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近视眼是影响我国儿童青少年眼健康的焦点问题。远视储备是眼球发生近视前的屈光状态, 是眼轴长度与角膜及晶状体等参数之间动态匹配的结果, 对于近视眼防控意义重大。我国一直缺乏儿童眼球发育参数的指导依据以及遗传因素影响的参考资料, 尤其针对上述参数在儿童眼球正视化过程中变化规律的总结。为了促进儿童青少年近视眼防控工作的标准化, 规范人群筛查和临床治疗, 使社会各界对近视眼的预防干预和评价有据可依, 中华预防医学会公共卫生眼科分会基于我国不同地区儿童青少年的屈光不正调查数据, 针对我国学龄儿童正视眼在不同年龄段眼球远视储备、眼轴长度和角膜曲率的参考区间及相关遗传因素达成共识性意见。  相似文献   
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BackgroundSurgical planning of posterior referencing total knee arthroplasty (TKA) using computed tomography (CT) might lead to over-rotation of the femoral component because CT could not detect cartilage thickness of the posterior femoral condyle. The purpose of this study was to examine the rotational alignment difference of the femoral component between magnetic resonance imaging (MRI) and CT.MethodsFor elderly varus osteoarthritic patients, 66 varus osteoarthritic knee patients that underwent primary TKA were selected. Twenty-seven young patients who underwent primary anterior cruciate ligament reconstruction were selected as control. After the transepicondylar axis (CEA), the surgical epicondylar axis (SEA) and the posterior femoral condylar line (PCL) were drawn on CT and on MRI at the same angles as CT. Then, the practical PCL was drawn on MRI considering the cartilage thickness (the cartilage PCL). The angle between the SEA and the cartilage PCL (the cartilage posterior condylar angle (PCA)) was measured as preoperative planning. To investigate the accuracy of preoperative MRI measurement, the cartilage thickness on posterior femoral condyles was directly measured during TKA.ResultsThe cartilage PCA for varus osteoarthritic patients averaged 1.3 ± 1.3°. The cartilage PCA was 1.8 ± 1.0° significantly smaller than the bone PCA (the PCA measured on CT). Meanwhile, the cartilage PCA was 0.2 ± 0.4° significantly larger than the bone PCA in young people. The preoperative angle measurement on MRI strongly correlated with the direct measurement of cartilage thickness during TKA.ConclusionThere was 1.8° of divergence between MRI and CT in varus osteoarthritic patients due to cartilage degeneration of the medial femoral condyle. Cartilage assessment using MRI was useful for femoral component rotational alignment.  相似文献   
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目的建立深圳市罗湖地区健康成年女性人群血清糖类抗原125(CA125)、癌胚抗原(CEA)水平和CA125/CEA的参考区间并进行验证。方法对2019年7月至2020年7月进行健康体检的成年女性人群的数据进行分析,通过偏度-峰度值检验数据正态分性,对非正态分布的数据使用BOX-COX转换;采用四分位间距法剔除离群值后计算P95获得参考值上限;通过分析2020年8月的健康体检成年女性数据对其建立的参考区间进行验证。结果20~<40岁女性CA125水平参考值上限为32.63 U/mL,40~<50岁女性CA125水平参考值上限为31.09 U/mL,50~90岁女性CA125水平参考值上限为20.69 U/mL。20~<30岁女性CEA水平参考值上限为2.58 ng/mL,30~<40岁女性CEA水平参考值上限为2.60 ng/mL,40~<50岁女性CEA水平参考值上限为3.11 ng/mL,50~<60岁女性CEA水平参考值上限为3.96 ng/mL,60~90岁女性CEA水平参考值上限为5.76 ng/mL。20~<40岁女性CA125/CEA参考值上限为43.77,40~<50岁女性CA125/CEA参考值上限为34.51,50~<60岁女性CA125/CEA参考值上限为18.70,60~90岁女性CA125/CEA参考值上限为13.72。经验证各年龄段女性CA125、CEA和CA125/CEA新建参考区间用于检测结果判读的符合率均在90%以上,验证均通过。结论间接法建立参考区间适用于临床实验室。CA125和CEA参考区间存在年龄差异,本研究可为临床不同年龄女性的妇科疾病诊断提供参考依据。  相似文献   
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《Cancer cell》2022,40(10):1223-1239.e6
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目的 了解护理硕士专业学位研究生人文执业能力现状及影响因素,为开展护理教育提供参考。方法 采用一般资料问卷、护士人文执业能力量表和护士职业价值观量表对300名护理硕士专业学位研究生进行调查。结果 护理硕士专业学位研究生的人文执业能力得分为(100.61±13.40)分;多元线性回归显示,婚姻状况、读研前临床护理工作年限、家人的关心程度和职业价值观是护理硕士专业学位研究生人文执业能力的主要影响因素(均P<0.05)。结论 护理硕士专业学位研究生人文执业能力有待加强,护理教育者应制订针对性培养方案,强化学生的人文护理意识、培训人文关怀技能、营造人文关怀氛围和注重职业价值观的引导,以提升护理硕士专业学位研究生人文执业能力水平。  相似文献   
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Previous studies have demonstrated that four latent variables, or reference abilities (RAs), can account for the majority of age‐related changes in cognition: these being episodic memory, fluid reasoning, speed of processing, and vocabulary. In the current study, we focused on RA‐selective functional connectivity patterns that vary with both age and behavior. We analyzed fMRI data from 287 community‐dwelling adults (20–80 years) on a battery of tests relating to the four RAs (three tests per RA = 12 tests). Functional connectivity values were calculated between a pre‐defined set of 264 ROIs (nodes). Across all participants, we (a) identified connections (edges) that correlated with an RA‐specific indicator variable and, indexing only these edges; (b) performed linear regression analysis per edge, regressing indicator correlations (Model 1) and connectivity values (Model 2) on Age, Behavioral Performance, and the Interaction term; and (c) took the conjunction of significant edges between models. Results revealed a different subset of edges for each RA whose connectivity strength and domain‐selectivity varied with age and behavior. Strikingly, the fluid reasoning RA was particularly vulnerable to the effects of age and displayed the most extensive connectivity and selectivity “footprint” for behavior. These findings indicate that different functional networks are recruited across RA, with fluid reasoning displaying a special status among them.  相似文献   
8.
目的 探讨磁性医院管理在基层托管二级民营医院的实践效果.方法 将磁性医院管理应用于托管二级民营医院:培养护理管理者领导力、建立有效激励机制、构建支持性工作环境、打造磁性医院关爱文化等,增强临床护士凝聚力.比较实施前后护士职业价值观、离职意愿及离职率状况.结果 实施磁性医院管理实践后,临床护士职业价值观评分显著高于实施前,离职意愿评分显著低于实施前(均P<0.05);离职率由2017年33.05%降至2020年6.19% (P<0.01).结论 磁性医院管理能引导临床护士建立正确的职业价值观,降低护士离职意愿及离职率.  相似文献   
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IntroductionIntracranial aneurysm coil embolisation is a fluoroscopically guided procedure associated with high radiation dose. The increase in the number of coil embolisation procedures raises concern for the amount of radiation and the associated radiation risks to the patients. This research study was conducted to determine the average radiation dose to patients’ thyroid glands and local skin during intracranial aneurysm coil embolisation and to establish preliminary local diagnostic reference levels for this procedure. In this paper, local skin dose refers to the absorbed radiation dose on the areas of the skin exposed to radiation during intracranial aneurysm coil embolisation, namely neck, face and scalp.MethodsThis study employed air-kerma area product meters to determine the local skin dose and diagnostic reference levels during intracranial aneurysm coil embolisation. In addition, thyroid radiation doses were measured using thermo-luminescent dosimeters on a phantom during simulation of embolisation procedures.ResultsThe local skin doses as determined by air-kerma area product ranged between 33 and 125 Gy.cm2. The mean thyroid dose was 9.87 mGy. The established local diagnostic reference level was 52.1 Gy cm2, 17.8 min’ fluoroscopy time and 503 image frames.ConclusionThe average air-kerma area product values and the proposed diagnostic reference levels were lower than most published values for intracranial aneurysm coil embolisation.Implications for practiceThe established local diagnostic reference levels are recommended for use as radiation dose optimisation tool at the research site. The findings of this study cannot be generalised or applied to other hospitals. The complexity of the embolisation procedures was not classified for this study. Further research on diagnostic reference levels for intracranial aneurysm coil embolisation, taking into account the complexity of the procedures, is recommended.  相似文献   
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