首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2451篇
  免费   117篇
  国内免费   45篇
耳鼻咽喉   11篇
儿科学   10篇
妇产科学   217篇
基础医学   110篇
口腔科学   108篇
临床医学   459篇
内科学   75篇
皮肤病学   20篇
神经病学   9篇
特种医学   84篇
外国民族医学   1篇
外科学   342篇
综合类   348篇
预防医学   476篇
眼科学   10篇
药学   174篇
中国医学   128篇
肿瘤学   31篇
  2024年   5篇
  2023年   30篇
  2022年   32篇
  2021年   61篇
  2020年   71篇
  2019年   65篇
  2018年   43篇
  2017年   80篇
  2016年   87篇
  2015年   79篇
  2014年   186篇
  2013年   162篇
  2012年   219篇
  2011年   201篇
  2010年   152篇
  2009年   107篇
  2008年   115篇
  2007年   113篇
  2006年   132篇
  2005年   88篇
  2004年   72篇
  2003年   72篇
  2002年   56篇
  2001年   36篇
  2000年   45篇
  1999年   41篇
  1998年   21篇
  1997年   21篇
  1996年   26篇
  1995年   23篇
  1994年   22篇
  1993年   19篇
  1992年   14篇
  1991年   14篇
  1990年   18篇
  1989年   8篇
  1988年   14篇
  1987年   8篇
  1986年   5篇
  1985年   8篇
  1984年   11篇
  1983年   2篇
  1982年   10篇
  1981年   3篇
  1980年   3篇
  1979年   3篇
  1978年   6篇
  1975年   1篇
  1974年   1篇
  1973年   1篇
排序方式: 共有2613条查询结果,搜索用时 15 毫秒
1.

Objectives

To identify barriers to postpartum permanent contraception procedures after vaginal delivery and to explore contraceptive and reproductive outcomes of women who experience unfulfilled requests.

Study design

We performed a retrospective cohort study of women requesting postpartum permanent contraception after vaginal delivery from 7/1/11 to 6/30/14 at Strong Memorial Hospital in Rochester, NY. We ascertained patient characteristics and outcomes through electronic medical records and birth certificate data search.

Results

Of 189 women in our sample, 78 (41.3%) had a postpartum permanent contraception procedure. Factors associated with unfulfilled requests in adjusted analysis included BMI ≥40 (OR 3.71, 95% CI 1.46–9.48 compared to BMI <35), federal sterilization consent signed ≥36 weeks (OR 5.10, 95% CI 1.64–15.86 compared to <36 weeks) and delivery in the latter half of the week (Wednesday–Saturday) (OR 2.02, 95% CI 1.08–3.79). Documented reasons for unfulfilled permanent contraception requests included patient changing her mind related to procedural issues (21, 18.9%), invalid consent (20, 18.0%), maternal obesity (17, 15.3%), lack of operating room availability (14, 12.6%) and ambivalence about permanent contraception (5, 4.5%). Of 57 women who planned for interval permanent contraception and had institutional follow-up over the subsequent year, 14 (24.6%) had a procedure, 8 (14.0%) initiated long-acting reversible contraception, and 13 (22.8%) became pregnant.

Conclusions

Fewer than half of women obtained desired postpartum permanent contraception after vaginal delivery, with logistical issues and obesity being the most common reported barriers. Health care providers should advocate for access to postpartum permanent contraception, as well as discuss prenatally the individualized probability of nonfulfillment and importance of alternative contraceptive plans.

Implications

Logistical barriers and inappropriate antenatal preparation contribute to the fact that over half of women do not obtain desired postpartum permanent contraception after vaginal delivery. To respect reproductive autonomy and improve care, clinicians and other health officials should eliminate barriers to immediate postpartum permanent contraception while increasing access to alternative options.  相似文献   
2.
BACKGROUND Esophagogastric leakage is one of the most severe postoperative complications.Partial disruption of the anastomosis,can be successfully treated with an endoscopic vacuum assisted closure(E-VAC).The advantage of that method of treatment is the ability to adjust a vacuum dressing individually to the size of the dehiscence and thus to reduce the risk of a secondary fistula or abscess.The authors present two patients with postoperative gastroesophageal leakage treated successfully with E-VAC.CASE SUMMARY Two male patients developed a potentially life threatening esophagogastric leakage.Patient A underwent resection of the distal half of the esophagus and upper part of the stomach due to Siewert type II adenocarcinoma of the gastroesophageal junction.Proximal resection of the stomach was performed in the patient B after massive bleeding from Mallory-Weiss tears.Both patients were treated successfully with an individually adapted E-VAC with concomitant correction of fluid and electrolyte disturbances,and treatment of sepsis with appropriate antibiotics.CONCLUSION Endoscopic vacuum closure is an effective alternative to endoscopic stenting or relaparotomy.Through individual approach it allows a more accurate assessment of healing.  相似文献   
3.
PurposeTo retrospectively compare three-dimensional ultrasonography (3D-US) and pelvic X-rays to assess the position of tubal sterilization microinserts.Material and methodsForty-four patients who underwent tubal sterilization with Essure® microinserts in our institution were included. The microinserts’position was evaluated three months after the procedure using 3D-US and pelvic X-rays. Placement on 3D-US was binary categorized as correct or incorrect and the distance between the two devices was reported. The orientation and symmetric deployment of the microinserts and the distance between the proximal parts of the two devices was assessed on pelvic X-rays. Performance of 3D-US and pelvic X-ray were compared using Mac Nemar test. Comparison of the distance between the two devices measured on pelvic X-rays and 3D-US was made with the paired Student t test.Results3D-US images showed microinserts in 93% (41/44). Eighty-six percent (38/44) were correctly positioned on 3D-US and 82% (36/44) on pelvic X-rays. No significant differences between the performances of the two imaging techniques were found. No significant differences for the distance between the two devices measured on pelvic X-ray and 3D-US was found.Conclusion3D-US is a simple, non-ionizing technique, which appears as a promising alternate technique to pelvic X-rays to assess the correct position of Essure® microinserts.  相似文献   
4.
目的:探讨负压创面治疗技术(Vacuum assisted closure,VAC)结合游离植皮治疗儿童大面积皮肤缺损疗效及对患儿生活质量的影响。方法:选取2015年2月-2019年2月笔者医院收治的60例大面积皮肤缺损患儿作为研究对象,按照随机数表法分为干预组和对照组,每组30例。对照组采用游离植皮术治疗,干预组在对照组的基础上结合VAC治疗,以皮片成活时间、皮片成活率、换药次数及住院天数评估疗效,以长海痛尺分级法评估患儿疼痛等级,以抑郁自评量表(Self-rating depression scale,SDS)、焦虑自评量表(Self-rating anxiety scale,SAS)评估患儿心理状态,以术后不良反应发生率评估患儿预后情况,以自制生活质量表评估患儿生活质量水平。结果:干预组患儿皮片成活时间、换药次数与住院天数均小于对照组,差异有统计学意义(P<0.05)。干预组患儿皮片成活率为93.33%高于对照组的76.67%,差异有统计学意义(P<0.05)。干预组治疗后疼痛感、SDS与SAS评分低于治疗前,且低于对照组,差异有统计学意义(P<0.05)。干预组患儿术后不良反应发生率为6.67%显著低于对照组23.33%,差异有统计学意义(P<0.05)。两组治疗前活动能力、心理健康及社交能力均低于治疗后,干预组治疗后活动能力、心理健康及社交能力均高于对照组(P<0.05)。结论:VAC结合游离植皮治疗儿童大面积皮肤缺损疗效显著,能有效降低患儿生理疼痛与心理焦虑,减少伤口感染等不良反应的发生,提高患儿生活质量,具有推广价值。  相似文献   
5.
目的 了解目前国内消化内镜超声探头的清洗消毒现状及存在的问题。方法 采用问卷调查的方式对全国范围内37所医院的消化内镜超声探头清洗和消毒灭菌情况进行调查。结果 70.27%的医院内镜超声探头数量为1~3条,奥林巴斯品牌最多(72.97%),48.65%的医院内镜中心每日使用探头的患者例数为0~5例;83.78%的医院采用专人清洗消毒内镜超声探头,人员主要以护理员为主(51.35%);清洗方法以"酶洗-擦洗-擦干"为主(89.19%),清洗时间以>1 min为主(62.16%);83.78%的医院内镜超声探头消毒方式为化学消毒剂浸泡,其中以邻苯二甲醛(70.27%)和全浸泡消毒(48.65%)为主;消毒时间以≥ 5 min为主(56.76%);27.03%的医院对内镜超声探头进行灭菌,其中以"一用一灭菌"(21.62%)和过氧乙酸浸泡10 min(10.81%)为主;消毒灭菌后的内镜超声探头主要放置在内镜储存柜(56.76%);78.38%的医院对当日拟使用的内镜超声探头进行再次消毒;56.76%的医院从未对消毒后的内镜超声探头进行消毒效果监测。结论 37所医院对内镜超声探头清洗和消毒灭菌情况存在一定差异,建议尽快制定内镜超声探头清洗消毒相关国家标准,规范内镜超声探头的清洗消毒流程。  相似文献   
6.
7.

Introduction

Forced and coerced sterilization is an internationally recognized human rights violation reported by women living with HIV (WLHIV) around the globe. Forced sterilization occurs when a person is sterilized without her knowledge or informed consent. Coerced sterilization occurs when misinformation, intimidation tactics, financial incentives or access to health services or employment are used to compel individuals to accept the procedure.

Methods

Drawing on community-based research with 285 WLHIV from four Latin American countries (El Salvador, Honduras, Mexico and Nicaragua), we conduct thematic qualitative analysis of reports of how and when healthcare providers pressured women to sterilize and multivariate logistic regression to assess whether social and economic characteristics and fertility history were associated with pressure to sterilize.

Results

A quarter (23%) of the participant WLHIV experienced pressure to sterilize post-diagnosis. WLHIV who had a pregnancy during which they (and their healthcare providers) knew their HIV diagnosis were almost six times more likely to experience coercive or forced sterilization than WLHIV who did not have a pregnancy with a known diagnosis (OR 5.66 CI 95% 2.35–13.58 p≤0.001). WLHIV reported that healthcare providers told them that living with HIV annulled their right to choose the number and spacing of their children and their contraceptive method, employed misinformation about the consequences of a subsequent pregnancy for women''s and children''s health, and denied medical services needed to prevent vertical (mother-to-child) HIV transmission to coerce women into accepting sterilization. Forced sterilization was practiced during caesarean delivery.

Conclusions

The experiences of WLHIV indicate that HIV-related stigma and discrimination by healthcare providers is a primary driver of coercive and forced sterilization. WLHIV are particularly vulnerable when seeking maternal health services. Health worker training on HIV and reproductive rights, improving counselling on HIV and sexual and reproductive health for WLHIV, providing State mechanisms to investigate and sanction coercive and forced sterilization, and strengthening civil society to increase WLHIV''s capacity to resist coercion to sterilize can contribute to preventing coercive and forced sterilization. Improved access to judicial and non-judicial mechanisms to procure justice for women who have experienced reproductive rights violations is also needed.  相似文献   
8.
9.
The progressive status of some selected small dental cutting instruments was examined from the time of their unpackaging through routine institutionalized cleaning and sterilizing procedures both before and after first and subsequent use. The cleaning protocol in place at the time involved a phosphoric acid based detergent and ultrasonic cleaning. All assessments were made by scanning electron microscopy. It was found that new burs as unpackaged are unacceptable for use without first being subjected to a cleaning process and that the cleaning procedure utilized was ineffective and unsuitable. Also observed was the potential for gross contamination; the need for subsequent ultrasonic cleaning; and the different rate and nature of deterioration, with use, of the three bur types studied. This study has led to the introduction of modified procedures for the physical cleaning of small cutting instruments in our institution and confirms the usefulness of the scanning electron microscope in the ongoing practice of quality assurance.  相似文献   
10.
Autoclaving is the absolute method of achieving instrument sterilization in any health care setting. However, it does rely on an effective pre-sterilization routine for instrument handling and the subsequent correct loading and operation of the autoclave. This paper addresses the issue of correct autoclave use, the causes of failures and the regular monitoring.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号