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1.
多潘立酮干预早产儿喂养不耐受30例疗效观察   总被引:15,自引:0,他引:15  
目的探讨多潘立酮干预早产儿喂养不耐受的临床效果。方法54例喂养不耐受早产儿随机分为干预组30例和对照组24例。对照组给予保温、体位疗法、部分静脉营养等常规疗法。干预组在对照组治疗基础上口服或鼻饲多潘立酮混悬液0.2-0.3 ml.kg-1,每8 h 1次,喂奶前30 min给予,疗程3-5 d。结果干预组患儿病程和呕吐时间明显短于对照组(P<0.05),平均增加体重和每日增加奶量明显高于对照组(P<0.05);2组患儿均未出现明显不良反应。结论多潘立酮能提高早产儿喂养耐受性,且无明显副作用。  相似文献
2.
苯巴比妥早期干预早产儿黄疸66例   总被引:12,自引:1,他引:11  
目的观察苯巴比妥治疗早产儿黄疸的疗效。方法对照组给予光疗和茵枙黄注射液治疗,治疗组在对照组治疗的基础上给予苯巴比妥5 mg.kg-1.d-1,分3次口服,疗程7 d。结果治疗组总有效率明显高于对照组(P<0.01);治疗组经皮胆红素值和高胆红素血症发生率明显低于对照组(P<0.05,P<0.01)。结论苯巴比妥治疗早产儿黄疸疗效好,可以降低患儿血胆红素浓度,降低早产儿高胆红素血症的发生率。  相似文献
3.
早产极低出生体质量儿早期微量喂养   总被引:8,自引:2,他引:6  
目的为探讨早产儿的早期营养管理,采用微量喂养方法,研究其对早产极低出生体质量儿生长发育及其并发症发生的影响。方法76例早产极低出生体质量儿,均不能完全经口哺喂,无任何疾病。其中对照组36例采用常规管饲和(或)完全静脉营养。观察组40例在常规处理、对症支持治疗、静脉营养的基础上加用微量喂养,观察体质量变化、达足量喂养时间、喂养不耐受发生率、呼吸暂停发生率、胃肠排空便秘发生率、低血糖、高胆红素血征、坏死性小肠结肠炎发生率。结果观察组低血糖12例次,对照组13例次,2组比较无显著性差异(P>0.05),在恢复出生体质量时间、达足量喂养时间及喂养不耐受、呼吸暂停、便秘、坏死性小肠结肠炎的发生率和高胆红素血症等方面,观察组与对照组比较均有显著性差异(P<0.05)。结论早期微量喂养可以有效促进早产极低出生体质量儿的胃肠发育及功能成熟,减少并发症的发生,早期喂养,缓慢加奶,谨慎禁食在早产极低出生体质量儿早期管理中具有重要意义。  相似文献
4.
早期干预降低早产儿脑瘫发生率研究   总被引:7,自引:0,他引:7  
脑瘫作为一种运动性伤残,主要表现为运动发育落后,肌张力和姿势异常,主动运动减少或出现异常运动以及反射异常.脑瘫是婴儿出生后1个月内非进行性脑损伤所致的综合征,可伴有智力低下、惊厥、行为异常或感知觉障碍等.  相似文献
5.
Effect of parenteral glutamine supplementation in premature infants   总被引:7,自引:0,他引:7       下载免费PDF全文
Background Glutamine, proposed to be conditionally essential for critically ill patients, is not added routinely to parenteral amino acid formulations for premature infants and is provided in only small quantities by the enteral route when enteral feeding is low. Parenteral feeding is the basic way of nutrition in the first days of life of premature infants. In this study, we evaluated the effects of glutamine supplemented parenteral nutrition for premature infants on growth and development, feeding toleration, and infective episodes.Methods From December 2002 to July 2006, 53 premature infants were given either standard or glutamine supplemented parenteral nutrition for more than 2 weeks. Twenty-eight infants were in glutamine supplemented group, whose gestational age (31.4±2.0) weeks, birth weight range (1386±251) g; twenty-five infants were in control group, gestational age (31.1±1.7) weeks, with birth weight range (1346±199) g. There were no differences between the two groups. Various growth and biochemical indices were monitored throughout the duration of hospital stay. Data between groups were analyzed with Student’s t test. Nonparametric data were analyzed using a Chi-square test. A two-tailed P value &lt; 0.05 was considered statistically significant.Results The level of serum albumin was lower in the glutamine groups on the second week (3.0 vs 3.2 g/dl, P=0.028), and blood urea nitrogen was higher in glutamine groups on the fourth week (8.1 vs 4.9 mg/dl, P=0.014), but normal. Glutamine group infants took fewer days to regain birth weight (8.1 vs 10.4 days, P=0.017), required fewer days on parenteral nutrition (24.8 vs 30.8 days, P=0.035), with shorter stays in hospital (32.1 vs 38.6 days, P=0.047). Episodes of hospital acquired infection in glutamine supplemented infants were lower than that in control group (0.96 vs 1.84 times, P=0.000).Conclusion Parenteral glutamine supplementation in premature infants can shorten days on parenteral nutrition and length of stay in hospital, and decrease hospital acquired infection episodes.  相似文献
6.
早期干预对早产儿脑性瘫痪发生的影响   总被引:6,自引:0,他引:6  
目的探讨早期干预对降低早产儿脑性瘫痪(CP)发生的作用。方法2003年1月至2008年12月在三门峡市中心医院出生的450例早产儿,按家长意愿分为早期干预组(干预组)230例和常规育儿组(常规组)220例,2组早产儿出生后住新生儿重症监护病房给予保暖、静脉营养、预防感染、必要时给予吸氧等预防各种早产儿并发症常规治疗;常规组出院后接受常规育儿指导,不进行早期干预;干预组自出院开始,除接受常规育儿指导外,还进行早期干预,并重点进行按摩和主动运动训练,出现运动异常者做相应康复训练。结果1岁时,干预组发生CP 2例(0.87%),常规组发生CP 14例(6.36%),干预组CP发生率明显低于常规组,差异有统计学意义(P<0.05)。随访至2岁,干预组2例CP均属于轻度,常规组14例CP中7例为轻度,5例为中度,2例为重度。结论早期干预可降低CP发生率。  相似文献
7.
Background The severity of respiratory distress was associated with neonatal prognosis. This study aimed to explore the clinical characteristics, therapeutic interventions and short-term outcomes of late preterm or term infants who required respiratory support, and compare the usage of different illness severity assessment tools.Methods Seven neonatal intensive care units in tertiary hospitals were recruited. From November 2008 to October 2009, neonates born at ≥34 weeks' gestational age, admitted at 〈72 hours of age, requiring continuous positive airway pressure (CPAP) or mechanical ventilation for respiratory support were enrolled. Clinical data including demographic variables, underlying disease, complications, therapeutic interventions and short-term outcomes were collected. All infants were divided into three groups by Acute care of at-risk newborns (ACoRN) Respiratory Score 〈5, 5-8, and 〉8.Results During the study period, 503 newborn late preterm or term infants required respiratory support. The mean gestational age was (36.8±2.2) weeks, mean birth weight was (2734.5±603.5) g. The majority of the neonates were male (69.4%), late preterm (63.3%), delivered by cesarean section (74.8%), admitted in the first day of life (89.3%) and outborn (born at other hospitals, 76.9%). Of the cesarean section, 51.1% were performed electively. Infants in the severe group were more mature, had the highest rate of elective cesarean section, Apgar score 〈7 at 5 minutes and resuscitated with intubation, the in-hospital mortality increased significantly. In total, 58.1% of the patients were supported with mechanical ventilation and 17.3% received high frequency oscillation. Adjunctive therapies were commonly needed.Higher rate of infants in severe group needed mechanical ventilation or high frequency oscillation, volume expansion,bicarbonate infusion or vasopressors therapy (P 〈0.05). The incidence of complications was also increased significantly in severe group (P 〈0.05). The in-hospital mortality in the severe group was significantly higher than other two groups (P〈0.05). ACoRN Respiratory Score was correlated with Score for Neonatal Acute Physiology-Version Ⅱ (SNAP-Ⅱ) (P〈0.01). High gestational age, high SNAP-Ⅱ score and oxygenation index (OI), and Apgar score at 5 minutes 〈5 were independent risks for death.Conclusions Neonatal respiratory distress is still a common cause of hospitalization in China. Illness severity assessment is important for the management. ACoRN Respiratory Score which correlated with SNAP-Ⅱ score is easy to use and may be helpful in facilitating the caregivers in local hospital to identify the early signs and make the transfer decision promptly.  相似文献
8.
早产儿喂养不耐受影响因素分析   总被引:5,自引:0,他引:5  
目的探讨与早产儿喂养不耐受相关的危险因素。方法对我院2007年1月—12月收治的203例早产儿作回顾性分析。结果早产儿喂养不耐受的发生率为41.38%。喂养不耐受组胎龄和出生体质量较非喂养不耐受组明显低,差异有统计学意义(P〈0.05);宫内窘迫、窒息、宫内感染及呼吸机治疗率喂养不耐受组分别为65.48%、48.81%、46.43%、44.05%,显著高于非喂养不耐受组39.50%、25.21%、25.21%、29.41%(P〈0.05);胎龄小、出生体质量低、宫内窘迫和窒息是早产儿喂养不耐受的危险因素。结论早产儿喂养不耐受与多因素有关,预防产前及生后各危险因素,有利于改善早期胃肠道喂养耐受性。  相似文献
9.
早产低体重儿早期微量肠道喂养的临床观察   总被引:5,自引:0,他引:5  
早产儿因其自身特点易出现营养紊乱而影响其生长发育。虽然肠外营养在早产儿尤其是极低出生体重儿早期的营养支持方面起着较为重要的作用,但尽快达到经口喂养,完成肠外营养到肠内营养的过渡,是提高早产儿生存质量的关键。作者对某院2005-01/2007—03月收治的符合入选标准的25名早产儿,进行早期肠道喂养与临床观察,与该院2003—01/2004—12月新生儿病房住院的15名早产儿进行对比,现报告如下。  相似文献
10.
“鸟巢”在早产儿护理中的研究进展   总被引:5,自引:0,他引:5  
杨春凤  冼日凤 《医学综述》2008,14(14):2121-2123
随着医学科学的不断发展,早产儿能存活的体质量和胎龄越来越小,其生命质量越来越受到重视。早产儿从温暖的羊水、柔软的胎盘中提前娩出,被安置在暖箱中,四肢暴露于暖箱的空间中,缺乏安全感和舒适感。创造安全、舒适的犹如胎盘及子宫里的环境,可促进早产儿生长发育,有利于身心健康。鸟巢是医院特意给小宝宝们设置的人造子宫,是近年来用于早产儿护理的一种安全有效的方法,本文从鸟巢式护理的理论依据、作用及效果评价等方面进行综述。  相似文献
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