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风湿性心脏瓣膜病慢性心房颤动左房迷宫术五年随访 总被引:1,自引:0,他引:1
评价左房迷宫手术对风湿性心脏瓣膜病慢性心房颤动 (简称房颤 )治疗及心脏功能的远期影响。15例风湿性心脏瓣膜病伴慢性房颤同期施行心脏瓣膜手术和在心外膜标测指导下的左房迷宫手术 ,随访 5 9.2± 7.9个月。结果 :①心脏复跳后心外膜双房标测 11例显示窦性激动 ,4例为心房扑动。②术后 3个月 ,1,3,5年维持窦性心律者分别为 6 7% (10 / 15 ) ,80 % (12 / 15 ) ,86 .6 % (13/ 15 ) ,92 .8% (13/ 14 ) ,且不用任何抗心律失常药。③ 2例因窦性停搏 >3s ,安置永久起搏器。④随访期间左房容积 (76 .0 6± 2 0 .2 3cm3 vs 10 5 .5 1± 33.79cm3 ,P <0 .0 5 )、左房舒张内径(2 .79± 0 .5cmvs 3.6 7± 1.10cm ,P <0 .0 5 )、左室舒张内径 (4 .36± 0 .2 9cmvs4 .6 3± 0 .4 9cm ,P <0 .0 5 )、左室舒张末期容积 (86 .6 1± 14 .5 0cm3 vs 10 3.80± 2 4 .4 8cm3 ,P <0 .0 5 )、心输出量 (4 .6 0± 1.35L/minvs 5 .6 6± 0 .0 5L/min ,P <0 .0 5 )均明显小于术后。随访期射血分数 0 .6 6± 0 .0 7,左室内径短轴缩短率 35 .98%± 5 .39%。左房有收缩功能 87% ,右房有收缩功能 93%。⑤随访期再住院率 2 6 .6 %。结论 :风湿性心脏瓣膜病在换瓣同时进行左房迷宫术能安全有效的消除房颤 ,改善心脏功能和结构。 相似文献
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纤维蛋白封闭剂用于食管癌手术的临床分析 总被引:1,自引:0,他引:1
目的:探讨纤维蛋白封闭剂在食管癌根治术中的应用价值。方法:将食管癌患者62例,分为用胶组(27例)和未用胶组(35例),用胶组行常规食管癌根治术同时在手术创面应用纤维蛋白封闭剂,通过观察术后第12、24及48小时的胸腔闭式引流量及术后总引流量来确定纤维蛋白封闭剂在食管癌根治术中的有效性。结果:用胶组术后第12、24及48小时的胸腔闭式流量及术后总引流量均少于未用胶组,差异具有非常显著性(P<0.01)。结论:食管癌根治术中应用纤维蛋白封闭剂可以有效减少术后引流量,提早拔除胸腔闭式引流管,有利于患者的术后恢复。 相似文献
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Objective To determine the effects of hypoxia inducible factor-1α(HIF-1α) expression on postoperative adjuvant radiotherapy in esophageal carcinoma. Methods 95 cases with esophageal carcinoms who received radical operation were analyzed with followed-up data from 1995 to 1998.Expression of HIF-1α in 45 patients with esophageal carcinoma who received radiotherapy after radical operation were deternlined by immunohistochemical method in contrast with 50 patients with esophageal carcinoma received surgery alone.Kaplan-Meier method and COX proportional hazard model were used to analyze.Results The positive expression of HIF-1α in esophageal carcinoma was observed mainly in the nucleus of tumor cells.The positive expression rate of HIF-1α in esophageal carcinoma was 58.9%.The expression of HIF-1α had no relationship with age,sex,histologic subtype and T stage,but had positive relationship with recurrence and distant metastasis.There was significant difference between patients with positive and negative HIF-1α protein expression in surgery alone and postoperation radiotherapy group. COX model analysis showed that HIF-1α had separate and significant impacts on prognosis in surgery group and surgery plus radiotherapy group. Conclusion Over expression of HIF-1α protein suggests a poor prognosis,and has tendency to resist radiotherapy in esophageal carcinoma. 相似文献
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目的分析肺癌术后并发室上性心律失常(SA)的危险因素.方法回顾性分析自1999年3月至2004年8月行肺癌手术治疗患者199例,比较发生SA和未发生SA患者的临床资料,进行统计学分析,筛选高危因素(性别、年龄、切除部位、糖尿病、高血压病及吸烟史).结果肺癌术后SA的发生率为21.6%,其中心房颤动占(88.3%),SA发生的高发时间为第2天,年龄(≥65岁)、手术范围及术式SA组与非SA组比较,差异有统计学意义.结论 SA是肺手术常见的并发症,高龄、手术范围及术式是肺癌切除术后发生SA的危险因素. 相似文献
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目的 介绍食管后壁套入、前壁斜形食管胃吻合术。方法 采用食管后壁套入、前壁斜形食管胃吻合术治疗158例食管癌患者 ,其中胸内吻合 53例 ,颈部吻合 10 5例。结果 158例患者术后发生吻合口瘘 2例 ,占 1.3 % ;无一例吻合口狭窄。随诊结果满意。结论 食管后壁套入、前壁斜形食管胃吻合术治疗食管癌 ,并发症少 ,术后吻合口瘘发生率低 ,效果满意 相似文献