Under the influence of academic theories of numerous physicians of TCM such as Li Gao and Li Zhong-zi in antient China, Professor Jia Chun-sheng proposed the academic thought of tonifying spleen and kidney in combination with acupuncture based on his clinical experience for decades. In clinical practice of acupuncture, Zhōngwăn ( CV 12), bilateral Tiānshū ( ST 25), Qìhăi ( CV 6), Guānyuán ( CV4) are often selected to invigorate spleen so as to nourish original qi and to treat both spleen and kidney. The above-mentioned five acupoints form a pattern similar to a star according to their location distribution, so it is called the starlike selection method of acupoints, which attaches importance to spleen and kidney (original qi). Many diseases, especially internal injuries, are often treated with the starlike acupuncture manipulation combined with acupuncture at other acupoints, which achieves good clinical efficacy. 相似文献
Childhood rheumatic diseases (CRD) are chronic inflammatory conditions, often leading to severe functional impairment and disability. They produce high direct and indirect costs for patients, their families and society overall. Biologic treatment, adalimumab of note, has drastically changed the disease management, significantly decreasing morbidity, over childhood, and eventually lifelong. After 12 years of pediatric experience with adalimumab, safety data resulted of great interest. 相似文献
Despite the enormous progress in the treatment of juvenile idiopathic arthritis (JIA), innovations based on true bench-to-bedside research, performed in JIA patients, are still scarce. This chapter describes novel developments in which clinical innovations go hand in hand with basic discoveries. For the purpose of this review, we will mainly focus on developments in severe forms of JIA, most notably systemic JIA and polyarticular JIA. However, also in less severe forms of JIA, such as oligoarticular JIA, better insight will help to improve diagnosis and treatment. Facilitating the transition from bench to bedside will prove crucial for addressing the major challenges in JIA management.If successful, it will set new standards for a safe, targeted and personalized therapeutic approach for children with JIA. 相似文献
Purpose: The aim of this study is to assess the incidence, etiology, visual outcomes, and complication rates of pediatric uveitis patients at a dedicated multidisciplinary uveitis clinic in Northern Ireland.
Methods: Data were collected from charts of all patients attending the clinic at the Belfast Health and Social Care Trust between 2011 and 2015. Demographics, disease characteristics, treatments, visual acuity, and complications were recorded.
Results: There were 94 patients with uveitis onset before the age of 16 years. Etiology was mixed with JIAU the leading cause accounting for 48% of patients. Thirty-seven percent of patients had known complications at presentation and 65% by final visit. Systemic treatments were used in 65% of cases. Ninety-two percent of eyes had a final visual acuity ≥ 6/12 at a mean follow-up of 5 years.
Conclusions: The etiology of uveitis in this pediatric population is mixed. With close monitoring, most patients maintain good vision. 相似文献
Juvenile idiopathic arthritis (JIA) is the most common inflammatory joint condition of childhood and represents seven JIA subtypes characterised by distinct clinical and laboratory variables. Genetic and environmental factors are known to influence JIA, although many unanswered questions remain. Measurement of health outcomes in JIA is imperative for both clinical practice and research. Patient-reported outcomes present particular challenges in paediatric rheumatology in view of the importance of collecting reports from both the child/young person and the parent. Another challenge is the need for continuity of outcome measurement across the paediatric–adult interface during the process of transition in terms of both measurement tools and the mechanisms in the system to facilitate tracking of the young person into adult care. Finally, the need for adults with JIA to be seen as a distinct group in adult rheumatology practice is important for both service provision and outcome research. 相似文献