首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   3篇
  完全免费   2篇
  综合类   5篇
  2015年   1篇
  2014年   1篇
  2012年   1篇
  2004年   1篇
  2003年   1篇
排序方式: 共有5条查询结果,搜索用时 31 毫秒
1
1.
目的 :研究依据临床指征拔除气管导管后罗库溴铵、维库溴铵和阿曲库铵的肌松残留情况。方法 :6 0例择期手术患者随机分成维库溴铵 (VEC)、罗库溴铵 (ROC)及阿曲库铵 (ATR)三组 ,每组 2 0例。静吸复合麻醉。肌松药首量 :VEC组 12 0 μg/kg ;ROC组 6 0 0 μg/kg ;ATR组 5 0 0 μg/kg。术中用四个成串刺激 (TOF)监测肌松 ,当其值 (TOFR)至 0 .1时追加肌松药 1×ED 95。结果 :维库溴铵末次给药作用时间长于罗库溴铵 (P <0 .0 1)和阿曲库铵 (P <0 .0 5 ) ;拔管时各组TOFR及TOFR <0 .75的例数均无统计学差异 (P >0 .0 5 )。阿曲库铵残留时间短于维库溴铵 (P <0 .0 1)和罗库溴铵 (P <0 .0 5 )。结论 :非去极化肌松药罗库溴铵与维库溴铵和阿曲库铵一样 ,用药后若依据临床指征拔除气管导管都有发生术后肌松残留的危险。  相似文献
2.
氨基糖苷类抗生素对兔神经肌肉功能的抑制作用   总被引:2,自引:0,他引:2  
【目的】研究麻醉下兔的活体内氨基糖苷类抗生素阿贝卡星(ABK)、阿司霉素(ASTM)、异帕咪星(ISP)和奈替咪星(NTL)对神经肌肉接头的抑制作用。【方法】成年家兔30只,游离左前胫骨肌并切断远端肌腱并与肌张力换能器系统固定连接。游离左胫神经固定电刺激电极,刺激频率为0.1Hz,持续0.1ms,间隔10s的超强刺激单相矩形波,记录4种抗生素神经刺激下引起的肌肉单次肌颤收缩抑制的强度。【结果】静脉内分别注射DABK=40~200mg/kg,DASTM=80~400mg/kg,DISP=80~480mg/kg和DNTL=20~60mg/kg后,依赖剂量增加前胫骨肌单次肌颤抑制强度进行性减弱。半数有效量ED50值大小顺序为DED50,NTL=30.2mg/kg相似文献
3.
Background Recurarization has previously been described in the context of acute normovolemic hemodilution.The aim of this study was to investigate the impairment of recovery of neuromuscular function after re-transfusion of intraoperative salvaged blood in patients treated with rocuronium.Methods We enrolled 50 patients undergoing general anesthesia for lumbar surgery.Intraoperative blood salvage (IBS) was used in 30 patients (group Ⅰ); the remaining 20 comprised a control group (group C).Anesthesia was induced with fentanyl,midazolam,propofol and rocuronium.Rocuronium was infused to maintain neuromuscular blockade during surgery.Blood was collected from the operative field and re-transfused in the post-anesthesia care unit (PACU).Neuromuscular function was monitored using the train-of-four ratio (TOFr).Once the train-of-four ratio exceeded 90 in the PACU,neuromuscular function was evaluated every 5 minutes for 30 minutes.The TOFr and incremental recovery of TOFr from baseline were recorded.Salvaged blood was re-transfused at the beginning of the evaluation for patients in group Ⅰ,and afterwards for patients in group C.Blood gas analysis was assessed before anesthesia and in the PACU.Results Incremental recovery of TOFr from baseline was significantly less in group Ⅰ than controls at 25 minutes (6.1±3.2vs.9.1±3.2,respectively; P=0.001) and 30 minutes (7.1±3.2 vs.10.0±2.2,respectively; P=-0.001).There were no significant differences in gas exchange between the groups.Conclusions In patients who had received a rocuronium infusion during anesthesia,re-transfusion of salvaged blood significantly impaired recovery of neuromuscular function recovery in the PACU,but without significant impairment of respiratory function.  相似文献
4.
目的 观察全麻患者回到麻醉恢复室(PACU)的肌松残余情况.方法 选择接受全身麻醉非心脏手术、术后转入PACU的患者151例.麻醉诱导给予芬太尼和丙泊酚后,采用TOF-Watch(R) SX加速度肌松监测仪进行肌松监测定标,记录四个成串刺激(TOF)比值基础值.然后单次给予中效非去极化肌松药罗库溴铵或顺苯磺酸阿曲库铵,进行气管插管或放置喉罩.麻醉维持采用丙泊酚、瑞芬太尼静脉输注.术毕由麻醉医生根据临床指征拔管.记录患者从拔管到入PACU的时间.回到PACU即刻开始监测TOF值,每5 min一次,共监测30 min或直到TOF比值恢复至0.9以上.结果 145例患者完成观察.回到PACU后测量的TOF比值除以定标后的TOF基础值,为修正过的TOF比值(TOFr).TOFr< 0.9者(肌松残余组)61例(42.1%),在PACU中TOFr恢复到0.9以上所需时间为(12.3±8.5)min.肌松残余组中有36例进行了肌松拮抗,而非肌松残余组(TOFr≥0.9)有49例进行拮抗,差异无统计学意义(P=0.536).肌松残余组与非肌松残余组从拔管到PACU的时间差异有统计学意义[(13.4±6.5)min vs.(16.1±5.0)min,P=0.033],带管时间差异有统计学意义[(61.0±22.6)min vs.(97.1±52.9)min,P=0.002].肌松残余组和非肌松残余组使用罗库溴铵者分别为13例和28例,使用顺苯磺酸阿曲库铵者分别为48例和56例,使用不同肌松药患者间肌松残余发生情况的差异无统计学意义(x2=2.518,P=0.136).结论 肌松残余是PACU中常见的并发症.采用肌松监测仪可以有效评估患者肌松残余情况.拔管后1h内是肌松恢复的关键时期.  相似文献
5.