全文获取类型
收费全文 | 3077篇 |
免费 | 147篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 50篇 |
儿科学 | 148篇 |
妇产科学 | 41篇 |
基础医学 | 441篇 |
口腔科学 | 45篇 |
临床医学 | 224篇 |
内科学 | 740篇 |
皮肤病学 | 90篇 |
神经病学 | 203篇 |
特种医学 | 62篇 |
外科学 | 469篇 |
综合类 | 105篇 |
预防医学 | 150篇 |
眼科学 | 85篇 |
药学 | 175篇 |
中国医学 | 7篇 |
肿瘤学 | 197篇 |
出版年
2023年 | 34篇 |
2022年 | 32篇 |
2021年 | 106篇 |
2020年 | 67篇 |
2019年 | 76篇 |
2018年 | 93篇 |
2017年 | 73篇 |
2016年 | 106篇 |
2015年 | 108篇 |
2014年 | 132篇 |
2013年 | 142篇 |
2012年 | 227篇 |
2011年 | 203篇 |
2010年 | 119篇 |
2009年 | 107篇 |
2008年 | 170篇 |
2007年 | 167篇 |
2006年 | 147篇 |
2005年 | 159篇 |
2004年 | 162篇 |
2003年 | 160篇 |
2002年 | 117篇 |
2001年 | 68篇 |
2000年 | 55篇 |
1999年 | 52篇 |
1998年 | 28篇 |
1997年 | 19篇 |
1996年 | 14篇 |
1995年 | 20篇 |
1993年 | 8篇 |
1992年 | 16篇 |
1991年 | 27篇 |
1990年 | 22篇 |
1989年 | 18篇 |
1988年 | 10篇 |
1987年 | 18篇 |
1986年 | 16篇 |
1985年 | 17篇 |
1984年 | 12篇 |
1982年 | 8篇 |
1981年 | 5篇 |
1980年 | 6篇 |
1979年 | 12篇 |
1978年 | 5篇 |
1977年 | 5篇 |
1976年 | 6篇 |
1974年 | 6篇 |
1971年 | 5篇 |
1970年 | 7篇 |
1945年 | 5篇 |
排序方式: 共有3232条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
7.
8.
Stefan S du Plessis Ashok Agarwal Gayatri Mohanty Michelle van der Linde 《Asian journal of andrology》2015,17(2):230-235
Spermatozoa are highly specialized cells. Adenosine triphosphate (ATP), which provides the energy for supporting the key functions of the spermatozoa, is formed by 2 metabolic pathways, namely glycolysis and oxidative phosphorylation (OXPHOS). It is produced in the mitochondria through OXPHOS as well as in the head and principal piece of the flagellum through glycolysis. However, there is a great discrepancy as to which method of ATP production is primarily utilized by the spermatozoa for successful fertilization. Mitochondrial respiration is considered to be a more efficient metabolic process for ATP synthesis in comparison to glycolysis. However, studies have shown that the diffusion potential of ATP from the mitochondria to the distal end of the flagellum is not sufficient to support sperm motility, suggesting that glycolysis in the tail region is the preferred pathway for energy production. It is suggested by many investigators that although glycolysis forms the major source of ATP along the flagellum, energy required for sperm motility is mainly produced during mitochondrial respiration. Nevertheless, some studies have shown that when glycolysis is inhibited, proper functioning and motility of spermatozoa remains intact although it is unclear whether such motility can be sustained for prolonged periods of time, or is sufficiently vigorous to achieve optimal fertilization. The purpose of this article is to provide an overview of mammalian sperm energy metabolism and identify the preferred metabolic pathway for ATP generation which forms the basis of energy production in human spermatozoa during fertilization. 相似文献
9.
Ranjan Gupta Amiya Kumar Nath Murugavel Subbian Debdatta Basu Abdoul Hamide Mariette D'Souza 《Indian journal of dermatology》2016,61(2):203-205
Plasma cell leukemia (PCL) is a rare lymphoproliferative disorder characterized by a malignant proliferation of plasma cells (PC) in blood and marrow. Cutaneous involvement is very rare in PCL. We present the case of a 45-year-old lady who presented with multiple hemorrhagic nodules and plaques in the skin. Her total leucocyte count was 2,00,200/cmm with 85% abnormal plasmacytoid cells in peripheral smear. Biopsy of the skin lesions revealed diffuse infiltration by plasma cells with ‘choked’ blood vessels. A diagnosis of plasma cell leukemia with cutaneous involvement was made. On the second day of admission, the patient expired probably because of intracranial bleed due to thrombocytopenia. Post-mortem bone marrow and liver biopsy also showed diffuse infiltration by plasma cells. Monoclonality of the cells was proven by demonstrating the production of only kappa light chains. 相似文献
10.