Fibrolipoma of the Perineum: A Case Report

Fibrolipoma is a low-frequency type of lipoma. Idiopathic, benign, and relatively slow-growing tumors, lipoma arise from exclusively mature adipocytes. Fibrolipoma are characterized by adipocytes mixed with abundant fibrous bands. Large, pendulous fibrolipomata are even more unusual. This article describes the etiology, incidence, clinical presentation, and management of a pendulous fibrolipoma in an adult transgender male. The lesion had the appearance of a scrotal sac. Surgical ablation was performed with pathologic examination. Pathology findings are presented, along with discussion of the role of the advanced practice clinician in diagnosis and management.     

There is fat in this sclerosis: A case report of sclerotic lipoma and review of the literature

Sclerotic lipomas, a lipoma variant, are benign subcutaneous tumors, so-named because of their resemblance to sclerotic fibromas. Previous literature has suggested that these tumors may show a predilection for middle-aged adult males. We report an unusual case of a sclerotic lipoma diagnosed on the scalp of a 66-year-old female. The patient presented to the outpatient clinic with a 3- to 4-year history of an enlarging and irritated 2.6-cm nodule on the anterior crown of the scalp, clinically thought to be a pilar cyst. Histopathological examination from the excisional specimen revealed a well-circumscribed dermal to subcutaneous tumor with ample sclerotic collagen bundles, an increased number of CD34 positive spindled cells, and prominent S-100 positive mature adipocytes comprising greater than 50% of the tumor. We present this case given its atypical clinical and histopathological presentation, review the literature of sclerotic lipomas, and discuss the differential diagnosis to raise awareness of this rare entity.     

Multiple cardiac lipomas and pericardial lipomatosis: Multidedector-row computer tomography findings

Being rare tumors of the heart, cardiac lipomas are usually discovered incidentally during non-cardiac-related examinations of the chest. Although they are reported to be typically solitary, multiplicity has been described in tuberosclerosis patients. Here we reported the multidedector-row computer tomography (MDCT) findings of a nontuberosclerosis case with multiple cardiac lipomas along with pericardial lipomatosis, who presented with symptoms of left heart failure after a histerectomy surgery but otherwise healthy before that operation.     

Balloon-assisted endoscopic submucosal dissection for treating small intestinal lipomas: Report of two cases

BACKGROUNDMost small intestinal lipomas are treated surgically, and some require repeated surgeries for multiple lipomas. However, application of endoscopic submucosal dissection (ESD) technology in the deep small intestine is rarely reported owing to the special anatomical structure of the small intestine, medical equipment limitations, and the lack of relevant experience among endoscopists.CASE SUMMARYTwo patients with small intestinal lipomas treated at the Air Force Medical Center from November 2015 to September 2019 were selected to undergo balloon-assisted ESD to treat the lipomas and explore the technical feasibility and safety of ESD for treating small intestinal lipomas. The two patients successfully underwent balloon-assisted ESD to treat four small intestinal lipomas, with a complete resection rate of 100% (4/4), without intraoperative or postoperative bleeding, perforation, or other complications. After 3-6 mo of postoperative follow-up, the clinical symptoms caused by the lipomas were significantly relieved or disappeared after treatment.CONCLUSIONBalloon-assisted ESD is a safe and reliable new method for treating deep intestinal lipomas and shows good clinical feasibility.