多普勒超声Tei指数评价小儿病毒性心肌炎心功能的变化

目的通过超声测定左、右心室Tei指数评价小儿病毒性心肌炎心功能的变化的临床意义。方法对50例正常儿童,55例病毒性心肌炎患儿进行左、右心室Tei指数、射血分数(EF)等指标的测定。结果55例病毒性心肌炎患儿左、右心室Tei指数明显大于对照组(P<0.01)。结论应用超声Tei指数技术对病毒性心肌炎患儿心功能进行评价具较高敏感性,为临床提供了可靠的诊断依据。     

双腔起搏时Tei指数与常用优化房室延迟时间指标的对比研究

目的探讨Tei指数在双腔起搏器置入患者中对房室延迟(AVD)进行优化的价值。方法从首次安装双腔起搏器患者中选择12例,其中9例为病态窦房结综合征,3例为完全性房室传导阻滞。起搏器安装术后(7±3)个月对患者行超声心动图检查。本文以Tei指数优化AVD,与以左心室心输出量(LVCO)及左心室充盈时间(LVFT)常规优化的AVD进行比较,并对不同方法优化下的心功能参数进行比较。结果以LVCO和LVFT优化的AVD差异有统计学意义,AVD分别为(173.07±50.26)ms、(107.69±28.77)ms,P<0.01;Tei指数优化的AVD(157.69±57.17)ms介于以LVCO和LVFT优化的AVD之间;以Tei指数优化AVD时的LVCO与LVCO优化时的LVCO相比差异无统计学意义,LVCO分别为(3.41±0.47)L/min、(3.62±0.57)L/min,P>0.05;Tei指数优化AVD时的LVFT与LVFT优化时的LVFT相比差异亦无统计学意义,LVFT分别为(352.64±66.81)ms、(387.25±58.61)ms,P>0.05。结论Tei指数可以作为AVD优化的指标。     

Tei指数评估妊娠期糖尿病胎儿及其出生后整体心功能的价值

【】目的 探讨Tei指数评估妊娠期糖尿病(GDM)胎儿及其出生后整体心功能的价值。 方法 选取2015年1月-2016年6月我院收治的47例GDM血糖控制不良孕妇(A组)、55例GDM血糖控制良好孕妇(B组)、70例正常妊娠产妇(C组)作为研究对象,所有孕妇均为单胎妊娠。在入组时、分娩后1-7d、分娩后2-3月,采用多普勒超声心动图检测胎儿的左心室及右心室Tei指数。 结果 入组时、分娩后1-7d、分娩后2-3月,3组胎儿左心室Tei指数、右心室Tei指数相比差异均有统计学意义(P＜0.05)。同一个时间点组间进行比较：A组胎儿左心室Tei指数、右心室Tei指数均显著高于B组、C组胎儿(P＜0.05),B组、C组胎儿之间左心室Tei指数、右心室Tei指数相比差异无统计学意义(P＜0.05)。 结论 积极有效控制血糖可以避免GDM胎儿的心功能受损。血糖控制不良可以损害GDM胎儿心功能,即使胎儿分娩后2-3个月内其心功能仍然处于异常水平。     

Tei指数监测蒽环类药物对肿瘤患者心功能的影响

目的探讨心肌做功指数（myocardial performance index,MPI,又称Tei指数）在评价蒽环类药物（anthracy-cline,ATC）对肿瘤患者心功能早期损害方面的临床应用价值。方法测定并比较50例肿瘤患者ATC化疗前和化疗后6个月常规超声心动图参数及Tei指数参数。结果Tei指数各相关参数显示ATC化疗后左、右心室等容舒张时间（IRT、IRT′）较化疗前明显延长（P<0.05）;左、右心室等容收缩时间（ICT、ICT′）,左室及右室射血时间（ET、ET′）较化疗前无显著性差异,但左、右心室Tei指数较化疗前有显著性增加（P<0.05）。左室射血分数（LVEF）在化疗前后无显著性差异,仅14例（28%）患者化疗后出现常规左室舒张功能指标异常,其中4例（8%）同时并发右心室舒张功能指标异常。结论Tei指数能更早、更敏感地评价ATC对肿瘤患者心脏功能损害。     

Differentiation of left ventricular diastolic dysfunction, identification of pseudonormal/restrictive mitral inflow pattern and determination of left ventricular filling pressure by Tei index obtained from tissue Doppler echocardiography

BACKGROUND: Tei index obtained from tissue Doppler echocardiography (TDE-Tei index) has an inherent advantage of recording its systolic and diastolic components simultaneously on the same cardiac cycle. The aims of this study are to evaluate whether TDE-Tei index also exerts a correlation with left ventricular (LV) systolic and diastolic function and filling pressure and to see whether it can effectively identify the pseudonormal/restrictive mitral filling pattern. METHODS: Echocardiographic examination was performed in 243 consecutive patients. These patients were classified into three groups as normal, abnormal relaxation, and pseudonormal/restrictive groups according to the transmitral E/A-wave velocity (E/A), early diastolic velocity of lateral mitral annulus (Ea) and E/Ea. RESULTS: Standard Doppler indices of LV filling such as E, A, E/A, and E-wave deceleration time had a bimodal distribution, but Ea decreased and E/Ea and TDE-Tei index increased progressively with worsening of LV diastolic function. The sensitivity and specificity of TDE-Tei index>0.51 in the discrimination of pseudonormal/restrictive filling pattern were 85% and 96%, respectively. After stepwise multiple linear regression analysis, TDE-Tei index had a significant negative correlation with Ea (beta=-0.296, P<0.001) and ejection fraction (beta=-0.293, P<0.001) and positive correlation with E/Ea (beta=0.235, P=0.001). CONCLUSIONS: TDE-Tei index increased with worsening of LV diastolic function and can effectively identify the pseudonormal/restrictive mitral inflow pattern. It also correlated with the echocardiographic parameters of LV systolic and diastolic function and filling pressure. It suggests that TDE-Tei index is a simple and feasible marker in assessing global LV function.     

右室Tei指数评价左向右分流先天性心脏病患者右心室功能的价值

目的 探讨由超声组织多普勒测得的右分流心室Tei指数对左向右先天性心脏病(CHD)患者右心室功能的应用价值.方法 左向右分流CHD患者60例,其中35例为CHD伴有肺动脉高压组,25例为CHD不伴肺动脉高压组,33例为健康对照组.运用超声组织多普勒方法计算右室Tei指数,分析比较各组间Tei指数的差异.结果 CHD肺动...     

Myocardial performance index (Tei index) does not reflect long-term changes in left ventricular function after acute myocardial infarction

AIMS: To evaluate whether changes in myocardial performance index (MPI or Tei index) were related to changes in other Doppler echocardiographic parameters after acute myocardial infarction, or had any independent prognostic impact in a 2-year observational study. METHODS AND RESULTS: Seventy-one patients with acute myocardial infarction without heart failure were examined at baseline, 3 months, and 2 years. MPI was significantly related to end-diastolic and end-systolic volume indexes, ejection fraction, maximal velocity, and time velocity integral of early mitral filling wave at 3 months and 2 years. MPI did not contribute significantly to the prediction of any changes in the measures of diastolic or systolic function at 3 months or 2 years. Baseline MPI was significantly higher in patients who later developed heart failure(0.55 +/- 0.16)than in other patients(0.43 +/- 0.13, P = 0.006), but had no independent predictive power for the development of heart failure or death relative to end-systolic volume index and deceleration time of early mitral filling wave. CONCLUSION: MPI did not accurately reflect changes in Doppler and two-dimensional echocardiographic measures of diastolic or systolic function during a 2-year follow-up after acute myocardial infarction, and did not have any independent prognostic impact.     

Tei指数结合声学定量技术评价肝硬化患者左室功能的价值

目的探讨Tei指数结合声学定量技术评价肝硬化患者左心功能的临床价值。方法肝硬化组患者40例,按照Child-Pugh分级分为A级、B级、C级,体检健康者30例为对照组,脉冲多普勒测量其左室Tei指数及左室射血分数(EF),应用Qlab软件测量左房充盈分数(AFF)、左室快速充盈期峰值率(PRFA)。结果肝硬化患者左室Tei指数及AFF高于对照组,PRFA低于对照组(P0.05),其中Child C级患者Tei指数和AFF高于Child A级,EF和PRFA低于Child A级(P0.05)。结论 Tei指数结合声学定量技术优于传统方法评价肝硬化患者左心功能,为临床提供了检测肝硬化患者左室功能改变的新方法。     

心力衰竭患儿Tei指数与血浆肾上腺髓质素水平的相关性研究

目的探讨心力衰竭(CHF)患儿Tei指数与血浆肾上腺髓质素(ADM)水平的关系,评价ADM在小儿CHF中的临床意义。方法采集CHF患儿42例和正常对照组23例心尖四腔切面,组织多普勒技术分别测量二尖瓣环后间隔和左心室侧壁位点、三尖瓣环右心室游离壁位点的Tei指数,取3个位点Tei指数的均值作为心脏整体Tei指数。采用放射免疫法测定各组血浆ADM浓度。结果 CHF组Tei指数较对照组延长(P<0.05),治疗后Tei指数较治疗前缩短(P<0.01);CHF组血浆ADM水平高于对照组(P<0.05),治疗后血浆ADM水平较治疗前降低(P<0.01);CHF组血浆ADM浓度与Tei指数呈现高度相关性,而且与左心室射血分数、短轴缩短率也呈现高度相关性(P<0.001)。结论组织多普勒Tei指数测量便捷、安全,能全面反映CHF患儿的整体心脏功能;血浆ADM水平为临床上评价CHF提供准确信息。ADM水平与Tei指数呈显著相关性。