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CT扫描对股骨头坏死的诊断价值(CT片与X线片对比分析) 总被引:1,自引:0,他引:1
为了检验CT扫描对股骨头坏死的诊断价值,我们对病理证实的33例病人,42例股骨头坏死的X线平片与CT片进行了对比分析。37例股骨头坏死由CT扫描检出(88.1%),其中仅有26例股骨头坏死从X线平片中检出(61.9%)CT优于X线平片。但仍有5个早期股骨头坏死是靠放射核素扫描得以确诊,因而早期股骨头坏死CT扫描诊断尚存在一定限制。 相似文献
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Objective To investigate whether low-protein diet has protective effect on the progression of renal interstitial fibrosis in rats with cyclosporine A (CsA)-induced nephropathy. Methods Eighteen male Sprague-Dawley rats were randomly divided into three groups (6 rats in each group). The rats in control group (C group) received common diet; in model group (M group) low-salt diet; in intervention group (Ⅰ group) low-salt and low-protein diet. After diet adaptation period of one week, the rats in C group received subcutaneous injection of olive oil 1 mg/kg daily for 5 weeks, while M group and Ⅰ group subcutaneous injection of CsA (diluted into 25 g/L with olive oil) 1 ml/kg for 5 weeks. All the rats were sacrificed at the end of the 5th week. The food-intake and body weight were measured daily. The creatinine clearance (Ccr) was examined before rats were sacrificed. The semi-quantitative pathological analysis on kidney sections was performed. The mRNA and protein expression of transforming growth factor-β1 (TGF-βI) and type Ⅰ collagen (Col Ⅰ) in kidney tissue was determined with real time PCR and immunohistochemical staining, respectively. Results The food-intake and body weight of rats in M and I groups were significantly lower than those in C group (P<0.05). Compared with C group, the Ccr levels in M and Ⅰ groups were significantly reduced [(0.65±0.15) ml/min, (0.40+0.13) ml/min vs (1.55±0.29) ml/min, P<0.05], the relative fibrosis areas of kidney interstitium in M and I groups were significantly increased (3.60%±0.46%, 3.26%±0.75% vs 0.44%±0.24%, P<0.05), the mRNA and protein expression of TGF-β1 in M and I group was significantly up-regulated (by 2.6 and 3.1 times in mRNA and by 1.5 and 1.6 times in protein, respectively, P<0.05), and the mRNA and protein expression of Col Ⅰ in M and I groups was also significantly up-regulated (by 3.0 and 3.5 times in mRNA and by 2.3 and 2.1 times in protein, respectively, P<0.05). There were no significant differences between M and I groups in every parameters above-mentioned except the rat body weight and Ccr. Both the body weight and Ccr in Ⅰ group were significantly lower than those in M group (P<0.05). Compared with C group, the urine osmotic pressure in M group and in I group were deceased (for M group, P>0.05; for I group, P<0.05). Compared with C group, the serum cholesterol levels in M and I groups were significantly increased (P<0.05), and the serum phosphorus level in I group was significantly decreased (P<0.05). The levels of serum albumin and serum calcium of all three groups had no statistical differences (P>0.05). Conclusion Low-protein diet has no renoprutective effects on the rat model of cyclosporin A nephropathy, on the contrary, may induce body weight loss. 相似文献
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冬天,小宝宝刚从妈妈温暖的体内来到寒冷的世界,由于体温中枢发育不完善,抵御寒冷的能力很弱,如果不注意保暖,就可能引起肺炎、低体温、硬肿症等疾患,危害宝宝健康. 相似文献
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社会老年化是每个发达国家面临的现象,关爱老年人的身体健康是人人需要的。营养因素与人体的健康有密切关系。合理营养可以减少疾病、增进健康、延长寿命。老年人各系统的功能改变,尤其是许多功能的衰退,使老年人需要特别的营养需求。根据老年人的生理特点,归纳了老年人各类营养需求以及具体的膳食方案。 相似文献
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