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ObjectiveThis scoping review explores the potential for virtual environments (VE) to evaluate emotional outcomes in clinical communication research. Authors representing multiple disciplines use review results to propose potential research opportunities and considerations.MethodsWe utilized a structured framework for scoping reviews. We searched four literature databases for relevant articles. We applied multidisciplinary perspectives to synthesize relevant potential opportunities for emotion-focused communications research using VE.ResultsTwenty-one articles met inclusion criteria. They applied different methodological approaches, including a range of VE technologies and diverse emotional outcome measures, such as psychophysiological arousal, emotional valence, or empathy. Major research topics included use of virtual reality to provoke and measure emotional responses, train clinicians in communication skills, and increase clinician empathy.ConclusionResearchers may leverage VE technologies to ethically and systematically examine how characteristics of clinical interactions, environments, and communication impact emotional reactions and responses among patients and clinicians. Variability exists in how VE technologies are employed and reported in published literature, and this may limit the internal and external validity of the research. However, virtual reality can provide a low-cost, low-risk, experimentally controlled, and ecologically valid approach for studying clinician-patient communication.Practice implicationsFuture research should leverage psychophysiological measures to further examine emotional responses during clinical communication scenarios and clearly report virtual environment characteristics to support evaluation of study conclusions, study replicability, and meta-analyses.  相似文献   
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This study used event‐related potentials to examine interactions between mood, sentence context, and semantic memory structure in schizophrenia. Seventeen male chronic schizophrenia and 15 healthy control subjects read sentence pairs after positive, negative, or neutral mood induction. Sentences ended with expected words (EW), within‐category violations (WCV), or between‐category violations (BCV). Across all moods, patients showed sensitivity to context indexed by reduced N400 to EW relative to both WCV and BCV. However, they did not show sensitivity to the semantic memory structure. N400 abnormalities were particularly enhanced under a negative mood in schizophrenia. These findings suggest abnormal interactions between mood, context processing, and connections within semantic memory in schizophrenia, and a specific role of negative mood in modulating semantic processes in this disease.  相似文献   
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ObjectiveTo develop an item response theory (IRT)-calibrated spinal cord injury (SCI)-specific Positive Affect and Well-being (PAWB) item bank with flexible options for administration.DesignQualitative feedback from patient and provider focus groups was used to expand on the Neurological Disorders and Quality of Life (Neuro-QOL) positive affect & well-being item bank for use in SCI. New items were created and revised based on expert review and patient feedback and were then field tested. Analyses included confirmatory factor analysis, graded response IRT modeling and evaluation of differential item functioning (DIF).SettingWe tested a 32-item pool at several rehabilitation centers across the United States, including the University of Michigan, Kessler Foundation, Rehabilitation Institute of Chicago, the University of Washington, Craig Hospital and the James J. Peters/Bronx Department of Veterans Affairs hospital.ParticipantsA total of 717 individuals with SCI answered the PAWB questions.ResultsA unidimensional model was observed (Confirmatory Fit Index = 0.947; Root Mean Square Error of Approximation = 0.094) and measurement precision was good (reliability in theta of –2.9 to 1.2 is roughly equivalent to classical reliability of 0.95 or above). Twelve items were flagged for DIF, however, after examination of effect sizes, the DIF was determined to be negligible and would have little practical impact on score estimates. The final calibrated item bank resulted in 28 retained itemsConclusionsThis study indicates that the Spinal Cord Injury – Quality of Life PAWB bank represents a psychometrically robust measurement tool. Short form items are also suggested and a computer adaptive test is available.  相似文献   
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Previous research indicates that the reward positivity (RewP), an electrophysiological correlate of sensitivity and biases towards rewarding stimuli, is modulated by affective and motivational variables. Studies have provided evidence that states and traits associated with negative affect and reduced approach motivation are correlated with smaller RewP amplitudes. However, the possible confound of affective valence and motivational direction was not addressed in these studies. In the present study, we examined if anger, an emotion associated with negative affect and increased approach motivation, would affect RewP amplitude. We also investigated if RewP amplitude was related to the motivational properties of reward stimuli. One hundred male participants completed two emotion inductions intended to elicit feelings of either neutrality or anger. Each was followed by a simple gambling task, in which correct choices were followed by images of women in lingerie or swimwear. Although the RewP was elicited following each induction, there was no difference in amplitude between the neutral and anger induction. However, RewP amplitude was positively correlated with how much participants liked the reward stimuli, and this correlation was statistically larger following the anger induction. These results support a motivational interpretation for the differences in RewP amplitude reported in previous studies, suggesting that motivational direction and intensity, rather than affective valence, underlie differences in RewP amplitude. Moreover, the RewP appears to be affected by interactions between motivational state and the motivational value of reward stimuli.  相似文献   
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《Brain stimulation》2022,15(3):615-623
BackgroundStimulation of the ventromedial hypothalamic region in animals has been reported to cause attack behavior labeled as sham-rage without offering information about the internal affective state of the animal being stimulated.ObjectiveTo examine the causal effect of electrical stimulation near the ventromedial region of the human hypothalamus on the human subjective experience and map the electrophysiological connectivity of the hypothalamus with other brain regions.MethodsWe examined a patient (Subject S20_150) with intracranial electrodes implanted across 170 brain regions, including the hypothalamus. We combined direct electrical stimulation with tractography, cortico-cortical evoked potentials (CCEP), and functional connectivity using resting state intracranial electroencephalography (EEG).ResultsRecordings in the hypothalamus did not reveal any epileptic abnormalities. Electrical stimulations near the ventromedial hypothalamus induced profound shame, sadness, and fear but not rage or anger. When repeated single-pulse stimulations were delivered to the hypothalamus, significant responses were evoked in the amygdala, hippocampus, ventromedial-prefrontal and orbitofrontal cortices, anterior cingulate, as well as ventral-anterior and dorsal-posterior insula. The time to first peak of these evoked responses varied and earliest propagations correlated best with the measures of resting-state EEG connectivity and structural connectivity.ConclusionThis patient's case offers details about the affective state induced by the stimulation of the human hypothalamus and provides causal evidence relevant to current theories of emotion. The complexity of affective state induced by the stimulation of the hypothalamus and the profile of hypothalamic electrophysiological connectivity suggest that the hypothalamus and its connected structures ought to be seen as causally important for human affective experience.  相似文献   
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ObjectiveTo determine associations between patient affect and physician liking of the patient, and their associations with physician behavior and patient-reported outcomes.MethodsStructural equation modeling based on coding of 497 videotaped hospital encounters, with questionnaires assessing pre-visit patient affect, post-visit patient affect and encounter evaluations, and physician liking of the patient, involving 71 physicians.ResultsIn first visits, patient reported outcomes were strongly correlated with physician behavior and less so with physician liking, while in later visits, patient reported outcomes were directly related to physician liking and not mediated by physician behavior. Physician liking predicted physician behavior, more for female physicians in first visits. Patient negative affect before the visit was negatively associated with male physicians’ liking. When acquainted, both patient positive and negative affect were associated with physician liking.ConclusionPhysician liking of the patient plays a dynamic role in a consultation, is influenced by patient pre-encounter affect, and influences physician behavior. The dynamics are different in first and later visits, and influenced by physician gender.Practice implicationsPhysicians should be aware how patient affect influences their behavior, and administrators should take any prior relationship between patient and physician into account when evaluating patient reported outcomes.  相似文献   
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This article focuses on Lars von Trier's 2011 film, Melancholia, described as ‘a beautiful film about the end of the world’ and interlocking personal and global tragedy. Drawing directly on her personal emotional response to the film, and referring to her profound incapacity to talk about it for many years after an initial encounter with it, the author turns to a range of object relations psychoanalytic thinkers to consider what such experience has to say about lived emotional relationships to cinema, and its role in shaping and articulating psychological, and affective states. The article touches on debates about the cinematic gaze, and the role of film as a psychological object, and considers whether film might be seen as offering a form of therapeutic encounter for viewers.  相似文献   
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目的探讨MRI和CT影像分度在新生儿HIE脑损伤程度评估中的应用价值。方法统计分析江苏省徐州市儿童医院放射科2013年6月至2014年6月收治的100例HIE患儿的临床资料。结果 100例HIE患儿的影像检查结果中,CT的检出率和假阴性率分别为91.4%和8.6%,MRI的检出率为100%。临床分度和CT新法分度、MRI分度之间显著相关(列联系数=0.731和0.723,P0.05)。结论 MRI和CT影像分度在新生儿HIE脑损伤程度评估能够作为重要的诊断参考指证。MRI比CT具有较高的异常检出率,能够更早将基底核损伤检测出来,而CT更能将蛛网膜下腔出血寻找出来,均具有较高的应用价值。  相似文献   
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