全文获取类型
收费全文 | 1034篇 |
免费 | 46篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 109篇 |
妇产科学 | 42篇 |
基础医学 | 150篇 |
口腔科学 | 19篇 |
临床医学 | 49篇 |
内科学 | 163篇 |
皮肤病学 | 29篇 |
神经病学 | 74篇 |
特种医学 | 34篇 |
外科学 | 164篇 |
综合类 | 29篇 |
预防医学 | 23篇 |
眼科学 | 43篇 |
药学 | 75篇 |
中国医学 | 2篇 |
肿瘤学 | 64篇 |
出版年
2023年 | 6篇 |
2021年 | 29篇 |
2020年 | 12篇 |
2019年 | 15篇 |
2018年 | 46篇 |
2017年 | 21篇 |
2016年 | 21篇 |
2015年 | 41篇 |
2014年 | 31篇 |
2013年 | 37篇 |
2012年 | 69篇 |
2011年 | 65篇 |
2010年 | 43篇 |
2009年 | 30篇 |
2008年 | 56篇 |
2007年 | 51篇 |
2006年 | 49篇 |
2005年 | 48篇 |
2004年 | 49篇 |
2003年 | 37篇 |
2002年 | 29篇 |
2001年 | 19篇 |
2000年 | 40篇 |
1999年 | 29篇 |
1998年 | 8篇 |
1997年 | 7篇 |
1996年 | 5篇 |
1994年 | 8篇 |
1993年 | 6篇 |
1992年 | 12篇 |
1991年 | 11篇 |
1990年 | 8篇 |
1989年 | 6篇 |
1988年 | 8篇 |
1987年 | 14篇 |
1986年 | 13篇 |
1985年 | 16篇 |
1984年 | 10篇 |
1983年 | 7篇 |
1982年 | 4篇 |
1980年 | 3篇 |
1979年 | 9篇 |
1977年 | 3篇 |
1976年 | 5篇 |
1975年 | 4篇 |
1974年 | 8篇 |
1973年 | 4篇 |
1971年 | 7篇 |
1968年 | 4篇 |
1963年 | 3篇 |
排序方式: 共有1081条查询结果,搜索用时 15 毫秒
1.
2.
Purpose: To compare treatment outcome of screw proximal femoral nail (PFN) system with that of a
helical PFN.
Methods: The study included 77 patients with closed unstable intertrochanteric fracture classified as AO 31A2 & 31A3, between June 2008 to August 2011. Inclusion criteria were: all mature skeletons above 50 years of age; closed unstable trochanteric fracture classified as AO 31A2 & A3. Exclusion criteria were: immature skeleton, pathological fracture of any cause other than osteoporosis, inability to walk independently prior to injury. Patients were randomized to 2 treatment groups based on admission sequence. Forty patients were treated with screw PFN and thirty seven were treated with helical PFN.
Results: Both groups were similar in respect of time of surgery, blood loss and functional assessment and duration of hospitalization. In screw PFN group 2 patients had superficial wound infection, 1 patient had persistent hip pain and 1 patient had shortening >1 cm but <2 cm, while in helical PFN group 1 patient had superficial wound infection.
Conclusion: Both screw and helical PFN are very effective implants in osteoporotic and unstable
trochanteric fractures even in Indian patients where the bones are narrow and neck diameter is small. It is an implant of choice for osteoporotic and unstable trochanteric fractures. 相似文献
3.
4.
Jack E. Steiner Garrett N. McCoy Christopher P. Hess William B. Dobyns Denise W. Metry Beth A. Drolet Mohit Maheshwari Dawn H. Siegel 《American journal of medical genetics. Part A》2018,176(1):48-55
PHACE syndrome is the association of segmental facial hemangiomas with congenital arterial, brain, cardiac, and ocular anomalies. Structural brain malformations affect 41–52% of PHACE patients and can be associated with focal neurologic deficits, developmental delays, and/or intellectual disability. To better characterize the spectrum of structural brain and other intracranial anomalies in PHACE syndrome, MRI scans of the head/neck were retrospectively reviewed in 55 patients from the PHACE Syndrome International Clinical Registry and Genetic Repository. All registry patients with a diagnosis of definite PHACE syndrome who had MRI scans of satisfactory quality were included. Of 55 patients, 34 (62%) demonstrated ≥1 non‐vascular intracranial anomaly; structural brain malformations were present in 19 (35%). There was no difference in the prevalence of brain anomalies between genders. Brain anomalies were more likely in patients with S1 and/or S2 distribution of facial hemangioma. The most common structural brain defects were cerebellar hypoplasia (25%) and fourth ventricle abnormalities (13%). Dandy–Walker complex and malformations of cortical development were present in 9% and 7%, respectively. Extra‐axial findings such as pituitary anomalies (18%) and intracranial hemangiomas (18%) were also observed. Six patients (11%) had anomalies of the globes or optic nerve/chiasm detectable on MRI. Brain malformations comprise a diverse group of structural developmental anomalies that are common in patients with PHACE syndrome. Along with brain malformations, numerous abnormalities of the pituitary, meninges, and globes were observed, highlighting the need for careful radiologic assessment of these structures in the neuroimaging workup for PHACE syndrome. 相似文献
5.
Irappa Madabhavi Apurva Patel Asha Anand Pritam Kataria Nagaveni Kadakol Malay Sarkar 《Journal of the Association for Vascular Access》2018,23(1):23-29
Background
Effective and reliable venous access is among the cornerstones of modern medical therapy in oncology.Materials and Methods
This was a prospective observational study of collected data of patients with a diagnosis of any cancer, at a tertiary care oncology hospital in Ahmadabad, Gujarat, India, during a 2-year period.Results
A Hickman catheter was inserted in 200 patients and most commonly used in solid malignancies (n?=?103; 51.5%), followed by hematologic conditions (n?=?93; 48.5%). Among solid malignancies, hepatoblastoma (n?=?21; 10.5%) was the most common indication, whereas in hematologic malignancies acute lymphoblastic leukemia was the most common indication (n?=?56; 28%) for Hickman catheter insertion. Hickman catheters were inserted most commonly in the right side (n?=?170; 85%) of the venous system. The various complications in the Hickman study group in descending order were 28 patients (14%) developed arrhythmias, 15 patients (7.5%) developed infection, 12 patients (6%) developed bleeding, 8 patients (4%) developed pneumothorax, 7 patients (3.5%) developed catheter blockage, and 6 patients (3%) required premature catheter removal. The median time of Hickman catheter in situ was 207 days.Conclusions
The most disturbing aspect of treatment of patients with cancer is multiple painful venipunctures made for administration of cytotoxic agents, antibiotics, blood products, and nutritional supplements. The focus of this prospective observational research was to study the various indications for Hickman catheter in different solid and hematologic malignancies as well as the various complications and outcomes in pediatric and adult cancer patients. 相似文献6.
Kimona Issa Qais Naziri Aditya V. Maheshwari Vijay J. Rasquinha Ronald E. Delanois Michael A. Mont 《The Journal of arthroplasty》2013
The purpose of this study was to compare the outcomes of cementless primary total hip arthroplasty (THA) in sickle cell patients compared to the remaining cohort of osteonecrosis patients who did not have this disease. Thirty-two sickle cell patients (42 hips) who had a mean age of 37 years and mean follow-up of 7.5 years (range, 5–11 years) were compared to 87 non-sickle cell osteonecrosis patients (102 hips) who had mean age of 43 years and mean follow-up of 7 years (range, 3–10.5 years). Outcomes evaluated included implant survivorship, Harris hip scores, complication rates, radiographic outcomes, and Short Form-(SF-36) health questionnaire. There were no significant differences in aseptic implant survivorship (95 vs. 97%), Harris hip scores (87 vs. 88 points), SF-36 score, or radiographic findings between the two patient cohorts. In light of these findings, we believe that the outcomes of THA improved in sickle cell patients with optimized medical management and the use of cementless prosthetic devices. 相似文献
7.
The causes for internal hernias can be broadly classified as congenital or acquired, the latter being caused by post surgical
or traumatic defects. An internal hernia following nephrectomy is a relatively rare occurrence. A nephrectomy via the transperitoneal
approach has complications which are common to any abdominal surgery, as well as some which are specific to it. However, an
internal hernia through the descending mesocolon is rare, and, to the best of our knowledge, very few cases have been reported
in the literature. We report a case of internal hernia through the descending mesocolon following left radical nephrectomy,
review the available literature on this observation and discuss its pathogenesis and prevention. 相似文献
8.
Atul Maheshwari Michael Fischer Pierluigi Gambetti Alicia Parker Aarthi Ram Claudio Soto Luis Concha-Marambio Yvonne Cohen Ermias D. Belay Ryan A. Maddox Simon Mead Clay Goodman Joseph S. Kass Lawrence B. Schonberger Haitham M. Hussein 《Emerging infectious diseases》2015,21(5):750-759
Variant Creutzfeldt-Jakob disease (vCJD) is a rare, fatal prion disease resulting from transmission to humans of the infectious agent of bovine spongiform encephalopathy. We describe the clinical presentation of a recent case of vCJD in the United States and provide an update on diagnostic testing. The location of this patient’s exposure is less clear than those in the 3 previously reported US cases, but strong evidence indicates that exposure to contaminated beef occurred outside the United States more than a decade before illness onset. This case exemplifies the persistent risk for vCJD acquired in unsuspected geographic locations and highlights the need for continued global surveillance and awareness to prevent further dissemination of vCJD. 相似文献
9.
Shailesh Anand Sable Sharad Maheshwari Swapnil Sharma Kapildev Yadav Ashutosh Chauhan Sorabh Kapoor Vibha Varma Vinay Kumaran 《Indian journal of gastroenterology》2018,37(2):133-140
Background/Aim
Right lobe living donor (2/3rd partial hepatectomy) model is the best way to accurately study liver regeneration process in human beings. We aimed to study the kinetics of liver regeneration after 2/3rd partial hepatectomy in donors.Methods
Retrospective analysis of prospectively maintained volumetric recovery data in donors was performed in 23 donors, who underwent 29 contrast-enhanced computed tomography within 3 months for various clinical indications.Results
The absolute volumetric growth percentages were as follows: 37.60?±?21.74 at 1st week, 92?±?53.27 at 2nd week, 115.55?±?59.65 at 4th week, and 110.79?±?64.47 at 3 months. On sub-group analysis of our cohort, we found that 4.3%, 17%, 30.4%, and 39% donors attended ≥?90% volumetric recovery at 1st, 2nd, 4th week, and 3 months, respectively. One patient at 4th week revealed 128% volumetric recovery. There was one more patient who exceeded original total liver volumes (TLV) (111% of TLV) at 2.5 months. The serum bilirubin and INR values peaked at postoperative day (POD) 3rd and then started showing a downward trend from POD 5th onwards.Conclusion
Our study is the first to document complete volumetric recovery in donors as early as 3 weeks. Two of the donors overshot their original TLV during the early regenerative phase.10.