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目的:调查冠心病合并糖尿病患者护理依赖性情况,并分析其影响因素。方法:采用便利抽样法选择142例冠心病合并糖尿病患者为研究对象,使用护理依赖性量表(CDS)对患者的护理依赖性进行调查。结果:冠心病合并糖尿病患者CDS 总分为(44.85 ± 16.47)分,护理依赖发生率为 64.79%。文化程度、服药种类、是否了解病情、是否合并其他慢性疾病、是否行介入手术影响患者的护理依赖程度(P<0.05)。结论:冠心病合并糖尿病患者的护理依赖性发生率偏高,在护理过程中多关注文化程度低、服药种类多、不了解病情、合并其他慢性疾病及接受介入手术治疗的患者,制定合理的护理计划,实行有效的护理干预措施,以降低冠心病合并糖尿病患者的护理依赖性。 相似文献
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目的:探讨慢性酒依赖(CAD)患者失匹配负波(MMN)改变与其人格特征的关系。方法:采用改良的艾森克人格问卷(EPQ-R)对33例CAD患者(CAD组)和33名健康对照志愿者(对照组)进行评估,同时进行事件相关电位(ERP)检测,分析CAD患者MMN指标与其人格特征的关系。结果:CAD组EPQ-R中神经质(N)、精神质(P)和掩饰性(L)维度评分显著高于对照组(P<0.05或P<0.01);ERP各通道MMN潜伏期显著延长(P<0.05或P<0.01)。相关分析显示,CAD患者MMN指标与其人口学资料及人格特征无相关性。结论:CAD患者具有神经质、精神质的人格特征,其MMN潜伏期延长,但MMN改变与其人格特征无相关性。 相似文献
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《Clinical lung cancer》2020,21(2):171-176
BackgroundPatients with lung cancer continue to smoke owing to complex factors. Failure to quit smoking (defined as nicotine dependence) is significantly associated with genetic status. This study aimed to investigate the relationship between polymorphisms in nicotine dependence genes and smoking status after the diagnosis of lung cancer.Patients and MethodsA total of 240 patients with lung cancer were included from July 2017 to March 2018. According to the actual smoking condition after lung cancer diagnosis, eligible patients were divided into 3 groups: the never-smoking group, the failure to quit smoking group, and the successful smoking cessation group. Fagerstrom Test for Nicotine Dependence scores were used to evaluate the smoking status of each group. Three nicotine-dependent genes with 6 loci were detected.ResultsAmong the 240 patients, 86 were never-smokers, 51 failed to quit smoking, and 104 successfully quit smoking. The initial age of smoking in the failure to quit smoking group was significantly younger than those in the successful smoking cessation group (P = .001). There was a significant difference in the GG and AG and AA genotype distributions of CHRNA3 (rs578776) among the 3 groups (P = .003). There was also a significant difference in the distribution of CHRNA4 (rs2229959) genotypes among the 3 groups (P = .003). However, there was no significant difference in the genotype distribution of CHRNA5 (rs588765) among the 3 groups (P = .277).ConclusionsGene polymorphisms of CHRNA3 (rs578776) and CHRNA4 (rs1044396 and rs2229959) were associated with the success of smoking cessation after the diagnosis of lung cancer, which should be considered in the management of smoking cessation after patients are diagnosed with lung cancer. 相似文献
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Björn Delfs Ralf-Peter Kapsch Ndimofor Chofor Hui Khee Looe Dietrich Harder Björn Poppe 《Zeitschrift für medizinische Physik》2019,29(1):39-48
The frequently applied narrow and non-standard transverse dose profiles of intensity modulated photon-beam radiotherapy, lacking lateral secondary electron equilibrium, require the use of high-resolution dosimetry detectors, and small air-filled detectors are recommended as the reference detectors for cross-calibration of the high-resolution detectors. The present study focuses on the dosimetric properties of a novel cylindrical ionization chamber, the PTW Semiflex 3D 31021. The chamber's effective point of measurement was found to lie at (0.41 ± 0.04) r downstream the tip of the inner surface of the spherical front wall in the axial orientation and (0.46 ± 0.04) r upstream the chamber axis in the radial orientation. Due to its symmetrical design, the sigma values of its lateral dose response functions for all chamber's orientations are the same (2.10 ± 0.05 mm). The polarity correction factors obtained in this work do not exceed 0.1% and the saturation correction factor was below 1% up to a dose-per-pulse value of 0.956 mGy. The radiation quality correction factor kQ of the chamber as a function of the tissue-phantom-ratio, TPR20,10, has been calculated by Monte Carlo simulation and has been determined experimentally at the German Metrology Institute (Physikalisch-Technische Bundesanstalt, PTB). The values of the non-reference condition correction factor kNR have been Monte-Carlo-calculated for use of the chamber at various depths and field sizes. 相似文献
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IntroductionComputed tomography (CT) numbers are used in radiological diagnosis, attenuation correction and radiotherapy treatment planning. Modern CT scanners use iterative reconstruction methods instead of the traditional filtered back projection (FBP). Hence, the investigation of CT number accuracy with image reconstruction techniques and X-ray tube potential (kVp) used in CT is warranted. The aim of this study is to evaluate the effect of Sinogram Affirmed Iterative Reconstruction (SAFIRE) Technique and image acquisition at different tube potentials on CT numbers of different tissue equivalent materials.MethodsImages of the Computerised Imaging Reference System Model 062M Electron Density Phantom were acquired at different tube potentials and reconstructed using FBP and different strengths of SAFIRE. Average CT numbers, in circular regions of interest, and their standard deviations were used to investigate any dependence of CT numbers on tube potentials and/or image reconstruction technique using non-parametric statistical tests with p-values set at 0.05.ResultsStatistically significant differences in CT numbers were not observed (p > 0.091) between the different image reconstruction techniques. CT number of bone equivalent materials increased significantly (p < 0.015), by up to 400 Hounsfield Units, when tube potential was decreased. Such extent of CT number change over the tube potentials range used in this study may influence diagnostic outcomes in lung nodule, contrast enhanced and calcium score studies. For all other tissue equivalent materials, the CT number did not change significantly for different tube potentials. Linear relationship was observed between CT numbers and electron densities.ConclusionThe study concludes that the CT numbers of all tissues did not change significantly with image reconstruction methods. However, the CT numbers of bone equivalent materials increased with decreasing tube potentials, which may result in misrepresentation of clinical information obtained.Implications for practiceWhen CT images are used to extract quantitative parameters such as calcium score, to characterise lung nodules and contrast enhanced structures, the kVp used for image acquisition should be carefully selected to avoid any misrepresentation of clinical information. 相似文献
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John B. Whitfield Devanshi Seth Timothy R. Morgan GenomALC Consortium 《Alcoholism, clinical and experimental research》2022,46(12):2245-2257