis by clamping their renal arteries,and were divided into two groups: the model group( n = 5 ) and the treatment group ( n = 5 ) in which fructose diphosphate sodium UW solution was used. Sham surgery was performed on other five swine, which were used as the sham group. At 12 h,l d,2 d,3 d and 7 d after the operation,the urine volume,urine protein,blood urea nitrogen(BUN) and creatinine(Cr) were determined. At 12 h ,24 h and 7 d after the operation ,renal pathological examination was conducted. Results The renal pathological examination and the blood biochemistry tests showed that the animal model was successful. BUN and Cr in the model group and the treatment group were significantly higher than those in the sham group at 12 h after operation(P ＜0. 05) ,and they arrived at their peak values at 2 d after operation,showed remarkable decline at 7 d,especially in treatment group,and returned to the level of the sham group. The urine protein in the model group and treatment group were higher than those in the sham group at various times(P ＜0.05 or P ＜0.01) and it peaked at 1 d after operation,then declining gradually,especially in the treatment group. Compared with the sham group,there were a significant decrease in the urine volume at various times in the model group(P ＜0. 05 or P ＜0. 01 ) ,while in the treatment group,the decrease in the urine volume were significant only at 12 h, 1 d and 2 d( P ＜ 0. 05 ) ,and turned insignificant at 3 d and 7 d. The pathological examination showed that the pathological changes in the treatment group were significantly milder than those in the model group. Conclusion The modified UW solution is effective in reducing the acute renal tubular necrosis in newborn swine.     

对年轻护士管理的问答

问：年轻护士与年长的护士似乎对工作态度有很大差别,怎样对这些年轻人进行更有效的管理呢？答：当今年轻护士一般出生于６０～８０年代,他们更倾向自作主张,勇于承担责任。另外,在工作中,他们的观点与父辈差异极明显,都希望按照自己的意愿取得成功,并得到相应的报...     

改良UW灌注液治疗新生猪急性肾小管坏死的实验研究

Objective To determine the effect of the modified UW (University of Wisconsin)solution in the treatment of acute renal tubular necrosis in newborn swine. Methods Ten one-week-old newborn swine were used to establish the animal model of acute renal tubular necrosis by clamping their renal arteries,and were divided into two groups: the model group( n = 5 ) and the treatment group ( n = 5 ) in which fructose diphosphate sodium UW solution was used. Sham surgery was performed on other five swine, which were used as the sham group. At 12 h,l d,2 d,3 d and 7 d after the operation,the urine volume,urine protein,blood urea nitrogen(BUN) and creatinine(Cr) were determined. At 12 h ,24 h and 7 d after the operation ,renal pathological examination was conducted. Results The renal pathological examination and the blood biochemistry tests showed that the animal model was successful. BUN and Cr in the model group and the treatment group were significantly higher than those in the sham group at 12 h after operation(P ＜0. 05) ,and they arrived at their peak values at 2 d after operation,showed remarkable decline at 7 d,especially in treatment group,and returned to the level of the sham group. The urine protein in the model group and treatment group were higher than those in the sham group at various times(P ＜0.05 or P ＜0.01) and it peaked at 1 d after operation,then declining gradually,especially in the treatment group. Compared with the sham group,there were a significant decrease in the urine volume at various times in the model group(P ＜0. 05 or P ＜0. 01 ) ,while in the treatment group,the decrease in the urine volume were significant only at 12 h, 1 d and 2 d( P ＜ 0. 05 ) ,and turned insignificant at 3 d and 7 d. The pathological examination showed that the pathological changes in the treatment group were significantly milder than those in the model group. Conclusion The modified UW solution is effective in reducing the acute renal tubular necrosis in newborn swine.