首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   92991篇
  免费   6757篇
  国内免费   1531篇
耳鼻咽喉   926篇
儿科学   1927篇
妇产科学   1122篇
基础医学   3560篇
口腔科学   4369篇
临床医学   14087篇
内科学   9874篇
皮肤病学   1496篇
神经病学   5658篇
特种医学   2282篇
外国民族医学   21篇
外科学   9344篇
综合类   15657篇
一般理论   4篇
预防医学   6120篇
眼科学   1485篇
药学   8527篇
  159篇
中国医学   9185篇
肿瘤学   5476篇
  2024年   52篇
  2023年   1428篇
  2022年   2015篇
  2021年   3392篇
  2020年   4074篇
  2019年   3242篇
  2018年   2889篇
  2017年   3199篇
  2016年   3203篇
  2015年   2915篇
  2014年   6534篇
  2013年   8795篇
  2012年   6125篇
  2011年   6809篇
  2010年   5706篇
  2009年   4997篇
  2008年   4505篇
  2007年   4715篇
  2006年   4201篇
  2005年   3714篇
  2004年   3001篇
  2003年   2664篇
  2002年   1955篇
  2001年   1578篇
  2000年   1353篇
  1999年   1080篇
  1998年   833篇
  1997年   725篇
  1996年   618篇
  1995年   574篇
  1994年   524篇
  1993年   455篇
  1992年   388篇
  1991年   338篇
  1990年   255篇
  1989年   254篇
  1988年   227篇
  1987年   216篇
  1986年   203篇
  1985年   263篇
  1984年   211篇
  1983年   144篇
  1982年   181篇
  1981年   153篇
  1980年   138篇
  1979年   124篇
  1978年   71篇
  1977年   65篇
  1976年   50篇
  1975年   33篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
通过对金水六君煎的相关资料进行整理研究,发现该方以二陈汤、贞元饮为基础创制, 尤其是在燥湿化痰时,增加熟地、当归温补真阴而治虚寒,突出反映调补元气,温脾固肾的制方思想。该方被张氏应用于19种病证,也被后世医家灵活加减,广泛使用。研究金水六君煎的配伍特点和制方思想,对后世理解张氏和法的含义,研究张氏温补真阴的学术思想,拓宽治疗痰喘的临床思路,有重要的实用价值和指导意义。   相似文献   
2.
随着低剂量螺旋电子计算机断层扫描(computed tomography,CT)应用于肺癌高危人群中的筛查越来越普及,肺外周病变(peripheral pulmonary lesions,PPLs)发现概率也随之增加。电磁导航支气管镜(electromagnetic navigation bronchoscopy,ENB)是一种能够进行肺部外周病变诊断、定位及治疗的工具,由于它的安全性和可靠性更高,ENB在未来有可能会改变肺部疾病的诊断和治疗方式,从而缓解病情甚至治愈肺癌,为肺癌的治疗开辟了新的路径。  相似文献   
3.
目的:调查伴牙周炎正畸患者的人格与焦虑情况,分析人格因素对成人正畸患者焦虑的影响。方法:在天津市口腔医院 正畸科2021年4—9月的成人复诊患者中,依据牙周炎诊断标准分组,收集牙周组(试验组)57例及牙周健康组(对照组)63 例, 共计120例患者。用艾森克人格简式量表(EPQ-RSC)和状态特质焦虑量表(STAI)进行封闭式自我评定,对两组人格及焦虑得 分进行比较,采用相关分析及层次回归分析对全部人格及焦虑得分进行分析。结果:(1)与对照组相比,试验组掩饰性人格得分 较高(Z=-3.317,P<0.01),其余人格及焦虑得分无显著差异(P>0.05)。(2)神经质人格(r=0.499,P<0.001)、状态焦虑(r=0.805, P<0.001)与特质焦虑呈正相关,内外向人格(r=-0.316,P<0.01)、掩饰性人格(r=-0.219,P<0.05)、文化程度(r=-0.188,P<0.05)与 特质焦虑呈负相关。(3)伴牙周炎正畸患者中神经质人格高分组对焦虑有预测作用(β=0.415,P<0.01),使牙周炎正畸患者导致特质 焦虑的神经质人格得分临界值为48.70。结论:伴牙周炎正畸患者掩饰性人格显著,神经质人格对特质焦虑起部分调节作用。  相似文献   
4.
目的检索并总结妇科恶性肿瘤下肢淋巴水肿患者的运动方案相关证据,为医护人员制订和规范下肢淋巴水肿的治疗和管理措施提供借鉴和参考。方法使用PIPOST工具明确循证问题,设置检索策略以及纳入和排除标准,系统检索国内外常见数据库中涉及妇科恶性肿瘤相关下肢淋巴水肿运动方面的指南、专家共识、系统评价、原始研究等证据,检索时间为建库至2021年3月31日,由2名经过循证护理系统培训的人员独立完成对文献的质量评价。结果共纳入16篇文献,其中5篇系统评价,4篇指南,4篇原始研究,3篇专家共识。从禁忌人群、运动评估、运动方案、运动强度、注意事项及健康宣教共6个方面汇总24条证据。结论汇总并分析了妇科恶性肿瘤下肢淋巴水肿患者运动方案的最佳证据,提供了具体建议,为规范运用和实践妇科恶性肿瘤相关下肢淋巴水肿患者的运动方案提供可靠的循证证据支持和参考意见,从而降低患者淋巴水肿的程度,提高其生活质量。  相似文献   
5.
《Australian critical care》2022,35(4):362-368
BackgroundThere are limited published data on physical activity of survivors of critical illness engaged in rehabilitation in hospital, despite it plausibly influencing outcome.ObjectiveThe aims of this study were to measure physical activity of patients with critical illness engaged in rehabilitation in the intensive care unit (ICU) and on the acute ward and report discharge destination, muscle strength, and functional outcomes.MethodsThis was a single-centre, prospective observational study. Adults with critical illness, who received ≥48 h of invasive mechanical ventilation, and who were awake and able to participate in rehabilitation were eligible. To record physical activity, participants wore BodyMedia SenseWear Armbands (BodyMedia Incorporated, USA), during daylight hours, from enrolment until hospital discharge or day 14 of ward stay (whichever occurred first). The primary outcome was time (minutes) spent performing physical activity at an intensity of greater than 1.5 Metabolic Equivalent Tasks. Secondary outcomes included discharge destination, muscle strength, and physical function.ResultsWe collected 807 days of physical activity data (363 days ICU, 424 days ward) from 59 participants. Mean (standard deviation) duration of daily physical activity increased from the ICU, 17.8 (22.8) minutes, to the ward, 52.8 (51.2) minutes (mean difference [95% confidence interval] = 35 [23.8–46.1] minutes, P < .001). High levels of activity in the ICU were associated with higher levels of activity on the ward (r = .728), n = 48, P < .001.ConclusionsPatients recovering from critical illness spend less than 5% of the day being physically active throughout hospital admission, even when receiving rehabilitation. Physical activity increased after discharge from intensive care, but had no relationship with discharge destination. Only the absence of ICU-acquired weakness on awakening was associated with discharge directly home from the acute hospital. Future studies could target early identification of ICU-acquired weakness and the preservation of muscle strength to improve discharge outcomes.  相似文献   
6.
ObjectivesThe purpose of this study was to investigate the prognostic weight of multimorbidity and functional impairment over long-term mortality among older patients discharged from acute care hospitals.DesignA prospective multicenter observational study.Setting and ParticipantsOur series consisted of 1967 adults aged ≥65 years consecutively admitted to acute care wards in Italy, in the context of the Report-AGE project.MethodsAfter signing a written informed consent, all patients underwent comprehensive geriatric assessment by Inter-RAI Minimum Data Set acute care. The primary endpoint of the present study was long-term mortality. Patients were grouped into 3 functional clusters and 3 disease clusters using the K-medians cluster analysis. The association of functional clusters, disease clusters, and Charlson score categories with long-term mortality was investigated through Cox regression analysis and the intercluster classification agreement was further estimated. Finally, the additive effect of either disease clusters or Charlson score on predictive ability of functional clusters was assessed by using changes in Harrell’s C-index and categorical Net Reclassification Index (NRI).ResultsFunctional clusters, disease clusters, and Charlson score were significant predictors of long-term mortality, but the interclassification agreement was poor. Functional clusters predicted mortality with greater accuracy [C-index 0.66, 95% confidence interval (CI) 0.65–0.68] compared with disease clusters (C-index 0.54, 95% CI 0.53–0.56), and Charlson score (C-index 0.58, 95% CI 0.56–0.59). Adding multimorbidity (NRI 0.23, 95% CI 0.14–0.31) or Charlson score (NRI 0.13, 95% CI 0.03–0.20) to functional cluster model slightly improved the accuracy of prediction.Conclusions and ImplicationsFunctional impairment may better predict prognosis compared with multimorbidity, which may be relevant to optimally address individuals’ needs and to design tailored preventive interventions.  相似文献   
7.
本文目的是对述情障碍的发生机制及干预对策进行综述,以期为述情障碍的临床治疗和研究提供新的方向.述情障碍不仅与多种心身疾病有关,也广泛存在于抑郁症、焦虑症和进食障碍等精神疾病中,严重影响患者生活质量.本文从认知、神经和社会心理因素三个层面对述情障碍及其在不同疾病下的发生机制进行综述,并总结干预对策,旨在为述情障碍的临床治疗提供参考.  相似文献   
8.
创伤性骨软骨损伤(OL)在临床中常见,骨软骨在解剖上涉及软骨表面和软骨下骨,其解剖和生理功能存在特殊性,临床上处理OL时必须同时兼顾软骨及软骨下骨。目前对创伤性OL的手术及非手术治疗仍存在较多争议。而骨软骨组织工程多层支架设计更接近关节软骨到软骨下骨不同层次的解剖特性,目前已作为一个理想的选择应用于临床,以期达到更好地修复创伤性OL的效果。本文从骨软骨单元的解剖、功能,骨软骨损伤病理生理机制、诊断、治疗方法等方面对创伤性OL进行系统总结,并对当前研究的组织工程支架在创伤性OL中的应用进展进行综述。  相似文献   
9.
The application of traditional Chinese medicines (TCMs) has a history of more than 2000 years, which have the characteristics of multi-component, multi-target, and high safety. Post-infectious cough (PIC) is a respiratory disease with high incidence. It belongs to subacute cough and accounts for as much as 40%–50%. Cough is the main clinical manifestation of PIC. PIC seriously affects people's life quality because of complex etiology, long-term course of disease, treatment difficulties and other characteristics. Western medicines are based on the principle of symptomatic treatment, so they are often difficult to control PIC fundamentally. These factors could due to that PIC is prolonged and unable to heal repeatedly. TCMs have obvious advantages in treating PIC, with accurate curative effects, less side effects and adverse reactions and are effective in improving PIC-related symptoms and indicators, enhancing patients' life quality and reducing pain. TCMs, guided by holistic concept and syndrome differentiation, advocate determine treatment on the basis of pattern types, and have remarkable clinical treatment effects. As for TCMs etiology, pathogenesis and syndrome types of PIC, TCM scholars have not yet reached a unified standard. However, most of them think that wind pathogen can cause PIC alone, or it can be combined with other evils, which might be the main mechanism of PIC. This paper discusses the advantages and limitations of TCMs in PIC treatment from etiology, pathogenesis, distribution of syndrome types and treatment of TCMs. This article focuses on the treatment methods and pharmacodynamic material basis of wind pathogen, providing ideas in treating PIC of TCMs clinically and innovative drug development.  相似文献   
10.
目的:探索不同功率的水冷激光对于不同种植体表面的影响。方法:收集临床上因种植体周围炎而拔除的不同表面种植体,分别用2、3、4 W 3种不同参数的水冷激光处理,通过扫描电镜(SEM)进行观察比较。结果:SLA?非亲水表面和INICELL?表面3~4 W的激光处理既能很好的去污又不会造成表面损伤;Tiunite?表面和国产MDIC种植体微弧氧化表面在2 W时去污效果欠佳,而3 W与4 W去污效果相当,4 W时会导致表面损伤。结论:随着功率的增大,水冷激光去污效果逐渐加强。不同激光参数对于不同种植体表面的影响不同,其中氧化类表面更易崩解,而喷砂酸蚀表面耐受激光的能力更强。  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号