全文获取类型
收费全文 | 493篇 |
免费 | 42篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 4篇 |
妇产科学 | 8篇 |
基础医学 | 10篇 |
口腔科学 | 1篇 |
临床医学 | 97篇 |
内科学 | 24篇 |
神经病学 | 4篇 |
特种医学 | 14篇 |
外科学 | 21篇 |
综合类 | 163篇 |
预防医学 | 34篇 |
眼科学 | 36篇 |
药学 | 49篇 |
3篇 | |
中国医学 | 70篇 |
肿瘤学 | 11篇 |
出版年
2024年 | 5篇 |
2023年 | 32篇 |
2022年 | 18篇 |
2021年 | 18篇 |
2020年 | 22篇 |
2019年 | 12篇 |
2018年 | 19篇 |
2017年 | 20篇 |
2016年 | 22篇 |
2015年 | 18篇 |
2014年 | 24篇 |
2013年 | 44篇 |
2012年 | 55篇 |
2011年 | 33篇 |
2010年 | 37篇 |
2009年 | 25篇 |
2008年 | 23篇 |
2007年 | 35篇 |
2006年 | 22篇 |
2005年 | 15篇 |
2004年 | 20篇 |
2003年 | 9篇 |
2002年 | 5篇 |
2001年 | 7篇 |
2000年 | 2篇 |
1999年 | 5篇 |
1998年 | 3篇 |
1995年 | 1篇 |
1994年 | 1篇 |
排序方式: 共有552条查询结果,搜索用时 203 毫秒
1.
Objective To investigate anethol trithione therapic efficiency on dry eye. Methods It was a prospective random double-blind controlled study. Eighty cases diagnosed dry eye in Ocular Surface Out-patient Clinic of Xiamen University Affiliated Xiamen Eye Center from 2006 to 2008 were divided into two groups: anethol trithione group and control group, 40 cases in each group. Every group was then divided into two subgroups: weak dry eye subgroup, middle and severe dry eye subgroup. All groups had been added with 0.05% refresh drops. All patients had been detected and evaluated by subjective symptoms of dry eye, visual acuity,corneal fluorescent staining(F1), break-up time(BUT) and Schirmer Ⅰ test (SⅠT) at pre-therapy and 3,7,28 d of post-therapy. All groups had been compared and analyzed by F test and sample mean difference (SMD) or median difference (MD) comparison between pre-therapy and post-therapy. Results Except of tear and red eye, the other subjective symptoms of dry eye, F1, BUT and SⅠT of weak dry eye subgroup of both groups had been improved at 7 d after therapy. Only those of middle and severe dry eye subgroup of anethol trithione group had been improved at 7 d after therapy compared with those of pre-therapy: SMD=0.96 (visual tiredness), 1.26 (dry and unsmooth sensation), 0.82 (foreign body sensation), 1.28 (burning sensation), 1.05 (photophobia), 1.48 ( pain ) ; MD=0.30 (visual acuity), 4.00 (F1) ,5.00 (BUT), 5.00 (SⅠT) [F=15.30 (visual tiredness), 15.68 (dry and unsmooth sensation ), 13.56 (foreign body sensation), 20. 91 ( burning sensation ), 18.90 (photophobia), 27.22 ( pain ), 10.54 (visual acuity), 188.21 (F1) ,261.76 (BUT) ,269.05 (SⅠT) ;P<0. 05]. Those of middle and severe dry eye subgroup of control group hadn't significantly been improved at 28 d after therapy: SMD=0.10 (visual tiredness) ,0.16 (dry and unsmooth sensation) ,0.09 (foreign body sensation) ,0.38 ( burning sensation ), 0.24(photophobia) ,0.36 (pain) ,0.23 (red eye) ; MD=0.10 (visual acuity) ,0.50(F1) ,0.50(BUT), 0.50(SⅠT) [F=1.76 (visual tiredness), 1.61 (dry and unsmooth sensation), 1.02 (foreign body sensation),2.39 (burning sensation), 2.42 (photophobia), 2.73 ( pain ), 2.55 ( red eye ), 1.46 ( visual acuity) ,2.35 (F1) ,2.90 (BUT) ,2.76 (SⅠT) ; P>0.05]. SⅠT of anethol trithione group had been improved more significantly after therapy (F=13.77, P<0.05). Conclusion Anethol trithione could significantly improve middle and severe dry eye patients' symptoms and signs whose lacrimal gland function survival and it has clinical application value. 相似文献
2.
Objective To investigate anethol trithione therapic efficiency on dry eye. Methods It was a prospective random double-blind controlled study. Eighty cases diagnosed dry eye in Ocular Surface Out-patient Clinic of Xiamen University Affiliated Xiamen Eye Center from 2006 to 2008 were divided into two groups: anethol trithione group and control group, 40 cases in each group. Every group was then divided into two subgroups: weak dry eye subgroup, middle and severe dry eye subgroup. All groups had been added with 0.05% refresh drops. All patients had been detected and evaluated by subjective symptoms of dry eye, visual acuity,corneal fluorescent staining(F1), break-up time(BUT) and Schirmer Ⅰ test (SⅠT) at pre-therapy and 3,7,28 d of post-therapy. All groups had been compared and analyzed by F test and sample mean difference (SMD) or median difference (MD) comparison between pre-therapy and post-therapy. Results Except of tear and red eye, the other subjective symptoms of dry eye, F1, BUT and SⅠT of weak dry eye subgroup of both groups had been improved at 7 d after therapy. Only those of middle and severe dry eye subgroup of anethol trithione group had been improved at 7 d after therapy compared with those of pre-therapy: SMD=0.96 (visual tiredness), 1.26 (dry and unsmooth sensation), 0.82 (foreign body sensation), 1.28 (burning sensation), 1.05 (photophobia), 1.48 ( pain ) ; MD=0.30 (visual acuity), 4.00 (F1) ,5.00 (BUT), 5.00 (SⅠT) [F=15.30 (visual tiredness), 15.68 (dry and unsmooth sensation ), 13.56 (foreign body sensation), 20. 91 ( burning sensation ), 18.90 (photophobia), 27.22 ( pain ), 10.54 (visual acuity), 188.21 (F1) ,261.76 (BUT) ,269.05 (SⅠT) ;P<0. 05]. Those of middle and severe dry eye subgroup of control group hadn't significantly been improved at 28 d after therapy: SMD=0.10 (visual tiredness) ,0.16 (dry and unsmooth sensation) ,0.09 (foreign body sensation) ,0.38 ( burning sensation ), 0.24(photophobia) ,0.36 (pain) ,0.23 (red eye) ; MD=0.10 (visual acuity) ,0.50(F1) ,0.50(BUT), 0.50(SⅠT) [F=1.76 (visual tiredness), 1.61 (dry and unsmooth sensation), 1.02 (foreign body sensation),2.39 (burning sensation), 2.42 (photophobia), 2.73 ( pain ), 2.55 ( red eye ), 1.46 ( visual acuity) ,2.35 (F1) ,2.90 (BUT) ,2.76 (SⅠT) ; P>0.05]. SⅠT of anethol trithione group had been improved more significantly after therapy (F=13.77, P<0.05). Conclusion Anethol trithione could significantly improve middle and severe dry eye patients' symptoms and signs whose lacrimal gland function survival and it has clinical application value. 相似文献
3.
老年食管裂孔疝的X线诊断——附18例分析 总被引:1,自引:0,他引:1
目的 总结分析老年食管裂孔疝的X线诊断方法及其影像特征。方法 对18例老年食管裂孔疝患者分别进行上消化道钡餐透视和胸部平片检查,并就其X线诊断结果及影像特征作回顾性分析。结果 本组18例,钡餐透视检查阳性16例,阳性率88.9%,胸部平片检查15例,阳性3例,阳性率20.0%。其中,可复性裂孔疝6例,占33.3%,不可复性裂孔疝12例,占66.7%。结论 胸部平片检查简便易行,但阳性率低;钡餐透视检查阳性率高,其X线表现具有特征性,对老年食管裂孔疝的诊断具有重要意义。 相似文献
4.
5.
近年来,医院重医疗、轻教学,临床教师带教意识淡薄,加上社会因素的干扰,实习生提前介入考研、求职、择业,影响了临床教学质量。对此,广西桂林医学院针对存在的问题,进一步明确了办院思想,制定了临床教学质量评估标准,强化了临床教学管理,增强了带教意识,尤其是探讨了影响儿科教学质量的成因与对策,提高了临床教学质量。 相似文献
6.
MR扩散加权成像鉴别脑结核瘤及高级星形细胞瘤和脑转移瘤的价值 总被引:3,自引:0,他引:3
目的探讨MR扩散加权成像(DWI)在脑结核瘤、高级星形细胞瘤和脑转移瘤鉴别诊断中的价值。方法14例脑结核瘤、15例脑高级星形细胞瘤和21例脑转移瘤患者,在术前或接受治疗前行常规MRI和DWI。测量并计算3种疾病瘤体、瘤周围水肿带的平均表观扩散系数(ADC)值和病灶与对侧相应部位正常脑白质区ADC值的比值(rADC值)。结果脑结核瘤瘤体平均ADC值和rADC值分别为(1.2±0.2)×10^-3mm^2·s^-1和1.6±0.3,高级星形细胞瘤瘤体平均ADC值和rADC值分别为(0.8±0.1)×10^-3mm^2·s^-1和1.1±0.1,转移瘤瘤体平均ADC值和rADC值分别为(0.8±0.1)×10^-3mm^2·s^-1和1.0±0.2。3种疾病瘤体平均ADC值(F=33.57,P〈0.01)之间和rADC值(F=33.27,P〈0.01)之间差异均有统计学意义。脑结核瘤瘤周水肿带平均ADC值和rADC值分别为(1.8±0.1)×10^-3mm^2·s^-1和2.5±0.2,脑高级星形细胞瘤瘤周水肿带平均ADC值和rADC值分别为(1.4±0.2)×10^-3mm^2·s^-1和1.8±0.3,脑转移瘤瘤周水肿带平均ADC值和rADC值分别为(1.9±0.2)×10^-3mm^2·s^-1和2.3±0.5。3种疾病瘤周围水肿带平均ADC值(F=23.17,P〈0.01)之间和rADC值(F=5.94,P〈0.01)之间差异均有统计学意义。结论结合MRI、DWI检测方法,根据病灶瘤体和瘤周水肿带的ADC和rADC值可帮助鉴别脑结核瘤、脑高级星形细胞瘤和脑转移瘤。 相似文献
7.
支气管哮喘是威胁人们健康的慢性疾病,重症哮喘者对患者的身心健康造成的影响更严重。本文主要总结阐述如何进行有效地进行临床观察及对症护理。 相似文献
8.
9.
目的探讨出院计划对全喉切除患者主要照顾者的需求满足及生活质量的影响。方法使用随机数字表法将104例全喉切除患者的主要照顾者分为对照组和干预组,对照组51例,干预组53例。对照组使用常规护理,干预组在常规护理的基础上增加出院计划。比较两组照顾者在出院时、出院后1个月的需求满足及生活质量。结果干预组照顾者在患者出院时、出院后1个月的需求满足度评分和生活质量评分均高于对照组,差异具有统计学意义(P0.05)。结论出院计划可有效提高全喉切除患者照顾者的需求满足度和生活质量。 相似文献
10.