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《Saudi Dental Journal》2022,34(8):730-737
BackgroundDentures with antimicrobial properties are desirable for preventing Candida albicans adhesion. This study was to assess the effectiveness of bioactive glass (BAG) on C. albicans adhesion, surface roughness, and hardness of denture base materials.MethodsHeat-polymerized (HP) and autopolymerized (AP) acrylic resins were used to fabricate 240 disk specimens (120/material, 60/C. albicans, 60/surface roughness and hardness). Specimens were divided into five groups (n = 10) based on the BAG concentration: 0.5, 1.5, 3, 5, and 7.5 wt% of the acrylic powder, with a control group comprised of unmodified specimens. Direct culture method was used to assess C. albicans adhesion. A profilometer and Vickers hardness test were used to measure surface roughness and hardness respectively. Analysis of variance (ANOVA) and post hoc Tukey’s test were used for data analysis (α = 0.05).ResultsBAG addition significantly decreased the C. albicans count when compared with the control group (P < 0.001) for both HP and AP. Regarding surface roughness, there was no change in the HP acrylic resins (P > 0.05), while the AP acrylic resins exhibited significantly higher surface roughness with BAG addition (P < 0.001). The hardness of the HP and AP acrylic resins were significantly higher with the addition of BAG (P < 0.001).ConclusionsThe addition of BAG to HP and AP acrylic resins effectively decreases C. albicans adhesion. The roughness of AP acrylic resins increases with the addition of BAG, while the hardness of both HP and AP acrylic resins increase with the addition of BAG. 相似文献
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目的:探讨电视胸腔镜(VATS)解剖性肺段切除术与肺叶切除术治疗Ia 期非小细胞肺癌(NSCLC)患者的手术情况及对患者肺功能的影响。方法:选取我院手术治疗的Ⅰa期NSCLC患者,收集时间2014年1月至2016年12月,根据术式不同分为两组,均采用VATS手术治疗,A组(54例)患者采用解剖性肺段切除术、B组(60例)采用肺叶切除术治疗,对比两组患者的手术效果及术后肺功能变化。结果:A组患者的手术时间、清扫淋巴结数目与B组比较差异无统计学意义(P>0.05);A组患者的手术出血量、术后胸腔引流量、术后拔管时间、术后住院时间均显著的低于B组患者(P<0.05);术前,A组和B组患者的FEV1%、FVC%、MVV%测定值差异无统计学意义(P>0.05),术后3个月复查,A组患者的FEV1%、FVC%、MVV%测定值均显著高于B组患者(P<0.05);手术后,A组患者的并发症发生率(7.41%)低于B组患者(13.33%),但是差异无统计学意义(P>0.05)。结论:VATS解剖性肺段切除术治疗Ⅰa期NSCLC患者具有手术创伤小、术后恢复快、对患者肺功能影响更小的优势。 相似文献
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目的研究单孔胸腔镜肺段切除术在Ⅰa期非小细胞肺癌患者治疗中的应用效果。方法采用回顾性分析方法,研究对象为2017年1月至2020年1月阜阳市第五人民医院收治的70例Ⅰa期非小细胞肺癌患者,根据不同手术方式分为对照组与研究组,各35例。对照组选用单孔胸腔镜肺叶切除术治疗,研究组选用单孔胸腔镜肺段切除术治疗。比较2组手术指标(淋巴清扫数量、术中出血量、手术时长)、术后指标(分钟通气量、住院时长、疼痛程度、引流量、胸管留置时间)与术前、术后6个月肺功能指标[用力肺活量(FVC)、第1秒用力呼气量(FEV1)]水平变化及并发症(心律失常、肺漏气、切口感染、肺部感染)发生率。结果研究组淋巴清扫数量、术中出血量、手术时长、分钟通气量、住院时长、疼痛程度、引流量、胸管留置时间,术后6个月FVC、FEV1及并发症发生率依次为(10.41±1.82)枚、(190.34±50.12)mL、(138.17±30.78)min、(6.21±0.23)L、(6.05±0.68)d、(3.19±0.56)分、(141.09±42.34)mL、(3.98±1.25)d、(79.84±3.28)%、(83.76±4.11)%、8.57%,对照组依次为(10.45±1.88)枚、(306.63±61.48)mL、(117.96±28.58)min、(5.12±0.20)L、(8.41±0.98)d、(3.24±0.58)分、(141.29±42.55)mL、(4.05±1.28)d、(76.32±3.01)%、(76.03±3.62)%、14.29%。研究组较对照组术后FVC、FEVl更高,术中出血量更少,手术时间更长,住院时间更短,分钟通气量更多,差异有统计学意义(P<0.05);2组淋巴清扫数量、疼痛评分、引流量、胸管置留时间及并发症发生率比较,差异无统计学意义(P>0.05)。结论胸腔镜肺段切除术相较于胸腔镜肺叶切除术对患者肺功能产生的影响较小,住院时间更短,术中出血量更少,肺通气量更高。 相似文献
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Alex J. Lancaster Victor R. Carlson Christopher E. Pelt Lucas A. Anderson Christopher L. Peters Jeremy M. Gililland 《The Journal of arthroplasty》2021,36(6):2178-2183
BackgroundTwo-stage revision remains the standard of care for prosthetic joint infection after total hip arthroplasty. However, there are substantial complications associated with articulating antibiotic hip spacers. Handmade and molded spacers have been shown to have higher rates of spacer fracture than antibiotic-coated prostheses (ACPs). The aim of this study is to review outcomes with an implant that is often categorized as an ACP spacer, the Zimmer-Biomet StageOne Select Femoral Spacer (ZBSO).MethodsA retrospective review was performed of 63 patients who underwent placement of a ZBSO. Patients were compared based on whether or not an extended trochanteric osteotomy (ETO) was performed using Fisher’s exact and t-tests.ResultsFive patients were excluded due to lack of follow-up or death shortly after stage 1 surgery, leaving 58 patients. Spacer fracture was noted in 5 of 58 patients (8.6%). Sixteen patients underwent ETO and 25.0% suffered a spacer fracture compared to 2.3% without ETO (odds ratio 13.7, P = .0248). There was no association between patient demographics or ETO length and spacer fracture. Two patients had periprosthetic fractures (3.4%) and 4 had dislocations (6.9%). Forty-nine patients (84.4%) went on to second-stage revision; of those 26.5% failed to clear the infection and required an average of 2.2 additional surgeries.ConclusionThe ZBSO spacer has overall complication rates similar to previously reported spacer series. Although the ZBSO looks like an ACP spacer, in the setting of ETO, it behaves like a molded or handmade spacer with a high rate of spacer fracture (25%) due to the small diameter of the core. This implant should be used with caution in combination with an ETO. 相似文献
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《Paediatrics & Child Health》2022,32(5):171-177
Neuroblastoma is one of the commonest childhood cancers and typically affects very young children. It is characterized by a very broad spectrum of clinical presentation and outcome, driven by the biology of the tumour. This ranges from ‘low risk’ tumours, most commonly found in infants, which may spontaneously regress and have an excellent prognosis with minimal or no treatment, to ‘high risk’ disease, which carries a poor prognosis despite intensive multi-modal treatment. Although particular presentations may be associated with favourable or unfavourable outcome, the clinical features may mask the underlying biology of the tumour and a full assessment of the clinical and biological features is required to determine appropriate treatment. The International Neuroblastoma Risk Group classification, based on the age of the patient and the stage, grade and genetics of the tumour, is used to stratify treatment according to risk factors. This review provides an overview of current neuroblastoma management, focusing on how classification is applied in practice, and how this is used to determine individual patient treatment. The challenges that remain in treating patients with high-risk disease are discussed. 相似文献
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目的 应用多层螺旋CT(MSCT)对健康人左肺上叶肺静脉解剖及引流模式分型,为解剖性肺段切除术提供帮助。 方法 收集200例肺无异常胸部CT影像资料,通过容积重建(volume reconstruction,VR)获得静脉解剖及引流模式图,统计各静脉分型出现率;重建5 mm轴位最大密度投影(maximum density projection,MIP)图,辨识对应各分型。 结果 左肺上叶静脉根据共干情况不同可分为:V1+2型,V2+3型,及V1+2a V2+3bc型,其出现率分别为69%(138/200)、17.5%(35/200)、13.5%(27/200)。其特点为:V1+2为V1与V2共干,其各自发出属支相互无联系;V2+3型中V2与V3共干,V1与V2+3分别汇入左上肺静脉干;V1+2a V2+3bc型,此型主要是V2变异较大。左肺上叶舌段静脉V4、V5共干时,其属支各自无联系,V4存在与V3b共干的情况,并各自具有不同的引流特点。 结论 左肺上叶因舌段的存在,其静脉分型更为复杂,MSCT所得静脉解剖及引流模式图结合5 mm轴位MIP图可清楚显示肺静脉解剖分型,作为其解剖识别常规手段。 相似文献
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Takashi Zaitsu Mari Ohnuki Yuichi Ando Yoko Kawaguchi 《International dental journal》2022,72(1):100-105
ObjectivesAlthough extensive national oral health data on dental caries and periodontal diseases in Japan are available, few studies have assessed the occlusal status of the Japanese population, and none are based on national survey data. The presence and prosthodontic conditions of the molar region are important for masticatory function, and the functional tooth unit (FTU) approach can be used to evaluate the occlusal status. Thus, using the national oral health survey data, this study investigated the occlusal status of the Japanese population using FTU.MethodsOverall, 3,605 adults (aged ≥20 years) who participated in the 2011 Japanese national oral health survey were included. FTUs were used as indices for evaluating the occlusal status. FTUs were calculated according to sex, age group, and the number of teeth present, and their associations were further analysed.ResultsThe number of teeth present, posterior teeth, and FTUs decreased with age in both men and women. In the age group of those ≥60 years, all only natural teeth-FTU (n-FTU) and natural teeth and artificial teeth from fixed prostheses or implant-supported FTU (nif-FTU) scores were <8. The total-FTU scores of all age groups, except the 60-69 and 70-79 years age groups, were >10.ConclusionThis is the first study to use FTUs and national oral health survey data to investigate the occlusal status in the Japanese population. People aged ≥60 years who have low n-FTU or natural teeth and artificial teeth from fixed prostheses or implant-supported FTU scores or those aged 60-70 years who have the lowest total-FTU scores require careful evaluation of masticatory performance. 相似文献
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