全文获取类型
收费全文 | 16351篇 |
免费 | 1298篇 |
国内免费 | 446篇 |
专业分类
耳鼻咽喉 | 89篇 |
儿科学 | 266篇 |
妇产科学 | 136篇 |
基础医学 | 3310篇 |
口腔科学 | 406篇 |
临床医学 | 1508篇 |
内科学 | 2736篇 |
皮肤病学 | 240篇 |
神经病学 | 2097篇 |
特种医学 | 333篇 |
外国民族医学 | 2篇 |
外科学 | 1226篇 |
综合类 | 1803篇 |
现状与发展 | 3篇 |
预防医学 | 629篇 |
眼科学 | 347篇 |
药学 | 1685篇 |
3篇 | |
中国医学 | 643篇 |
肿瘤学 | 633篇 |
出版年
2024年 | 13篇 |
2023年 | 242篇 |
2022年 | 287篇 |
2021年 | 568篇 |
2020年 | 499篇 |
2019年 | 541篇 |
2018年 | 546篇 |
2017年 | 512篇 |
2016年 | 509篇 |
2015年 | 498篇 |
2014年 | 923篇 |
2013年 | 1061篇 |
2012年 | 834篇 |
2011年 | 931篇 |
2010年 | 749篇 |
2009年 | 768篇 |
2008年 | 829篇 |
2007年 | 734篇 |
2006年 | 677篇 |
2005年 | 700篇 |
2004年 | 557篇 |
2003年 | 470篇 |
2002年 | 354篇 |
2001年 | 357篇 |
2000年 | 313篇 |
1999年 | 307篇 |
1998年 | 255篇 |
1997年 | 290篇 |
1996年 | 230篇 |
1995年 | 272篇 |
1994年 | 276篇 |
1993年 | 227篇 |
1992年 | 185篇 |
1991年 | 189篇 |
1990年 | 157篇 |
1989年 | 146篇 |
1988年 | 119篇 |
1987年 | 103篇 |
1986年 | 81篇 |
1985年 | 181篇 |
1984年 | 143篇 |
1983年 | 107篇 |
1982年 | 92篇 |
1981年 | 79篇 |
1980年 | 66篇 |
1979年 | 41篇 |
1978年 | 21篇 |
1977年 | 22篇 |
1976年 | 13篇 |
1972年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
2.
Sounak Gupta Rafael E. Jimenez Loren Herrera-Hernandez Christine M. Lohse R. Houston Thompson Stephen A. Boorjian Bradley C. Leibovich John C. Cheville 《Mayo Clinic proceedings. Mayo Clinic》2021,96(6):1470-1489
ObjectiveTo study the clinical features and identify unique renal neoplasia subtypes and their prognostic implications in individuals with tuberous sclerosis complex (TSC).Patients and MethodsThe Mayo Clinic nephrectomy registry included 37 patients with TSC diagnosed between 1970 and 2018. Four additional patients were identified from the pathology consultation and autopsy files. All available renal tumors were further characterized using immunohistochemistry and fluorescence in situ hybridization. Clinicopathologic features and follow-up were obtained from the medical record. The American Association for Cancer Research Project GENIE registry was accessed using cBioPortal for molecular profiling of angiomyolipoma (AML).ResultsA total of 276 renal tumors from 41 patients were analyzed. Renal tumors were classified into 9 distinct morphological subtypes, with AML predominating (238 [86%]). Interestingly, all these tumors acted in a benign fashion except one renal cell carcinoma with clear cells and fibromyomatous stroma and one epithelioid AML that metastasized. Molecular profiling studies revealed that epithelioid AMLs were enriched for alterations of TP53, RB1, and ATRX. Eight patients died of direct complications of TSC, including 3 of end-stage renal disease. To date, none have died of a renal epithelial neoplasm.ConclusionThe identification of unique renal neoplasia subtypes may provide important clues to establish a diagnosis of TSC, and in the somatic setting, this finding has important implications for accurate prognostication. These tumors tend to be indolent, and only 2 of 276 tumors in our study exhibited metastatic behavior. Our results support multidisciplinary management with a focus on preservation of renal function. 相似文献
3.
4.
5.
6.
目的探讨不同手术方法治疗复杂胫骨平台骨折临床疗效。方法选择2016年1月—2018年12月84例复杂胫骨平台骨折患者,随机分组。单侧锁定钢板内固定组选择单侧锁定钢板内固定手术,双侧切口双侧解剖钢板内固定组选择双侧切口双侧解剖钢板内固定。分析手术操作时间、手术失血、平均住院天数以及复杂胫骨平台骨折愈合时间;治疗前后患者视觉模拟评分和Rasmussen膝关节功能评分;膝关节僵硬发生率。结果双侧切口双侧解剖钢板内固定组视觉模拟评分和Rasmussen膝关节功能评分、手术操作时间、手术失血、平均住院天数以及复杂胫骨平台骨折愈合时间、膝关节僵硬发生率和单侧锁定钢板内固定组比较有优势,P<0.05。结论复杂胫骨平台骨折患者实施双侧切口双侧解剖钢板内固定可获得较好效果。 相似文献
7.
8.
Yang Luan Yan Zhang Kai Cui Fan Li Baolong Qin Yajun Ruan Kun Tang Hongyang Jiang Hao Li Xiaoyi Yuan Zhuo Liu Xiaming Liu Gan Yu Shengfei Xu Ruibao Chen Huan Yang Xiaolin Guo Xiaoyong Zeng Zhong Chen Zhiqiang Chen Zhiquan Hu Xiaodong Song Zhihua Wang Shaogang Wang Jihong Liu Tao Wang 《Translational andrology and urology》2021,10(1):466
BackgroundTo introduce and determine the value of optimized strategies for the management of urological tube-related emergencies with increased incidence, complexity and operational risk during the global spread of coronavirus disease 2019 (COVID-19).MethodsAll emergent urological patients at Tongji Hospital, Wuhan, during the period of January 23 (the beginning of lockdown in Wuhan) to March 23, 2020, and the corresponding period in 2019 were recruited to form this study’s COVID-19 group and control group, respectively. Tongji Hospital has the most concentrated and strongest Chinese medical teams to treat the largest number of severe COVID-19 patients. Patients in the control group were routinely treated, while patients in the COVID-19 group were managed following the optimized principles and strategies. The case incidence for each type of tube-related emergency was recorded. Baseline characteristics and management outcomes (surgery time, secondary complex operation rate, readmission rate, COVID-19 infection rate) were analyzed and compared across the control and COVID-19 periods.ResultsThe total emergent urological patients during the COVID-19 period was 42, whereas during the control period, it was 124. The incidence of tube-related emergencies increased from 53% to 88% (P<0.001) during the COVID-19 period. In particular, the incidence of nephrostomy tube-related (31% vs. 15%, P=0.027) and single-J stent-related problems (19% vs. 6%, P=0.009) increased significantly. The mean surgery times across the two periods were comparable. The number of secondary complex operations increased from 12 (18%) to 14 (38%) (P=0.028) during the COVID 19-period. The number of 2-week postoperative readmission decreased from 10 (15%) to 1 (3%) (P=0.049). No participants contracted during the COVID-19 period.ConclusionsUrological tube-related emergencies have been found to have a higher incidence and require more complicated and dangerous operations during the COVID-19 pandemic. However, the optimized management strategies introduced in this study are efficient, and safe for both urologists and patients. 相似文献
9.
10.