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张晓丹  张颖 《中医临床研究》2010,2(6):115-116,118
目的:应用St.George’s呼吸疾病问卷,进行慢性咳喘患者冬病夏治方面的临床研究,探讨St.George’s呼吸疾病问卷评价慢性咳喘患者生活质量的价值。方法:将慢性咳喘患者(慢性支气管炎及支气管哮喘患者)随机分为冬病夏治组与对照组,两组均给与St.George’s呼吸疾病问卷调查,冬病夏治组予中药敷贴结合穴位注射,对照组常规西医规范治疗。结果:①冬病夏治组治疗前后一年问卷评分比较P〈0.01,即冬病夏治组治疗前后有显著性差异;②冬病夏治组与对照组治疗前后评分差值比较,采用半定量积分法P〈0.05,即冬病夏治组与对照组治疗前后有显著性差异;③冬病夏治组与对照组治疗前后有效率比较,冬病夏治组有效率70.4%,对照组有效率48.1%,经卡方检验后,P〉0.05,故尚不能认为两组患者有效率的差异有统计学意义。此组检验有待样本量增加后继续分析。结论:St.George’s呼吸疾病问卷在评价慢性咳喘患者生活质量方面有着积极的价值;冬病夏治能够有效改善恳性咳喘患者的临床症状,提高生活质量,冬病夏治体现了中医简、便、验、廉独特优势,具有良好的社会效益和推广前景。  相似文献   
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Meghan Russell 《Nutrients》2012,4(9):1213-1218
Vitamin D3 has been called the “sunshine” vitamin since the formation of vitamin D is mediated by exposure to sunlight. Vitamin D3 is linked to many health benefits, however serum levels of vitamin D3 have been decreasing over the last few decades and the lower levels of vitamin D3 may have consequences on normal physiology. We investigated the association between serum 25-hydroxyvitamin D (25(OH)D) levels and stratum corneum conductance as well as the effect of topical application of cholecalciferol (vitamin D3) on dry skin. Eighty three subjects were recruited and blood serum levels and skin conductance measurements were taken after a one week washout. A correlation was observed between vitamin D levels and skin moisture content, individuals with lower levels of vitamin D had lower average skin moisture. Subsequently, a 3-week split leg, randomized, vehicle controlled clinical study was conducted on a subset of 61 of the above individuals who were identified with non-sufficient vitamin D serum levels. Topical supplementation with cholecalciferol significantly increased measurements of skin moisturization and resulted in improvements in subjective clinical grading of dry skin. Taken together our finding suggest a relationship between serum vitamin D3 (25(OH)D) levels and hydration of the stratum corneum and further demonstrate the skin moisture benefit from topical application of vitamin D3.  相似文献   
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